Results 121 to 130 of about 199,125 (144)

A prepared platelet‐rich plasma extract, namely Self‐Growth Colony, inhibits melanogenesis by down‐regulating microphthalmia‐associated transcription factor in skin melanocyte

Journal of Cosmetic Dermatology, 2021
During melanogenesis, melanocytes produce melanin through enzymatic reactions. Microphthalmia‐associated transcription factor (MITF) is a major regulator in controlling the expressions of melanogenic enzymes tyrosinase (TYR), tyrosine‐related protein‐1 ...
M. S. Guo, Qi-Yun Wu, Q. Lai, Xiaoyang Wang, Panzhu Bai, K. Fung, Tina T. X. Dong, K. Tsim   +7 more
semanticscholar   +1 more source

Hinokitiol-induced decreases of tyrosinase and microphthalmia-associated transcription factor are mediated by the endoplasmic reticulum-associated degradation pathway in human melanoma cells.

Biochimie, 2021
Tyrosinase (TYR) is a key enzyme for melanin production. We previously showed that hinokitiol, a naturally occurring seven-membered ring terpenoid, potently inhibits human TYR activity.
T. Oyama, Haruka Ogawa, Y. Shirai, H. Abe, T. Kamiya, Takehiko Abe, S. Tanuma   +6 more
semanticscholar   +1 more source

Licochalcone A restrains microphthalmia‐associated transcription factor expression and growth by activating autophagy in melanoma cells via miR‐142‐3p/Rheb/mTOR pathway

Phytotherapy Research, 2019
Licochalcone A (LCA) was found to possess anticancer effects. This study aimed to investigate the anticancer effects and mechanisms of LCA in melanoma. A375 and B16 melanoma cells were stimulated with LCA, MTT assay was used to assess cell proliferation.
Yuhong Zhang, Ming-Min Gao, Li Chen, Li-Juan Zhou, Shengnan Bian, Yong-Mei Lv   +5 more
semanticscholar   +1 more source

Identification of a gene encoding microphthalmia-associated transcription factor and its association with shell color in the clam Meretrix petechialis.

Comparative Biochemistry and Physiology Part B Comparative Biochemistry, 2018
The microphthalmia-associated transcription factor (MITF) is a master regulator of melanocyte development through the direct transcriptional control of related genes, e.g., the phenoloxidase gene.
Shujing Zhang, Hong-Xia Wang, Jiajia Yu, Feng-Juan Jiang, Xin Yue, Bao-Zhong Liu   +5 more
semanticscholar   +1 more source

Microphthalmia-associated transcription factor (MiTF): Promiscuous staining patterns in fibrohistiocytic lesions is a potential pitfall.

Pathology, Research and Practice, 2018
Microphthalmia-associated transcription factor (MiTF) is used as a marker of melanocytic differentiation. However, MiTF immunoexpression has also been observed in histiocytes, macrophages, smooth muscle cells and fibroblasts, which raise the concern of ...
S. Mohanty, Shivani Sharma, Dinesh Pradhan, S. Kandukuri, Navid Farahani, C. Barry, Julie M. Wu, D. Frishberg, Bonnie Balzer   +8 more
semanticscholar   +1 more source

The microphthalmia-associated transcription factor is involved in gastrointestinal stromal tumor growth

Cancer Gene Therapy, 2022
Elizabeth Proaño-Pérez, Eva Serrano-Candelas, A. García-Valverde, Jordi Rosell, D. Gómez-Peregrina, A. Navinés-Ferrer, M. Guerrero, C. Serrano, Margarita Martín   +8 more
semanticscholar   +1 more source

Knockout of microphthalmia-associated transcription factor (mitf) confers a red and yellow tilapia with few pigmented melanophores

Aquaculture, 2022
Chenxu Wang, T. Kocher, Jin-Zhi Wu, Pengfei Li, Guangyuan Liang, Bao-Yue Lu, Jia Xu, Xiaoke Chen, De-Shou Wang   +8 more
semanticscholar   +1 more source

A CRISPR-Cas12a-based electrochemical biosensor for the detection of microphthalmia-associated transcription factor

Microchimica Acta
Qisheng Luo, Chun-Yuan Zhang, Xiandong Deng, Dongyuan Liu, Xingchen Pan, Yuan-Xun Gong, Qian-Li Tang, Kai Zhang, Xian-Jiu Liao   +8 more
semanticscholar   +1 more source

Melanocytes and the Microphthalmia Transcription Factor Network

Annual Review of Genetics, 2004
Eirikur Steingrimsson, Neal G Copeland, Nancy A Jenkins   +2 more
exaly  

Microphthalmia Associated Transcription Factor Is a Target of the Phosphatidylinositol-3-Kinase Pathway

Journal of Investigative Dermatology, 2003
Corine Bertolotto, Robert Ballotti, Mehdi Khaled   +2 more
exaly