Results 51 to 60 of about 282,025 (323)
Exploration of Targeted Anti-tumor Therapy, 2022 Head and neck squamous cell carcinomas (HNSCCs) represent the most common epithelial tumors that arise from mucosa of the oral cavity, pharynx, and larynx.
Mariana Chantre-Justino +2 more
doaj +1 more source
Quantitative Modelling of Diffusion-driven Pattern Formation in microRNA-regulated Gene Expression [PDF]
arXiv, 2023 MicroRNAs are extensively known for post-transcriptional gene regulation and pattern formation in the embryonic developmental stage. We explore the origin of these spatio-temporal patterns mathematically, considering three different motifs here.
arxiv
The role of incoherent microRNA-mediated feedforward loops in noise buffering [PDF]
PLoS Comput Biol. (2011) 7(3):e1001101, 2010 MicroRNAs are endogenous non-coding RNAs which negatively regulate the expression of protein-coding genes in plants and animals. They are known to play an important role in several biological processes and, together with transcription factors, form a complex and highly interconnected regulatory network.
arxiv +1 more source
Pre-microRNA and Mature microRNA in Human Mitochondria
PLoS ONE, 2011 Because of the central functions of the mitochondria in providing metabolic energy and initiating apoptosis on one hand and the role that microRNA (miRNA) play in gene expression, we hypothesized that some miRNA could be present in the mitochondria for post-transcriptomic regulation by RNA interference.
Barrey, Eric +5 more
openaire +10 more sources
Dynamical modeling of microRNA action on the protein translation process [PDF]
BMC Systems Biology 2010, 4 (1):13
http://www.biomedcentral.com/1752-0509/4/13, 2009 Protein translation is a multistep process which can be represented as a cascade of biochemical reactions (initiation, ribosome assembly, elongation, etc.), the rate of which can be regulated by small non-coding microRNAs through multiple mechanisms. It remains unclear what mechanisms of microRNA action are most dominant: moreover, many experimental ...
arxiv +1 more source
MicroRNAs and Osteoarthritis [PDF]
Cells, 2018 An imbalance in gene expressional events skewing chondrocyte anabolic and catabolic pathways toward the latter causes an aberrant turnover and loss of extracellular matrix proteins in osteoarthritic (OA) articular cartilage. Thus, catabolism results in the elevated loss of extracellular matrix proteins.
openaire +4 more sources
Cells, 2022 Firstly, I apologize for the delayed publication of this Special Issue in the form of a book title [...]
openaire +3 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Role and mechanism of microRNAs in oral lichen planus
口腔疾病防治, 2020 Oral lichen planus (OLP) is a chronic inflammatory disease of the mucosa, some of which will develop into oral squamous cell carcinoma (OSCC). However, the pathogenesis of OLP remains unknown, but autoimmunity has been suggested as a potential cause ...
YANG Yijie, GE Shuyun
doaj +1 more source
Bone & Joint Research, 2022 Aims: Alcoholism is a well-known detrimental factor in fracture healing. However, the underlying mechanism of alcohol-inhibited fracture healing remains poorly understood.
Daoyu Zhu +8 more
doaj +1 more source