Results 41 to 50 of about 661,223 (352)

Identification of an allatostatin C signaling system in mollusc Aplysia

open access: yesScientific Reports, 2022
Neuropeptides, as pervasive intercellular signaling molecules in the CNS, modulate a variety of behavioral systems in both protostomes and deuterostomes.
Hui-Min Jiang   +15 more
doaj   +1 more source

MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs [PDF]

open access: yes, 2016
Medulloblastoma (MB) is the most common malignant brain tumor of pediatric age and is characterized by cells expressing stem, astroglial, and neuronal markers.
Alfano, Vincenzo   +13 more
core   +4 more sources

ING5 suppresses breast cancer progression and is regulated by miR-24

open access: yesMolecular Cancer, 2017
Background The inhibitor of growth (ING) gene family of tumor suppressors is involved in multiple cellular functions such as cell cycle regulation, apoptosis, and chromatin remodeling.
Shufang Cui   +10 more
doaj   +1 more source

LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

open access: yesMolecular Therapy: Nucleic Acids, 2020
Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and progression as critical regulators, while their potential roles in ...
Xiangfeng Meng   +8 more
doaj   +1 more source

Characterization of an Aplysia vasotocin signaling system and actions of posttranslational modifications and individual residues of the ligand on receptor activity

open access: yesFrontiers in Pharmacology, 2023
The vasopressin/oxytocin signaling system is present in both protostomes and deuterostomes and plays various physiological roles. Although there were reports for both vasopressin-like peptides and receptors in mollusc Lymnaea and Octopus, no precursor or
Ju-Ping Xu   +15 more
doaj   +1 more source

Detection of MicroRNAs in Dried Serum Blots [PDF]

open access: yes, 2010
MicroRNAs are short RNAs which can be utilized as biomarkers for a variety of conditions. They are detectable in serum, and changes in the levels of circulating microRNAs have been associated with different diseases.
Reema Mallick   +2 more
core   +2 more sources

Viral infection and neurological disorders—potential role of extracellular nucleotides in neuroinflammation

open access: yesExRNA, 2019
Neuroinflammation can be induced under several conditions including pathogen infection such as virus. As the main immune cells in brain, microglia activation plays a pivotal role in neuroinflammation by responding to the invading pathogens (viral DNA/RNA)
Liang Li   +4 more
doaj   +1 more source

Human cytomegalovirus-encoded microRNAs expression profile in plasma of patients with aortic dissection

open access: yesJournal of Cardiothoracic Surgery, 2023
Background Aortic dissection (AD) is a rare disease with high mortality for which no effective diagnostic biomarkers are available. Human cytomegalovirus (HCMV) infection is an important cause of the occurrence and progression of many diseases, but the ...
Yongqing Cheng   +8 more
doaj   +1 more source

MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]

open access: yes, 2012
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Cauchi, Michael   +2 more
core   +1 more source

Networks of intergenic long-range enhancers and snpRNAs drive castration-resistant phenotype of prostate cancer and contribute to pathogenesis of multiple common human disorders [PDF]

open access: yes, 2011
Biological and mechanistic relevance of intergenic disease-associated genetic loci (IDAGL) containing highly statistically significant disease-linked SNPs remains unknown. Here we present the experimental and clinical evidence revealing important role of
Anna Glinskii   +8 more
core   +2 more sources

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