Results 11 to 20 of about 580,775 (413)
Journal of Allergy and Clinical Immunology, 2018 MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial regulators of gene expression and promising candidates for biomarker development.
Thomas X. Lu, Marc E. Rothenberg
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MicroRNA: MicroRNAs Reach out into Dendrites [PDF]
Current Biology, 2006 A recent study has shown that miR-134, a brain-specific microRNA, is present in dendrites where it represses the local synthesis of the protein kinase LimK1; this is a novel form of translational regulation in dendrites and may have important physiological implications.
Tai, H., Schuman, E.
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MicroRNA or Not MicroRNA? [PDF]
, 2011 The avalanche of next generation sequencing data has led to a rapid increase of annotated microRNAs in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection of the current version of miRBase shows that dozens of entries conflict with other ncRNAs, in particular snoRNAs.With few exceptions ...
Steve Hoffmann +5 more
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The Effect of Composol Medium on miR-16 Expression during Platelet Storage up to Day 7 at Room Temperature [PDF]
Cell Journal, 2021 Objective: MicroRNAs (miRNAs) are short, noncoding RNAs that play vital roles in gene regulation. It has been shown that storage has an effect on platelet miRNAs.
Ali Rajabi +4 more
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MicroRNAs in Neurotoxicity [PDF]
Journal of Toxicology, 2012 MicroRNAs are gaining importance as regulators of gene expression with the capability to fine-tune and modulate cellular events. The complex network with their selective targets (mRNAs/genes) pave way for regulation of many physiological processes.
Kaur, P, Armugam, A, Jeyaseelan, K
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Identification of copper (Cu) stress-responsive grapevine microRNAs and their target genes by high-throughput sequencing [PDF]
Royal Society Open Science, 2019 MicroRNAs (miRNAs) are a class of single-stranded non-coding small RNAs (sRNAs) that are 20–24 nucleotides (nt) in length. Extensive studies have indicated that miRNAs play important roles in plant growth, development and stress responses.
Songtao Jiu +8 more
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Journal of Extracellular Vesicles, 2020 Retinal degeneration (RD) is one of the most common causes of visual impairment and blindness and is characterized by progressive degeneration of photoreceptors.
Baishijiao Bian +13 more
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MicroRNAs in Development [PDF]
TSW Development & Embryology, 2006 Over 10 years ago, the lab of Victor Ambros cloned an unusual gene,lin-4, which encodes two small RNA transcripts[1]. In the past few years, hundreds more of these tiny transcripts, termed microRNAs (miRNAs), have been uncovered in over a dozen species.
Danielle M. Maatouk, Brian D. Harfe
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Modulation of microRNA Activity by Semi-microRNAs [PDF]
Frontiers in Genetics, 2012 The ribonuclease Dicer plays a central role in the microRNA pathway by catalyzing the formation of 19-24-nucleotide (nt) long microRNAs. Subsequently incorporated into Argonaute 2 (Ago2) effector complexes, microRNAs are known to regulate messenger RNA (mRNA) translation.
Preethi H. Gunaratne +6 more
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Preliminary evidence supports circulating microRNAs as prognostic biomarkers for type 2 diabetes. [PDF]
, 2017 Background:Circulating microRNAs are emerging as potential prognostic biomarkers for the development of type 2 diabetes. However, microRNAs are also associated with complications from impaired glucose metabolism (e.g. endothelial cell function).
Allen, IE +5 more
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