Results 151 to 160 of about 59,469 (309)

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

open access: yesPhotochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal   +3 more
wiley   +1 more source

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye   +5 more
wiley   +1 more source

Does Micronucleus Score Significantly Correlate with Dysplasia in Cervical Pap Smears?

open access: diamond, 2020
Debarshi Saha   +5 more
openalex   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza   +4 more
wiley   +1 more source

Morphology, Ontogenesis, and Multi‐Gene Phylogeny of the Type Species Cyrtohymena muscorum (Kahl, 1932) Foissner, 1989 (Alveolata, Ciliophora, Hypotricha)

open access: yesZoologica Scripta, EarlyView.
ABSTRACT Members of the oxytrichid genus Cyrtohymena are characterised by a distinctive undulating membranes type, known as the Cyrtohymena pattern, featuring a strongly curved stichodyad paroral that forms a semicircle distally. Although the type species, Cyrtohymena muscorum, has been redescribed morphologically, its ontogenesis remains poorly ...
Atef Omar, Jae‐Ho Jung
wiley   +1 more source

Sewage sludge does not induce genotoxicity and carcinogenesis

open access: yesGenetics and Molecular Biology, 2012
Through a series of experiments, the genotoxic/mutagenic and carcinogenic potential of sewage sludge was assessed. Male Wistar rats were randomly assigned to four groups: Group 1 - negative control; Group 2 - liver carcinogenesis initiated by ...
Paula Regina Pereira Silva   +3 more
doaj  

Application of cell sorting for enhancing the performance of the cytokinesis-block micronucleus assay [PDF]

open access: gold, 2016
Ayumi Nakamura   +4 more
openalex   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

open access: yesExperimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

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