Results 61 to 70 of about 21,064 (212)

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

MicroRNA-210 as a novel blood biomarker in acute cerebral ischemia

Frontiers in Bioscience, 2011
MicroRNA-210 (miR-210), a master and pleiotropic hypoxia-microRNA, plays multiple roles in brain ischemia. However, miR-210 expression and its function in humans have not been explored. The aim of our study is to evaluate the correlation of blood miR-210 with clinical findings in acute ischemic stroke.
Lili, Zeng, Jianrong, Liu, Yongting, Wang, Ling, Wang, Suiqing, Weng, Yaohui, Tang, Chaobo, Zheng, Qi, Cheng, Shengdi, Chen, Guo-Yuan, Yang   +9 more
openaire   +2 more sources

Acute hypoxia induces upregulation of microRNA-210 expression in glioblastoma spheroids [PDF]

CNS Oncology, 2015
Tumor hypoxia and presence of tumor stem cells are related to therapeutic resistance and tumorigenicity in glioblastomas. The aim of the present study was therefore to identify microRNAs deregulated in acute hypoxia and to identify possible associated changes in stem cell markers.Glioblastoma spheroid cultures were grown in either 2 or 21% oxygen ...
Rosenberg, Tine Agerbo, Thomassen, Mads, Jensen, Stine Skov, Larsen, Martin Jakob, Sørensen, Kristina Pilekær, Hermansen, Simon Kjær, Kruse, Torben A, Kristensen, Bjarne Winther   +7 more
openaire   +3 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Hypoxia-regulated MicroRNA-210 in neuronal plasticity [PDF]

, 2018
In recent years increasing evidence has established microRNAs as critical regulators of neuronal development and plasticity that can act locally, in an activity-dependent manner. The hypoxia-regulated microRNA-210 (miR-210) is a highly conserved miRNA, widely studied for its role in regulating cellular response to low oxygen conditions. Previously, our
openaire   +3 more sources

MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Pre‐eclampsia is a serious pregnancy‐related syndrome lacking accurate prognostic markers. MicroRNA‐210, overexpressed in the circulation of women with pre‐eclampsia, has recently emerged as a promising biomarker. Objectives We conducted a systematic review and meta‐analysis to evaluate the relationship between miR‐210 levels and ...
Dávid Márai, Isabel Pinto Amorim das Virgens, Ádám Vincze, Mahmoud Obeidat, Péter Hegyi, Mikolt Bakony, Zsófia Réka Erdélyi, Zsolt Melczer, Sándor Valent   +8 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Investigating the Relationship between miR210 Upregulation and Hemoglobin Gamma Chain Expression

پیاورد سلامت, 2011
Background and Aim: Micro RNAs are a group of small non-coding RNAs which play an important role in multiple processes such as proliferation, differentiation, apoptosis, and cancer.
Seyed Amir Hossein Emami, Shahin Mohammadi, Saeed Kavyani, Masud Soleimani, Shaban Alizadeh, Ehteram Dejbakhsh, Fatemeh Kouhkan, Majid Mossahebi, Hossein Dargahi   +8 more
doaj  

Expression of exosomal microRNAs miR-34a and miR-210 in male infertility: relationship with morphokinetic parameters and sperm DNA fragmentation

Вестник урологии
Introduction. Infertility affects tens of millions of men and women across the globe. In approximately half of cases, male factors are the cause of infertility.
Sh. N. Galimov, E. F. Galimova, I. R. Gilyazova, I. D. Gromenko, Yu. Yu. Gromenko, D. D. Gromenko, K. Sh. Galimov, V. D. Kotenko, T. Z. Tkeshelashvili, G. R. Abdeeva, P. F. Litvitsky, V. N. Pavlov   +11 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source