Impact of Hypoxia-Induced miR-210 on Pancreatic Cancer
Current Issues in Molecular Biology, 2023 Pancreatic cancer (PC) poses significant clinical challenges, with late-stage diagnosis and limited therapeutic options contributing to its dismal prognosis.
Mutian Lian +2 more
doaj +1 more source
Various levels of circulating exosomal total-miRNA and miR-210 hypoxamiR in different forms of pregnancy hypertension [PDF]
, 2017 K
Alasztics, Bálint +5 more
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Role of microRNA-210 in human intervertebral disc degeneration
Experimental and Therapeutic Medicine, 2016 The present study aimed to investigate the role of microRNA (miR)-210 in the development of intervertebral disc degeneration (IDD). Human nucleus pulposus (NP) samples were collected from patients with scoliosis and IDD (n=12 each) as the scoliosis control and IDD groups, respectively.
DA-Ying, Zhang +4 more
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Intact feto-placental growth in microRNA-210 deficient mice [PDF]
Placenta, 2016 MicroRNA-210 (miR-210) has been implicated in homeostatic adaptation during hypoxia. We hypothesized that miR-210 deficiency impacts feto-placental growth. As expected, mir-210 knockout (ko) mice exhibited markedly reduced placental miR-210 expression, compared to wild-type (wt) mice.
Kamil Krawczynski +3 more
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Post-ischaemic immunological response in the brain: targeting microglia in ischaemic stroke therapy [PDF]
, 2020 Microglia, the major endogenous immune cells of the central nervous system, mediate critical degenerative and regenerative responses in ischaemic stroke.
Chen, Ruoli +4 more
core +3 more sources
PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells [PDF]
, 2014 PLC-beta 1 (PLCβ1) inhibits in human K562 cells erythroid differentiation induced by mithramycin (MTH) by targeting miR-210 expression. Inhibition of miR-210 affects the erythroid differentiation pathway and it occurs to a greater extent in MTH-treated ...
Bavelloni, Alberto +9 more
core +5 more sources
MicroRNA-210 promotes angiogenesis in acute myocardial infarction
Molecular Medicine Reports, 2018 MicroRNA-210 (miRNA-210) has been reported to be associated with angiogenesis and may serve important roles in acute myocardial infarction (AMI), which remain unclear. The present study sought to evaluate the efficacy of miRNA‑210 in AMI and to examine the potential associated mechanisms. AMI models were established in Sprague‑Dawley rats.
Fan, Zhong-Guo +6 more
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Pregnancy-associated cardiac dysfunction and the regulatory role of microRNAs. [PDF]
, 2020 Many crucial cardiovascular adaptations occur in the body during pregnancy to ensure successful gestation. Maladaptation of the cardiovascular system during pregnancy can lead to complications that promote cardiac dysfunction and may lead to heart ...
Aryan, Laila +3 more
core
MicroRNAs in melanoma development and resistance to target therapy [PDF]
, 2017 microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio +7 more
core +1 more source
Effects of microRNA‑210 on the diagnosis and treatment of prostate cancer
Molecular Medicine Reports, 2018 The present study aimed to investigate the effects of microRNA-210 (miR-210) in the diagnosis and treatment of prostate cancer. Venous blood was collected from 30 prostate cancer patients, that were treated in the Medical Group of Ping Mei Shenma General Hospital (Pingdingshan, China) from June 2013 to May 2015, and 20 healthy men.
Yuejun, Qu, Wenqiang, Huang
openaire +3 more sources