Results 31 to 40 of about 21,599 (235)

MicroRNA-210 promotes angiogenesis in acute myocardial infarction

Molecular Medicine Reports, 2018
MicroRNA-210 (miRNA-210) has been reported to be associated with angiogenesis and may serve important roles in acute myocardial infarction (AMI), which remain unclear. The present study sought to evaluate the efficacy of miRNA‑210 in AMI and to examine the potential associated mechanisms. AMI models were established in Sprague‑Dawley rats.
Fan, Zhong-Guo, Qu, Xin-Liang, Chu, Peng, Gao, Ya-Li, Gao, Xiao-Fei, Chen, Shao-Liang, Tian, Nai-Liang   +6 more
openaire   +3 more sources

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells.

PLoS ONE, 2015
Expression and regulation of microRNAs is an emerging issue in erythroid differentiation and globin gene expression in hemoglobin disorders. In the first part of this study microarray analysis was performed both in mithramycin-induced K562 cells and ...
Nicoletta Bianchi, Alessia Finotti, Manuela Ferracin, Ilaria Lampronti, Cristina Zuccato, Giulia Breveglieri, Eleonora Brognara, Enrica Fabbri, Monica Borgatti, Massimo Negrini, Roberto Gambari   +10 more
doaj   +1 more source

Plasma microRNA levels following resection of metastatic melanoma [PDF]

, 2017
Melanoma remains the leading cause of skin cancer–related deaths. Surgical resection and adjuvant therapies can result in disease-free intervals for stage III and stage IV disease; however, recurrence is common.
Abrams, Zachary B, Agnese, Doreen, Carson III, William E, Fadda, Paolo, Howard, J. Harrison, Jacob, Naduparambil, Latchana, Nicholas, Markowitz, Joseph, Payne, Philip, Regan, Kelly, Terando, Alicia   +10 more
core   +3 more sources

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions [PDF]

Circulation Research, 2017
Rationale: In the search for markers and modulators of vascular disease, microRNAs (miRNAs) have emerged as potent therapeutic targets. Objective: To investigate miRNAs of clinical interest in patients with unstable carotid ...
Eken, Suzanne M., Jin, Hong, Chernogubova, Ekaterina, Li, Yuhuang, Simon, Nancy, Sun, Changyan, Korzunowicz, Greg, Busch, Albert, Bäcklund, Alexandra, Österholm, Cecilia, Razuvaev, Anton, Renné, Thomas, Eckstein, Hans Henning, Pelisek, Jaroslav, Eriksson, Per, González Díez, María, Perisic Matic, Ljubica, Schellinger, Isabel N., Raaz, Uwe, Leeper, Nicholas J., Hansson, Göran K., Paulsson-Berne, Gabrielle, Hedin, Ulf, Maegdefessel, Lars   +23 more
openaire   +3 more sources

Potential role of HIF-1-responsive microRNA210/HIF3 axis on gemcitabine resistance in cholangiocarcinoma cells. [PDF]

PLoS ONE, 2018
MicroRNA-210 (miR-210) is a robust target for hypoxia-inducible factor, and its overexpression has been detected in a variety of solid tumors. However, the role of miR-210 in the development, progression and response to therapy in cholangiocarcinoma (CCA)
Runglawan Silakit, Yingpinyapat Kitirat, Suyanee Thongchot, Watcharin Loilome, Anchalee Techasen, Piti Ungarreevittaya, Narong Khuntikeo, Puangrat Yongvanit, Ji Hye Yang, Nam Hee Kim, Jong In Yook, Nisana Namwat   +11 more
doaj   +1 more source

Impact of Hypoxia-Induced miR-210 on Pancreatic Cancer

Current Issues in Molecular Biology, 2023
Pancreatic cancer (PC) poses significant clinical challenges, with late-stage diagnosis and limited therapeutic options contributing to its dismal prognosis.
Mutian Lian, Maria Mortoglou, Pinar Uysal-Onganer   +2 more
doaj   +1 more source

Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo

Molecular Therapy: Nucleic Acids, 2018
We previously found that 19 microRNAs (miRNAs) significantly increased in the sera of hepatocellular carcinoma (HCC) patients. Here, we evaluated whether these miRNAs were secreted by HCC cells and contributed to tumor angiogenesis. High level of miR-210-
Xue-Jia Lin, Jian-Hong Fang, Xiao-Jing Yang, Chong Zhang, Yunfei Yuan, Limin Zheng, Shi-Mei Zhuang   +6 more
doaj   +1 more source

MicroRNA-210 and endoplasmic reticulum chaperones in the regulation of chemoresistance in glioblastoma [PDF]

, 2015
Glioblastoma multiforme (GBM) is the commonest primary brain tumour in adults characterized by relentless recurrence due to resistance towards the standard chemotherapeutic agent temozolomide (TMZ).
Fung, CF, Ho, ASW, Kiang, KMY, Lee, D, Leung, GKK, Lui, WM, Sun, S, Zhang, PD, Zhang, XQ   +8 more
core   +1 more source

MicroRNA‐210 Decreases heme Levels by Targeting Ferrochelatase in Cardiomyocytes [PDF]

Journal of the American Heart Association, 2013
Background Micro RNA ‐210 (miR‐210) increases in hypoxia and regulates mitochondrial respiration through modulation of iron‐sulfur cluster assembly proteins ( ISCU 1/2), a protein that is involved in Fe/S cluster synthesis.
Qiao, Aijun, Khechaduri, Arineh, Kannan Mutharasan, R., Wu, Rongxue, Nagpal, Varun, Ardehali, Hossein   +5 more
openaire   +2 more sources

Phoenix dactylifera L. sap enhances wound healing in Wistar rats : Phytochemical and histological assessment [PDF]

, 2016
Acknowledgment Financial support of the Tunisian Ministry of Higher Education and Scientific Research is gratefully acknowledged.Peer ...
Abdennabi, Raed, Alenezi, Faizah N., Bardaa, Sana, Belbahri, Lassaad, Gharsallah, Neji, Mehdi, Meriem, Raab, Andrea, Rateb, Mostafa E., Sahnoun, Zouheir   +8 more
core   +3 more sources