Results 41 to 50 of about 59,469 (309)

Association between human papillomavirus (HPV) DNA and micronuclei in normal cervical cytology [PDF]

Genetics and Molecular Biology, 2014
The aim of the present study was to investigate the association between HPV-DNA and micronucleus (MN) frequency in women with normal cervical cytology. A total of 158 normal cervical smears were analyzed cytologically.
Ana Paula Rebelo Cassel, Regina Bones Barcellos, Cláudia Maria Dornelles da Silva, Sabrina Esteves de Matos Almeida, Maria Lucia Rosa Rossetti   +4 more
doaj   +1 more source

Low doses of ochratoxin A induce micronucleus formation and delay DNA repair in human lymphocytes [PDF]

, 2014
The contamination of food commodities by fungal toxins has attracted great interest because many of these mycotoxins are responsible for different diseases, including cancer and other chronic illnesses. Ochratoxin A (OTA) is a mycotoxin naturally present
Barrón-Vivanco, Briscia S., Benitez-Trinidad, alma B., González Arias, Cyndia A., Marín Sillué, Sònia, Medina-Díaz, Irma M., Ramos Girona, Antonio J., Robledo-Marenco, Lourdes, Rojas-García, A. E., Sanchís Almenar, Vicente, Sordo, Montserrat   +9 more
core   +2 more sources

Suitability of a Cellulose-Based Nanomaterial for the Remediation of Heavy Metal Contaminated Freshwaters: A Case-Study Showing the Recovery of Cadmium Induced DNA Integrity Loss, Cell Proliferation Increase, Nuclear Morphology and Chromosomal Alterations on Dreissena polymorpha

Nanomaterials, 2020
The contamination of freshwaters by heavy metals represents a great problem, posing a threat for human and environmental health. Cadmium is classified as carcinogen to humans and its mechanism of carcinogenicity includes genotoxic events. In this study a
Patrizia Guidi, Margherita Bernardeschi, Mara Palumbo, Massimo Genovese, Vittoria Scarcelli, Andrea Fiorati, Laura Riva, Carlo Punta, Ilaria Corsi, Giada Frenzilli   +9 more
doaj   +1 more source

Genetic determinants of micronucleus formation in vivo

Nature
Genomic instability arising from defective responses to DNA damage1 or mitotic chromosomal imbalances2 can lead to the sequestration of DNA in aberrant extranuclear structures called micronuclei (MN).
D. J. Adams, B. Barlas, R. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. Speak, N. Geisler, W. J. Weninger, S. Geyer, J. Hewinson, N. A. Karp, Catherine L. Angela L. Cecilia Icoresi Emma Charlotte Diane Tudor Green Mazzeo Siragher Lillistone Gleeson Set, Catherine Tudor, Angela L. Green, C. Mazzeo, E. Siragher, Charlotte Lillistone, Diane Gleeson, Debarati Sethi, T. Bayzetinova, Jonathan Burvill, Bishoy Habib, Lauren Weavers, R. Maswood, Evelina Miklejewska, Michael Woods, E. Grau, Stuart Newman, Caroline Sinclair, Ellen Brown, B. Doe, A. Galli, Ramiro Ramírez-Solis, Edward Ryder, Karen Steel, Allan Bradley, W. Skarnes, D. J. Adams, D. Lafont, Valerie E. Vancollie, Robbie S. B. McLaren, Lena Hughes-Hallett, Christine Rowley, Emma Sanderson, E. Tuck, Monika Dąbrowska, M. Griffiths, David J. Gannon, Nicola Cockle, Andrea Kirton, Joanna Bottomley, Catherine Ingle, C. Lelliott, Jacqueline K. White, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. Rowland, C. Lelliott, M. Del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. Henssen, M. Rooimans, J. de Lange, T. Mohun, M. Arends, K. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. Perry, S. P. Jackson, G. Balmus   +86 more
semanticscholar   +1 more source

Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/3.0/), which
Aardema, Altenburger, Andreas Kortenkamp, Antoccia, Backhaus, Bentley, Berenbaum, Bianchi-Santamaria, Bliss, Bonatti, Castelain, Clare, COM., Davidse, Decordier, Diaz, Dolara, Drescher, Efron, EFSA., Elhajouji, Elhajouji, Ermler, Faust, Fellows, Fenech, Friedman, Graillot, Hashimoto, Hollomon, Kirkland, Kirsch-Volders, Kortenkamp, Loewe, Lorge, Lutz, Lutz, Marshall, Martin Scholze, Mosmann, OECD., Phelps, Ramírez, Ramírez, Santovito, Scholze, Sibylle Ermler, Sternes, Surrallés, Van Hummelen, Varga   +50 more
core   +1 more source

Chemical Composition and Toxicity of PM₁₀ and PM_0.1 Samples near Open-Pit Mines and Coal Power Stations

Life, 2022
Particulate matter (PM)
Aleksey Larionov, Valentin Volobaev, Anton Zverev, Evgeniya Vdovina, Sebastian Bach, Ekaterina Schetnikova, Timofey Leshukov, Konstantin Legoshchin, Galina Eremeeva   +8 more
doaj   +1 more source

In Vitro Mutagenic and Genotoxic Assessment of a Mixture of the Cyanotoxins Microcystin-LR and Cylindrospermopsin [PDF]

, 2019
The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different than those observed for single cyanotoxins, as interaction phenomena cannot be discarded. Moreover, mixtures are a more probable exposure scenario. However,
Cameán Fernández, Ana María, Díez-Quijada Jiménez, Leticia, Jos Gallego, Ángeles Mencía, Prieto Ortega, Ana Isabel, Puerto Rodríguez, María   +4 more
core   +1 more source

Evaluation of the antigenotoxic and antioxidant activity induced by Croton antisyphiliticus [PDF]

Anais da Academia Brasileira de Ciências, 2020
This study aimed to investigate antigenotoxicity and antioxidant potential of extract, fractions and vitexin from C. antisyphiliticus. Methanolic extract was fractionated through solvents of increasing polarity.
REGILDO M.G. DA SILVA, CÉLIA C.M. FIGUEIREDO, AMANDA C. GOMES, PAULO C. FERREIRA, FILIPE O. GRANERO, PATRÍCIA S. SANTIAGO, LUCIANA P. SILVA   +6 more
doaj   +1 more source

High throughput image cytometry micronucleus assay to investigate the presence or absence of mutagenic effects of cold physical plasma

Environmental and Molecular Mutagenesis, 2018
Promising cold physical plasma sources have been developed in the field of plasma medicine. An important prerequisite to their clinical use is lack of genotoxic effects in cells.
Sander Bekeschus, A. Schmidt, A. Kramer, H. Metelmann, Frank Adler, T. von Woedtke, Felix Niessner, K. Weltmann, K. Wende   +8 more
semanticscholar   +1 more source

Is There a Causal Association between Genotoxicity and the Imposex Effect? [PDF]

, 2006
There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Colborn T, Collins MKL, Cooke H, Depledge MH, Gibbs PE, Harring KE, Harris JO, Josephine A. Hagger, Jörg Oehlmann, Laruelle F, Michael H. Depledge, Smith BS, Susan Jobling, Tamara S. Galloway   +13 more
core   +2 more sources