Regulation of MicroRNA Biogenesis
The FASEB Journal, 2009 MicroRNAs (miRNAs) play key roles in diverse pathways in eukaryotes, and the dysregulation of miRNA biogenesis is often associated with human diseases. Biogenesis of canonical miRNAs is initiated by RNA polymerase II‐mediated transcription.
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Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
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Structural basis of microRNA biogenesis by Dicer-1 and its partner protein Loqs-PB. [PDF]
Mol Cell, 2022 Jouravleva K +6 more
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Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface
Plant Biotechnology Journal, EarlyView.ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng +8 more
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The relationship between prognosis of patients with traumatic brain injury and microRNA biogenesis proteins. [PDF]
Ulus Travma Acil Cerrahi Derg, 2023 Çabukusta Acar A +4 more
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Circular RNAs in Lotus japonicus Responses to Nutrient Supply and Mesorhizobium Symbiosis
Plant, Cell &Environment, EarlyView.ABSTRACT Symbiotic interactions between legumes and rhizobia enable nitrogen fixation under low nutrient conditions. The establishment and function of symbiotic interactions require coordinated changes in gene expression in both the host and the microbe. Circular RNAs (circRNAs) are endogenous gene‐specific molecules that can regulate transcription and
Delecia Utley +3 more
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Polymorphism rs3742330 in microRNA Biogenesis Gene DICER1 Is Associated with Pseudoexfoliation Glaucoma in Saudi Cohort. [PDF]
Genes (Basel), 2022 Kondkar AA +7 more
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Understanding exosomes in regenerative dentistry
Periodontology 2000, EarlyView.Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
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MicroRNA biogenesis and activity in plant cell dedifferentiation stimulated by cell wall removal. [PDF]
BMC Plant Biol, 2022 Dełeńko K +9 more
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Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
The Journal of Physiology, EarlyView.Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
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