Results 101 to 110 of about 22,552 (272)

Investigating the Relationship between miR210 Upregulation and Hemoglobin Gamma Chain Expression

پیاورد سلامت, 2011
Background and Aim: Micro RNAs are a group of small non-coding RNAs which play an important role in multiple processes such as proliferation, differentiation, apoptosis, and cancer.
Seyed Amir Hossein Emami, Shahin Mohammadi, Saeed Kavyani, Masud Soleimani, Shaban Alizadeh, Ehteram Dejbakhsh, Fatemeh Kouhkan, Majid Mossahebi, Hossein Dargahi   +8 more
doaj  

Expression of exosomal microRNAs miR-34a and miR-210 in male infertility: relationship with morphokinetic parameters and sperm DNA fragmentation

Вестник урологии
Introduction. Infertility affects tens of millions of men and women across the globe. In approximately half of cases, male factors are the cause of infertility.
Sh. N. Galimov, E. F. Galimova, I. R. Gilyazova, I. D. Gromenko, Yu. Yu. Gromenko, D. D. Gromenko, K. Sh. Galimov, V. D. Kotenko, T. Z. Tkeshelashvili, G. R. Abdeeva, P. F. Litvitsky, V. N. Pavlov   +11 more
doaj   +1 more source

The Role of MicroRNA-210 in Esophageal Squamous Cell Carcinoma

YAKUGAKU ZASSHI, 2012
In this review, we summarize our findings on microRNA-210 (miR-210) and the target gene, and discuss their significance in human esophageal squamous cell carcinoma (ESCC). MicroRNAs are evolutionarily conserved small noncoding RNAs (20-23 nucleotides) that bind to complementary sequences in the 3' UTR of target mRNAs and regulate gene expression by the
openaire   +3 more sources

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

miR-210 Protects Renal Cell Against Hypoxia-induced Apoptosis by Targeting HIF-1 Alpha

Molecular Medicine, 2017
The kidney is vulnerable to hypoxia-induced injury. One of the mechanisms underlying this phenomenon is cell apoptosis triggered by hypoxia-inducible factor-1- α (HIF-1α) activation.
Li-Li Liu, Dahu Li, Yun-Ling He, Yan-Zhao Zhou, Sheng-Hui Gong, Li-Ying Wu, Yong-Qi Zhao, Xin Huang, Tong Zhao, Lun Xu, Kui-Wu Wu, Ming-Gao Li, Ling-Ling Zhu, Ming Fan   +13 more
doaj   +1 more source

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions [PDF]

Circulation Research, 2017
Rationale: In the search for markers and modulators of vascular disease, microRNAs (miRNAs) have emerged as potent therapeutic targets. Objective: To investigate miRNAs of clinical interest in patients with unstable carotid ...
Eken, Suzanne M., Jin, Hong, Chernogubova, Ekaterina, Li, Yuhuang, Simon, Nancy, Sun, Changyan, Korzunowicz, Greg, Busch, Albert, Bäcklund, Alexandra, Österholm, Cecilia, Razuvaev, Anton, Renné, Thomas, Eckstein, Hans Henning, Pelisek, Jaroslav, Eriksson, Per, González Díez, María, Perisic Matic, Ljubica, Schellinger, Isabel N., Raaz, Uwe, Leeper, Nicholas J., Hansson, Göran K., Paulsson-Berne, Gabrielle, Hedin, Ulf, Maegdefessel, Lars   +23 more
openaire   +3 more sources

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

miR-210 is essential to retinal homeostasis in fruit flies and mice

Biology Direct
Background miR-210 is one of the most evolutionarily conserved microRNAs. It is known to be involved in several physiological and pathological processes, including response to hypoxia, angiogenesis, cardiovascular diseases and cancer. Recently, new roles
Davide Colaianni, Federico Virga, Annamaria Tisi, Chiara Stefanelli, Germana Zaccagnini, Paola Cusumano, Gabriele Sales, Mihai Bogdan Preda, Fabio Martelli, Daniela Taverna, Massimiliano Mazzone, Cristiano Bertolucci, Rita Maccarone, Cristiano De Pittà   +13 more
doaj   +1 more source

Association of microRNAs and pathologic response to preoperative chemotherapy in triple negative breast cancer: preliminary report [PDF]

, 2014
Triple negative breast cancer (TNBC) has caught the attention of oncologists worldwide because of poor prognosis and paucity of targeted therapies. Gene pathways have been widely studied, but less is known about epigenetic factors such as microRNAs ...
Choi, Young Eun, Chowdhury, Dipanjan, Fendler, Wojciech, Kolacinska, Agnieszka, Kubiak, Robert, Malachowska, Beata, Morawiec, Jan, Morawiec, Zbigniew, Pakula, Lukasz, Pawlowska, Zofia, Szemraj, Janusz, Zawlik, Izabela   +11 more
core   +1 more source