Results 41 to 50 of about 471,948 (340)

MicroRNAs in the stressed heart: Sorting the signal from the noise [PDF]

open access: yes, 2014
The short noncoding RNAs, known as microRNAs, are of undisputed importance in cellular signaling during differentiation and development, and during adaptive and maladaptive responses of adult tissues, including those that comprise the heart.
Matkovich, Scot J
core   +3 more sources

MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]

open access: yes, 2012
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Cauchi, Michael   +2 more
core   +1 more source

MicroRNAs and autoimmunity [PDF]

open access: yesCurrent Opinion in Immunology, 2012
The role of microRNAs (miRNAs) in the regulation of many physiological and pathological processes has been intensely studied in recent years. Some miRNAs, such as miR-146a and miR-182, play a dominant role in the regulation of the innate and adaptive immune responses, respectively.
A. Ceribelli, M. Satoh, E. K. Chan
openaire   +2 more sources

Acute responses of circulating microRNAs to low-volume sprint interval cycling

open access: yesFrontiers in Physiology, 2015
Low-volume high-intensity interval training is an efficient and practical method of inducing physiological responses in various tissues to develop physical fitness and may also change the expression of circulating microRNAs (miRNAs).
Shu Fang eCui   +10 more
doaj   +1 more source

Vascular microRNAs

open access: yesCurrent Drug Targets, 2010
MicroRNAs are endogenously expressed small non-coding RNAs that regulate gene expression on the posttranscriptional level. During the last years microRNAs have emerged as key regulators of several physiological and pathophysiological processes in the vascular wall.
Angelika Bonauer   +2 more
openaire   +3 more sources

Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16

open access: yesNature Communications, 2016
Visceral adiposity is associated with metabolic diseases, whereas subcutaneous adiposity is comparatively benign. Here, the authors report that subcutaneous adipose tissue adopts visceral-like characteristics in response to prolonged fasting, and show ...
Hanying Ding   +12 more
doaj   +1 more source

Identification of three elevenin receptors and roles of elevenin disulfide bond and residues in receptor activation in Aplysia californica

open access: yesScientific Reports, 2023
Neuropeptides are ubiquitous intercellular signaling molecules in the CNS and play diverse roles in modulating physiological functions by acting on specific G-protein coupled receptors (GPCRs). Among them, the elevenin signaling system is now believed to
Ping Fu   +14 more
doaj   +1 more source

Reduced brain UCP2 expression mediated by microRNA-503 contributes to increased stroke susceptibility in the high-salt fed stroke-prone spontaneously hypertensive rat [PDF]

open access: yes, 2017
UCP2 maps nearby the lod score peak of STR1-stroke QTL in the SHRSP rat strain. We explored the potential contribution of UCP2 to the high-salt diet (JD)-dependent increased stroke susceptibility of SHRSP.
Baima, Simona   +15 more
core   +1 more source

Co-regulatory network of transcription factor and microrna: A key player of gene regulation

open access: yesBiomedical and Biotechnology Research Journal, 2021
Transcription factor (TF) and microRNA (miRNA) interaction plays a vital role in the regulation of biological networks. TFs and miRNAs control the gene expression: TF at transcriptional level by affecting the messenger RNA (mRNA) transcription and miRNA ...
Akshara Pande
doaj   +1 more source

Regulation of neutrophil senescence by microRNAs [PDF]

open access: yes, 2011
Neutrophils are rapidly recruited to sites of tissue injury or infection, where they protect against invading pathogens. Neutrophil functions are limited by a process of neutrophil senescence, which renders the cells unable to respond to chemoattractants,
A Bonauer   +60 more
core   +4 more sources

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