Evaluation of the novel liver micronucleus assay using formalin-fixed tissues
Genes and Environment, 2019 Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity.
Shuichi Hamada +12 more
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Investigation of Toxicity in Black Jaw Tilapia (Sarotherodon melanotheron) Exposed to Crude Oil [PDF]
Iranica Journal of Energy and Environment, 2020 The toxicity effects of crude oil were investigated in the laboratory. Triplicates of (T1) 0.25mg/l, (T2) 1.0mg/l, (T3) 2.25mg/l, (T4) 5.0mg/l and (T5) 7.5mg/l concentration of crude oil exposed to Sarotherodon melanotheron species.
S. O. Ayoola, C. E. Ejikeme, O. Folami
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Chronic ethanol consumption in mice does not induce DNA damage in somatic or germ cells, evaluated by the bone marrow micronucleous assay and the dominant lethal mutation assay [PDF]
, 2012 Indexación: Web of Science; ScieloAlthough alcohol is known to be a carcinogen for humans, ethanol-genotoxicity studies are incomplete. Ethanol seems not to be a bacterial mutagen, but the results are conflicting in rodent assays.
Ellahueñe, Manuel +2 more
core +1 more source
Genotoxicity assessment of piperitenone oxide: an in vitro and in silico evaluation [PDF]
, 2017 Piperitenone oxide, a natural flavouring agent also known as rotundifolone, has been studied for the genotoxicity assessment by an integrated in vitro and in silico experimental approach, including the bacterial reverse mutation assay, the micronucleus ...
Abete, Lorena +9 more
core +1 more source
Is there a causal association between genotoxicity and the imposex effect? [PDF]
, 2006 There is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones.
Josephine A. Hagger +13 more
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MICRONUCLEUS TEST IN MOST RECENT ICHTHIOLOGY RESEARCH [PDF]
Croatian Journal of Fisheries, 2005 The purpose of this paper was to give an insight into the most recent ichthiology research in which Micronucleus test is used. This test has been used for some time now as a tool for determining DNA damage in model–organism. Scientists have been using it
Vesna Mijat
doaj
Evaluation of genotoxicity through micronuclei test in workers of car and battery repair garages
Genetics and Molecular Biology, 2002 In this study, the micronuclei test (MNT) was applied in exfoliated cells of buccal mucosa, in order to evaluate the genotoxic risk associated with occupational exposure of mechanics, storage battery renovation workers, and car painters.
M.G. Martino-Roth +5 more
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In Vitro Mutagenic and Genotoxic Assessment of a Mixture of the Cyanotoxins Microcystin-LR and Cylindrospermopsin [PDF]
, 2019 The co-occurrence of various cyanobacterial toxins can potentially induce toxic effects different than those observed for single cyanotoxins, as interaction phenomena cannot be discarded. Moreover, mixtures are a more probable exposure scenario. However,
Cameán Fernández, Ana María +4 more
core +1 more source
Guidance on aneugenicity assessment
EFSA Journal, 2021 The EFSA Scientific Committee was asked to provide guidance on the most appropriate in vivo tests to follow up on positive in vitro results for aneugenicity, and on the approach to risk assessment for substances that are aneugenic but not clastogenic nor
EFSA Scientific Committee (SC) +29 more
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Salivary ki-67 and micronucleus assay as potential biomarker of OSCC in betel nut chewers
Journal of Indian Academy of Oral Medicine and Radiology, 2021 Introduction: Oral cancer is often associated with various factors, such as betel nut consumption, which usually causes specific premalignant lesions. The most common oral cancer is oral squamous cell carcinoma (OSCC) which has a low 5-year survivor rate
Maulina Triani +4 more
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