Results 21 to 30 of about 13,726,259 (365)

Giemsa versus acridine orange staining in the fish micronucleus assay and validation for use in water quality monitoring [PDF]

open access: yes, 2011
This study concerns a comparative analysis of the acridineorange and Giemsastaining procedures for the fish erythrocyte micronucleusassay. The goal was to optimize the assay in the context of field watermonitoring. Fish (Carassius carassius) were exposed
Gauthier, Laury   +5 more
core   +2 more sources

Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation [PDF]

open access: yes, 2016
Background: Breast cancer risk increases drastically in individuals carrying a germline BRCA1 mutation. The exposure to ionizing radiation for diagnostic or therapeutic purposes of BRCA1 mutation carriers is counterintuitive, since BRCA1 is active in the
A Pijpe   +67 more
core   +4 more sources

Study of Genotoxicity, Activities on Caspase 8 and on the Stabilization of the Topoisomerase Complex of Isoeleutherin and Analogues

open access: yesMolecules, 2023
This study evaluated the genotoxicity of Ethanol Extract (EEEp), Dichloromethane Fraction (FDCMEp) and isoeleutherin isolated from Eleutherine plicata, using the micronucleus test and the impact of structural alterations on toxicity and molecular docking
Kelly Cristina Oliveira de Albuquerque   +9 more
doaj   +1 more source

Genotoxic and stress inductive potential of cadmium in Xenopus laevis larvae [PDF]

open access: yes, 2006
The present investigation evaluates the toxic potential of Cd in larvae of the frog Xenopus laevis after 12 days of exposure to environmentally relevant contamination levels, close to those measured in the river Lot (France).
Baudrimont, Magalie   +6 more
core   +3 more sources

Maximum tolerated doses and erythropoiesis effects in the mouse bone marrow by 79 pesticides’ technical materials assessed with the micronucleus assay

open access: yesToxicology Reports, 2019
Effects of technical materials of pesticide active ingredients, belonging to various chemical classes, on erythropoiesis in mouse bone marrow were studied as part of the research on the pesticide mutagenic activity in micronucleus test.
Nataliya Ilyushina   +9 more
doaj   +1 more source

Mutagenicity induced by the hydroalcoholic extract of the medicinal plant Plathymenia reticulata Benth

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2011
Plathymenia reticulata Benth has an anti-inflammatory effect and is capable of neutralizing the neuromuscular blockade induced by Bothrops jararacussu or Crotalus durissus terrificus venoms, probably by precipitating venom proteins (an effect caused by ...
A Della Torre   +11 more
doaj   +1 more source

The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]

open access: yes, 2010
Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel   +2 more
core   +2 more sources

Evaluation of the genotoxic and teratogenic potential of a municipal sludge and sludge-amended soil using the amphibian Xenopus laevis and the tobacco: Nicotiana tabacum L. var. xanthi Dulieu [PDF]

open access: yes, 2003
The toxic, genotoxic and teratogenicpotential of amunicipal sewage sludge was assessed using the micronucleus assay on the larvae of the amphibianXenopuslaevis and with the tobacco somatic mutation test using the yellow–green xanthiDulieu mutant a1+/a1 ...
Chenon, Pascale   +4 more
core   +4 more sources

ATR-FTIR spectroscopy detects alterations induced by organotin(IV) carboxylates in MCF-7 cells at sub-cytotoxic/-genotoxic concentrations. [PDF]

open access: yes, 2008
The environmental impact of metal complexes such as organotin(IV) compounds is of increasing concern. Genotoxic effects of organotin(IV) compounds (0.01 μg/ml, 0.1 μg/ml or 1.0 μg/ml) were measured using the alkaline single-cell gel electrophoresis ...
Ahmad, Muhammad S.   +6 more
core   +3 more sources

Investigation of Toxicity in Black Jaw Tilapia (Sarotherodon melanotheron) Exposed to Crude Oil [PDF]

open access: yesIranica Journal of Energy and Environment, 2020
The toxicity effects of crude oil were investigated in the laboratory. Triplicates of (T1) 0.25mg/l, (T2) 1.0mg/l, (T3) 2.25mg/l, (T4) 5.0mg/l and (T5) 7.5mg/l concentration of crude oil exposed to Sarotherodon melanotheron species.
S. O. Ayoola, C. E. Ejikeme, O. Folami
doaj   +1 more source

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