Results 91 to 100 of about 199,125 (144)

Emerging roles of MITF as a crucial regulator of immunity

Experimental and Molecular Medicine
Microphthalmia-associated transcription factor (MITF), a basic helix-loop-helix leucine zipper transcription factor (bHLH-Zip), has been identified as a melanocyte-specific transcription factor and plays a critical role in melanocyte survival ...
Aram Lee, Jihyun Lim, Jong-Seok Lim
doaj   +1 more source

A transcriptional network underlies susceptibility to kidney disease progression

EMBO Molecular Medicine, 2012
The molecular networks that control the progression of chronic kidney diseases (CKD) are poorly defined. We have recently shown that the susceptibility to development of renal lesions after nephron reduction is controlled by a locus on mouse chromosome 6
Denise Laouari, Martine Burtin, Aurélie Phelep, Frank Bienaime, Laure‐Hélène Noel, David C. Lee, Christophe Legendre, Gérard Friedlander, Marco Pontoglio, Fabiola Terzi   +9 more
doaj   +1 more source

The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor. [PDF]

Int J Stem Cells, 2023
Shang Z, Feng H, Xia L.
europepmc   +1 more source

Diarylpropionitrile inhibits melanogenesis via protein kinase A/cAMP-response element-binding protein/microphthalmia-associated transcription factor signaling pathway in α-MSH-stimulated B16F10 melanoma cells. [PDF]

Korean J Physiol Pharmacol, 2022
Lee HJ, An S, Bae S, Lee JH.
europepmc   +1 more source

Correction: Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells. [PDF]

J Immunother Cancer, 2023
europepmc   +1 more source

α-Mangostin, a safe and natural product as a candidate skin-whitening agent

Scientific Reports
A-Mangostin is the predominant xanthone found in the pericarp of mangosteen. It has been scientifically proven to possess anti-proliferative and apoptotic properties against different types of human cancer cells.
Xinmei Li, Xinyu Zhu, Bingqian Wang, Jiaming Sun, Yun Xia   +4 more
doaj   +1 more source

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology.

Laboratory investigation; a journal of technical methods and pathology, 2017
A. Kawakami, D. Fisher
semanticscholar   +1 more source

Microphthalmia-Associated Transcription Factor-Dependent Melanoma Cell Adhesion Molecule Activation Promotes Peritoneal Metastasis of Ovarian Cancer. [PDF]

Int J Mol Sci, 2020
Kitami K, Yoshihara M, Koya Y, Sugiyama M, Iyoshi S, Uno K, Mogi K, Tano S, Fujimoto H, Nawa A, Kikkawa F, Kajiyama H.   +11 more
europepmc   +1 more source

Anti-Melanogenic Effect of Dendropanax morbiferus and Its Active Components via Protein Kinase A/Cyclic Adenosine Monophosphate-Responsive Binding Protein- and p38 Mitogen-Activated Protein Kinase-Mediated Microphthalmia-Associated Transcription Factor Downregulation. [PDF]

Front Pharmacol, 2020
Park JU, Yang SY, Guo RH, Li HX, Kim YH, Kim YR.   +5 more
europepmc   +1 more source

A Novel Butyrate Derivative, Zinc Dibutyroyllysinate, Blunts Microphthalmia-Associated Transcription Factor Expression and Up-Regulates Retinol and Differentiation Pathway mRNAs in a Full-Thickness Human Skin Model. [PDF]

Int J Mol Sci
Swindell WR, Bojanowski K, Quijas G, Chaudhuri RK.   +3 more
europepmc   +1 more source