Results 71 to 80 of about 22,552 (272)

miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]

open access: yes, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria   +6 more
core   +1 more source

MicroRNA-210-3p Targets RGMA to Enhance the Angiogenic Functions of Endothelial Progenitor Cells Under Hypoxic Conditions

open access: yesFrontiers in Cellular Neuroscience, 2019
Endothelial progenitor cells (EPCs) are multipotential stem cells considered to have immense clinical value for revascularization. However, the clinical application of EPCs has been hampered by their clinical potency in ischemic anoxic environments. This
Wen-Jing Lu   +9 more
doaj   +1 more source

Plasma microrna expression profile for reduced ejection fraction in dilated cardiomyopathy

open access: yesScientific Reports, 2021
The left ventricular (LV) ejection fraction (EF) is key to prognosis in dilated cardiomyopathy (DCM). Circulating microRNAs have emerged as reliable biomarkers for heart diseases, included DCM.
Maria Calderon-Dominguez   +7 more
doaj   +1 more source

MicroRNA-210 negatively regulates the radiosensitivity of nasopharyngeal carcinoma cells

open access: bronzeMolecular Medicine Reports, 2017
Radiotherapy is one of the primary methods of treatment of malignant tumors, however, resistance to radiation is a major problem. The reasons for the radioresistance are still poorly understood. However, it is generally accepted that microRNAs (miRNAs or miRs) can regulate the radiosensitivity of tumors.
Boyi Li   +6 more
openalex   +5 more sources

Quantification of microRNA-210 in the cerebrospinal fluid and serum: Implications for Alzheimer’s disease

open access: diamondExperimental and Therapeutic Medicine, 2015
The aim of the present study was to investigate the potential clinical application of the genetic marker microRNA (miRNA)-210 in the cerebrospinal fluid (CSF) and serum of patients with Alzheimer's disease (AD). The enrolled patients were divided into the mild cognitive impairment (MCI) and AD groups. Healthy individuals were used as the controls.
Yan Zhu   +4 more
openalex   +5 more sources

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma [PDF]

open access: yes, 2017
The most common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC). It accounts for 70-80% of all renal malignancies representing the third most common urological cancer after prostate and bladder cancer.
Carbone, Antonio   +12 more
core   +2 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Potential role of HIF-1-responsive microRNA210/HIF3 axis on gemcitabine resistance in cholangiocarcinoma cells.

open access: yesPLoS ONE, 2018
MicroRNA-210 (miR-210) is a robust target for hypoxia-inducible factor, and its overexpression has been detected in a variety of solid tumors. However, the role of miR-210 in the development, progression and response to therapy in cholangiocarcinoma (CCA)
Runglawan Silakit   +11 more
doaj   +1 more source

Silencing of microRNA-210 inhibits the progression of liver cancer and hepatitis B virus-associated liver cancer via targeting EGR3

open access: yesBMC Medical Genetics, 2020
Background This study was aimed to investigate the regulatory role of microRNA-210 (miRNA-210) on the progression of liver cancer and Hepatitis B virus (HBV)-associated liver cancer.
Xiaojie Li, Mei Yuan, Lu Song, Yan Wang
doaj   +1 more source

MicroRNAs mediate metabolic stresses and angiogenesis [PDF]

open access: yes, 2011
MicroRNAs are short endogenous RNA molecules that are able to regulate (mainly inhibiting) gene expression at the post-transcriptional level. The MicroRNA expression profile is cell-specific, but it is sensitive to perturbations produced by stresses and ...
Patella, Francesca, Rainaldi, Giuseppe
core   +1 more source

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