Giemsa versus acridine orange staining in the fish micronucleus assay and validation for use in water quality monitoring [PDF]
This study concerns a comparative analysis of the acridineorange and Giemsastaining procedures for the fish erythrocyte micronucleusassay. The goal was to optimize the assay in the context of field watermonitoring. Fish (Carassius carassius) were exposed
Gauthier, Laury +5 more
core +2 more sources
Increased chromosomal radiosensitivity in asymptomatic carriers of a heterozygous BRCA1 mutation [PDF]
Background: Breast cancer risk increases drastically in individuals carrying a germline BRCA1 mutation. The exposure to ionizing radiation for diagnostic or therapeutic purposes of BRCA1 mutation carriers is counterintuitive, since BRCA1 is active in the
A Pijpe +67 more
core +4 more sources
This study evaluated the genotoxicity of Ethanol Extract (EEEp), Dichloromethane Fraction (FDCMEp) and isoeleutherin isolated from Eleutherine plicata, using the micronucleus test and the impact of structural alterations on toxicity and molecular docking
Kelly Cristina Oliveira de Albuquerque +9 more
doaj +1 more source
Genotoxic and stress inductive potential of cadmium in Xenopus laevis larvae [PDF]
The present investigation evaluates the toxic potential of Cd in larvae of the frog Xenopus laevis after 12 days of exposure to environmentally relevant contamination levels, close to those measured in the river Lot (France).
Baudrimont, Magalie +6 more
core +3 more sources
Effects of technical materials of pesticide active ingredients, belonging to various chemical classes, on erythropoiesis in mouse bone marrow were studied as part of the research on the pesticide mutagenic activity in micronucleus test.
Nataliya Ilyushina +9 more
doaj +1 more source
Plathymenia reticulata Benth has an anti-inflammatory effect and is capable of neutralizing the neuromuscular blockade induced by Bothrops jararacussu or Crotalus durissus terrificus venoms, probably by precipitating venom proteins (an effect caused by ...
A Della Torre +11 more
doaj +1 more source
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]
Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel +2 more
core +2 more sources
Evaluation of the genotoxic and teratogenic potential of a municipal sludge and sludge-amended soil using the amphibian Xenopus laevis and the tobacco: Nicotiana tabacum L. var. xanthi Dulieu [PDF]
The toxic, genotoxic and teratogenicpotential of amunicipal sewage sludge was assessed using the micronucleus assay on the larvae of the amphibianXenopuslaevis and with the tobacco somatic mutation test using the yellow–green xanthiDulieu mutant a1+/a1 ...
Chenon, Pascale +4 more
core +4 more sources
ATR-FTIR spectroscopy detects alterations induced by organotin(IV) carboxylates in MCF-7 cells at sub-cytotoxic/-genotoxic concentrations. [PDF]
The environmental impact of metal complexes such as organotin(IV) compounds is of increasing concern. Genotoxic effects of organotin(IV) compounds (0.01 μg/ml, 0.1 μg/ml or 1.0 μg/ml) were measured using the alkaline single-cell gel electrophoresis ...
Ahmad, Muhammad S. +6 more
core +3 more sources
Investigation of Toxicity in Black Jaw Tilapia (Sarotherodon melanotheron) Exposed to Crude Oil [PDF]
The toxicity effects of crude oil were investigated in the laboratory. Triplicates of (T1) 0.25mg/l, (T2) 1.0mg/l, (T3) 2.25mg/l, (T4) 5.0mg/l and (T5) 7.5mg/l concentration of crude oil exposed to Sarotherodon melanotheron species.
S. O. Ayoola, C. E. Ejikeme, O. Folami
doaj +1 more source

