Results 51 to 60 of about 645,948 (387)

Reduced brain UCP2 expression mediated by microRNA-503 contributes to increased stroke susceptibility in the high-salt fed stroke-prone spontaneously hypertensive rat [PDF]

open access: yes, 2017
UCP2 maps nearby the lod score peak of STR1-stroke QTL in the SHRSP rat strain. We explored the potential contribution of UCP2 to the high-salt diet (JD)-dependent increased stroke susceptibility of SHRSP.
Baima, Simona   +15 more
core   +1 more source

Fasting induces a subcutaneous-to-visceral fat switch mediated by microRNA-149-3p and suppression of PRDM16

open access: yesNature Communications, 2016
Visceral adiposity is associated with metabolic diseases, whereas subcutaneous adiposity is comparatively benign. Here, the authors report that subcutaneous adipose tissue adopts visceral-like characteristics in response to prolonged fasting, and show ...
Hanying Ding   +12 more
doaj   +1 more source

miRBase: integrating microRNA annotation and deep-sequencing data

open access: yesNucleic Acids Res., 2010
miRBase is the primary online repository for all microRNA sequences and annotation. The current release (miRBase 16) contains over 15 000 microRNA gene loci in over 140 species, and over 17 000 distinct mature microRNA sequences.
Ana Kozomara, S. Griffiths-Jones
semanticscholar   +1 more source

Vascular microRNAs

open access: yesCurrent Drug Targets, 2010
MicroRNAs are endogenously expressed small non-coding RNAs that regulate gene expression on the posttranscriptional level. During the last years microRNAs have emerged as key regulators of several physiological and pathophysiological processes in the vascular wall.
Angelika Bonauer   +2 more
openaire   +3 more sources

MicroRNAs in the stressed heart: Sorting the signal from the noise [PDF]

open access: yes, 2014
The short noncoding RNAs, known as microRNAs, are of undisputed importance in cellular signaling during differentiation and development, and during adaptive and maladaptive responses of adult tissues, including those that comprise the heart.
Matkovich, Scot J
core   +3 more sources

MicroRNAs and autoimmunity [PDF]

open access: yesCurrent Opinion in Immunology, 2012
The role of microRNAs (miRNAs) in the regulation of many physiological and pathological processes has been intensely studied in recent years. Some miRNAs, such as miR-146a and miR-182, play a dominant role in the regulation of the innate and adaptive immune responses, respectively.
A. Ceribelli, M. Satoh, E. K. Chan
openaire   +2 more sources

Geometric Mean of 5S rRNA and MiR-16 As A Suitable Normalizer In Esophageal Cancer [PDF]

open access: yesJournal of Cell and Molecular Research, 2016
Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with poor prognosis. In this regard, early diagnosis is of vital importance to cure the tumor in its early stages.
Samaneh Khazaei   +2 more
doaj   +1 more source

Regulation of neutrophil senescence by microRNAs [PDF]

open access: yes, 2011
Neutrophils are rapidly recruited to sites of tissue injury or infection, where they protect against invading pathogens. Neutrophil functions are limited by a process of neutrophil senescence, which renders the cells unable to respond to chemoattractants,
A Bonauer   +60 more
core   +4 more sources

The microRNA Registry [PDF]

open access: yesNucleic Acids Research, 2004
The miRNA Registry provides a service for the assignment of miRNA gene names prior to publication. A comprehensive and searchable database of published miRNA sequences is accessible via a web interface (http://www.sanger.ac.uk/Software/Rfam/mirna/), and all sequence and annotation data are freely available for download.
openaire   +4 more sources

microRNA Bioinformatics

open access: yesCells, 2022
Firstly, I apologize for the delayed publication of this Special Issue in the form of a book title [...]
openaire   +3 more sources

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