Genotoxicity Evaluation of Capsaicin-Containing (CP) Pharmacopuncture, in an In Vivo Micronucleus Test. [PDF]
Hwang JH, Ku J, Jung C.
europepmc +1 more source
The Double Face of Base Excision Repair: Preventing and Triggering Double‐Strand Breaks
Base excision repair is conserved from bacteria to man, robustly eliminating oxidized bases in DNA and reinserting the appropriate nucleotide to restore an intact double helix. Recent results describe conditions and mechanisms that misregulate long‐patch BER to generate double‐strand breaks, triggering chromosome fragmentation and cell death, altering ...
Susan M. Gasser
wiley +1 more source
Application of micronucleus assay in plants to monitor environmental pollution in situ [PDF]
Samples of 5 vascular plant species: Achillea millefolium L., Artemisia vulgaris L., Festuca gigantea (L.) VILL., Ranunculus acris L. s. str. and Vicia angustifolia L. were collected near Fuel Storage Station, Chemical Fibre Factory “Wistom” in Tomaszów
Kośmider, Beata +2 more
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Genomic Instability in Buccal Mucosal Cells of Municipal Street Sweepers as Evaluated by Micronucleus Test [PDF]
Victor Hugo Pereira da Silva +7 more
openalex +1 more source
Genotoxicity evaluation of levonorgestrel-releasing intrauterine system (LNG-IUS) in exfoliated cervical cells using the micronucleus (MN) test [PDF]
Ayşe Gül Zamanı +4 more
openalex +1 more source
The study evaluates the phyto and cytogenotoxic activity of eight eugenol‐derived triazole compounds in Lactuca sativa. Compounds 2b and 2e exhibit high phytotoxicity, comparable to glyphosate, as well as cytotoxic and genotoxic effects associated with their greater hydrophilicity, highlighting them as promising candidates for the development of ...
Thayllon de Assis Alves +11 more
wiley +1 more source
Micronucleus test on gas station attendants.
In the present study, the micronucleus test was applied in exfoliated cells of buccal mucosa to assess the mutagenicity risk associated with occupational exposure for gas station attendants. For each individual, 2000 exfoliated buccal cells were analyzed for micronucleus frequency.
Cibelem Iribarrem, Benites +3 more
openaire +1 more source
Biosafety Evaluation of 6,7‐Dihydroxy‐3‐(2‐Nitrophenyl)Coumarin in Human Cells
ABSTRACT Coumarins are considered a privileged scaffold in medicinal chemistry, as they may interact with biological macromolecules, presenting several pharmacological properties. Their potential makes them an object of study for the evaluation of their safety for humans, which is essential in the design of a potential drug.
Júlia Zocca Nunes de Barros +3 more
wiley +1 more source
First approaches in the study of cytotoxic and mutagenic damage induced by cold aqueous extract of Baccharis articulata on normal cells [PDF]
Species of Genus Baccharis (Asteraceae) possess various bioactivities in vitro. The aim was to determine the cytogenotoxic activity of the cold aqueous extract (CAE) of Baccharis articulata.
Cariddi, Laura Noelia +5 more
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