Results 61 to 70 of about 22,552 (272)

Investigating the Relationship Between MiR210 Upregulation and Hemoglobin Gamma Chain Expression [PDF]

پیاورد سلامت, 2012
Background and Aim: Micro RNAs are a group of small non-coding RNAs which play an important role in multiple processes such as proliferation, differentiation, apoptosis, and cancer.
Fatemeh Kouhkan, Ehteram Dejbakhsh, Saban Alizadeh, Masud Soleimani, Saeed Kavyani, Shahin Mohammadi, Seyed Amir Hossein Emami, Majid Mossahebi, Hossein Dargahi   +8 more
doaj  

Acceleration of healing of the medial collateral ligament of the knee by local administration of synthetic microRNA-210 in a rat model

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, 2015
Background: Injury to the medial collateral ligament (MCL) of the knee joint is the most common ligament injury of the knee. Ligament healing generally takes a long time.
Muhammad Sakti, Tomoyuki Nakasa, Takeshi Shoji, Muhammad Andry Usman, Yoshitaka Kawanishi, Michio Hamanishi, Irawan Yusuf, Mitsuo Ochi   +7 more
doaj   +1 more source

ROD1 is a seedless target gene of hypoxia-induced miR-210. [PDF]

PLoS ONE, 2012
Most metazoan microRNA (miRNA) target sites have perfect pairing to the "seed" sequence, a highly conserved region centering on miRNA nucleotides 2-7.
Pasquale Fasanaro, Sveva Romani, Christine Voellenkle, Biagina Maimone, Maurizio C Capogrossi, Fabio Martelli   +5 more
doaj   +1 more source

miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner

Biomedicines, 2021
Apoptotic cell death of cardiomyocytes is a characteristic hallmark of ischemia–reperfusion (I/R) injury. The master hypoxamiR, microRNA-210 (miR-210), is considered the primary driver of the cellular response to hypoxic stress.
Gurdeep Marwarha, Øystein Røsand, Nathan Scrimgeour, Katrine Hordnes Slagsvold, Morten Andre Høydal   +4 more
doaj   +1 more source

Down-regulation of TIMP2 by HIF-1α/miR-210/HIF-3α regulatory feedback circuit enhances cancer metastasis in hepatocellular carcinoma [PDF]

, 2016
Cancer metastasis is a multistep process that involves a series of tumor-stromal interaction, including extracellular matrix (ECM) remodeling, which requires a concerted action of multiple proteolytic enzymes and their endogenous inhibitors.
Chan, LK, Kai, AKL, Lee, MF, Lo, CLR, Ng, IOL, Wong, CCL, Wong, CM   +6 more
core   +1 more source

Downregulation of miR-210 Promoted Apoptosis of Hippocampal Neurons by Negatively Regulating the TLR4/NF-кB1 Signaling Pathway in a Rat Model of Status Epilepticus

Neuropsychiatric Disease and Treatment, 2022
Qin Zhou,1 Huanjun Luo,2 Xiaowei Wang,2 Peng Li,3 Haibo Kong,1 Baomei He1 1Center for Reproductive Medicine, Department of Pediatrics, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, People’s ...
Zhou Q, Luo H, Wang X, Li P, Kong H, He B   +5 more
doaj  

MicroRNA-210 expression during childbirth and postpartum as a potential biomarker of acute fetal hypoxia

Biomedical Papers, 2019
Objective: To explore whether miR-210 expression can be used as a diagnostic and prognostic marker in acute fetal hypoxia. Methods: Whole blood samples of 29 women and their fetuses without hypoxia and 24 women and their fetuses with hypoxia were ...
Barbara Vonkova, Ivona Blahakova, Lukas Hruban, Petr Janku, Sarka Pospisilova   +4 more
doaj   +1 more source

miRNAs link metabolic reprogramming to oncogenesis [PDF]

, 2013
The most profound biochemical phenotype of cancer cells is their ability to metabolize glucose to lactate, even under aerobic conditions. This alternative metabolic circuitry is sufficient to support the biosynthetic and energy requirements for cancer ...
Hatziapostolou, M, Iliopoulos, D, Polytarchou, C   +2 more
core   +1 more source

Roles of hypoxia-inducible microRNA-210 in hepatocellular carcinoma

, 2013
Hepatocellular carcinoma (HCC) is the fifth most prevalent human malignancy and the third leading cause of cancer deaths in the world. MicroRNAs (miRNA) are conserved, small noncoding RNA molecules that regulate gene expression of protein-coding gene posttranscriptionally.
Alan Kai Ka-lun
openalex   +3 more sources

miR-210: fine-tuning the hypoxic response [PDF]

, 2014
Hypoxia is a central component of the tumor microenvironment and represents a major source of therapeutic failure in cancer therapy. Recent work has provided a wealth of evidence that noncoding RNAs and, in particular, microRNAs, are significant members ...
A Allegra, A Giannakakis, A Hüttenhofer, A Krek, A Shinohara, A Ventura, A Zhao, AC Koong, AE Pasquinelli, AM Cheng, AS Ho, B Malzkorn, B Wightman, BE Baysal, BJ Reinhart, BL Pineles, BP Lewis, BP Lewis, C Camps, C Devlin, C Nakada, C-C Chio, CH Lawrie, D Baek, D Betel, D Gou, D Hanahan, D Juan, DA Enquobahrie, DA Landau, DD Taylor, DP Bartel, DP Bartel, DS Schwarz, E Balsa, E Bostjancic, E Fabbri, E Fabbri, E Favaro, E Gottlieb, E Miko, E Rooij van, EJ Jung, F Mochel, F Rothe, F Wu, FE Benson, FV Karginov, G Leone, G Meroni, G Wan, GA Calin, GL Semenza, GL Semenza, GL Semenza, GL Semenza, GL Wang, GL Wang, GL Wang, H Antonicka, H Guo, H Iguchi, H Valadi, H Zhang, H-Y Chen, HE Gee, HW Kim, HW Kim, HW King, I Satzger, J Brugarolas, J He, J Lu, J Sarkar, J Stenvang, J Tabernero, J Wang, JA Foekens, JA Lees, JA Weber, JC Presti Jr, JC Venter, JD Gordan, JM Brown, JR Gnarra, JW Kim, K Jeyaseelan, K Pulkkinen, K Ruan, KP Porkka, L Cicchillitti, L Hong, L Qin, L Salmena, LP Lim, M Ivan, M Kertesz, M Liu, M Maragkakis, M Raponi, M Redova, M Selbach, MA Alaiti, MA Cortez, MA Valencia-Sanchez, ME Crosby, MP Murphy, MP Puissegur, MV Iorio, MV Iorio, MZ Michael, N Bushati, N Yanaihara, NC Denko, NC Denko, NL Simone, NMA White, O Bunoust, P Fasanaro, P Fasanaro, P Fasanaro, P Jaakkola, P Vaupel, PJ Hurlin, PS Mitchell, R Bindra, R Faraonio, R Gambari, R Garzon, R Kulshreshtha, R Kulshreshtha, RA Gatenby, RB Donker, RC Lee, RD Guzy, RE Lanford, RF Place, RK Mutharasan, S Biswas, S Djebali, S Djuranovic, S Djuranovic, S Gilad, S Greco, S Griffiths-Jones, S Hammer, S Hu, S Krick, S Kuijper, S Tsuchiya, S Vasudevan, S Wang, SA Ciafre, SY Chan, T Greither, T Greither, T Kawamata, T Li, T Thum, T Toyama, TJ Kelly, W Yang, W Zundel, WH Tong, WR Wilson, X Chen, X Huang, X Huang, X Zhang, XM Zhu, Y Lee, Y Lee, Y Liu, Y Liu, Y Mizuno, Y Murakami, Y Nakamura, Y Nie, YL Lou, Z Chen, Z Zhang   +180 more
core   +1 more source