Results 111 to 120 of about 9,717,047 (191)

Mouse microphthalmia-associated transcription factor (Mitf) mutations affect the structure of the retinal vasculature. [PDF]

Acta Ophthalmol, 2022
Daníelsson SB, García-Llorca A, Reynisson H, Eysteinsson T.   +3 more
europepmc   +1 more source

Functional characterization of the transcription factor YjjQ in Escherichia coli [PDF]

, 2013
YjjQ is a FixJ/NarL‐type transcriptional regulator conserved in commensal and various pathogenic bacteria such as enterohaemorrhagic Escherichia coli (EHEC), uropathogenic E. coli (UPEC) as well as Citrobacter and Enterobacter.
Dreck, Katrin
core  

Transcriptional Regulation of the Beta-Synuclein 5′-Promoter Metal Response Element by Metal Transcription Factor-1 [PDF]

, 2011
The progression of many human neurodegenerative disorders is associated with an accumulation of alpha-synuclein. Alpha-synuclein belongs to the homologous synuclein family, which includes beta-synuclein.
Patrick C McHugh, David R. Brown, Josephine A. Wright, McHugh, Patrick C, Wright, Josephine A., Josephine A Wright, Wright Josephine A., Brown David R., David R Brown, McHugh Patrick C., Brown, David R., Patrick C. McHugh   +11 more
core   +1 more source

Emerging roles of MITF as a crucial regulator of immunity

Experimental and Molecular Medicine
Microphthalmia-associated transcription factor (MITF), a basic helix-loop-helix leucine zipper transcription factor (bHLH-Zip), has been identified as a melanocyte-specific transcription factor and plays a critical role in melanocyte survival ...
Aram Lee, Jihyun Lim, Jong-Seok Lim
doaj   +1 more source

Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling

Molecular Systems Biology, 2013
Genes with common profiles of the presence and absence in disparate genomes tend to function in the same pathway. By mapping all human genes into about 1000 clusters of genes with similar patterns of conservation across eukaryotic phylogeny, we ...
Yuval Tabach, Tamar Golan, Abrahan Hernández‐Hernández, Arielle R Messer, Tomoyuki Fukuda, Anna Kouznetsova, Jian‐Guo Liu, Ingrid Lilienthal, Carmit Levy, Gary Ruvkun   +9 more
doaj   +1 more source

SH3BP2 Silencing Increases miRNAs Targeting ETV1 and Microphthalmia-Associated Transcription Factor, Decreasing the Proliferation of Gastrointestinal Stromal Tumors. [PDF]

Cancers (Basel), 2022
Proaño-Pérez E, Serrano-Candelas E, Mancia C, Navinés-Ferrer A, Guerrero M, Martin M.   +5 more
europepmc   +1 more source

Growth Regulatory Proteins that Repress Differentiation Markers in Melanocytes Also Downregulate the Transcription Factor Microphthalmia [PDF]

, 1996
Expression of basic fibroblast growth factor cDNA or dominantly acting oncogenes, e.g., E1A, in immortalized mouse melanocytes leads to autonomous growth in vitro, depigmentation, and in the case of the oncogenes, tumorigenesis. Because downregulation of
Cheng, Elaine, Zhang, Yuhua, Halaban, Ruth, Moellmann, Gisela, Böhm, Markus, Dotto, Paolo   +5 more
core   +1 more source

Using temporal correlation in factor analysis for reconstructing transcription factor activities [PDF]

, 2008
Two-level gene regulatory networks consist of the transcription factors (TFs) in the top level and their regulated genes in the second level. The expression profiles of the regulated genes are the observed high-throughput data given by experiments such ...
Wernisch, Lorenz, Lorenz Wernisch, Pournara, Iosifina, Iosifina Pournara   +3 more
core   +1 more source

The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor. [PDF]

Int J Stem Cells, 2023
Shang Z, Feng H, Xia L.
europepmc   +1 more source

A transcriptional network underlies susceptibility to kidney disease progression

EMBO Molecular Medicine, 2012
The molecular networks that control the progression of chronic kidney diseases (CKD) are poorly defined. We have recently shown that the susceptibility to development of renal lesions after nephron reduction is controlled by a locus on mouse chromosome 6
Denise Laouari, Martine Burtin, Aurélie Phelep, Frank Bienaime, Laure‐Hélène Noel, David C. Lee, Christophe Legendre, Gérard Friedlander, Marco Pontoglio, Fabiola Terzi   +9 more
doaj   +1 more source