Results 31 to 40 of about 580,775 (413)
Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis [PDF]
Open Biology, 2019 MicroRNAs (miRNAs) are one abundant class of small, endogenous non-coding RNAs, which regulate various biological processes by inhibiting expression of target genes.
Bing Chen +7 more
doaj +1 more source
Sex-biased expression of microRNAs in Drosophila melanogaster [PDF]
Marco A (2014) Open Biology 4, 140024, 2013 Most animals have separate sexes. The differential expression of gene products, in particular that of gene regulators, is underlying sexual dimorphism. Analyses of sex-biased expression have focused mostly in protein coding genes. Several lines of evidence indicate that microRNAs, a class of major gene regulators, are likely to have a significant role ...
arxiv +1 more source
Detecting new microRNAs in human osteoarthritic chondrocytes identifies miR-3085 as a human, chondrocyte-selective, microRNA [PDF]
, 2015 Objective: To use deep sequencing to identify novel microRNAs in human osteoarthritic cartilage which have a functional role in chondrocyte phenotype or function.
Aigner +59 more
core +1 more source
International Journal of General Medicine, 2021 Diming Zhao,1 Yilin Liu,2 Zhenqiang Xu,3,4 Hechen Shen,1 Shanghao Chen,1 Shijie Zhang,1 Yi Li,1 Haizhou Zhang,3,4 Chengwei Zou,3,4 Xiaochun Ma3,4 1Department of Cardiovascular Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong ...
Zhao D +9 more
doaj
Drug Delivery, 2020 Although microRNAs (miRNAs)-based cancer therapy strategies have been proved to be efficient and superior to chemotherapeutic agents in certain extent, the unstable properties of miRNAs significantly impaired the wide application.
Xin Liu +9 more
doaj +1 more source
Change Profiles and Functional Targets of MicroRNAs in Type 2 Diabetes Mellitus Patients with Obesity [PDF]
Diabetes & Metabolism Journal, 2023 Background MicroRNAs (miRNAs) exert an essential contribution to obesity and type 2 diabetes mellitus (T2DM). This study aimed to investigate the differences of miRNAs in the presence and absence of T2DM in patients with obesity, as well as before and ...
Guanhua Lu +5 more
doaj +1 more source
Exercise training attenuates diabetes-induced cardiac injury through increasing miR-133a and improving pro-apoptosis/anti-apoptosis balance in ovariectomized rats [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): The useful and effective role of exercise program to prevent cardiac tissue apoptosis and fibrosis in ovariectomized type 2 diabetic (T2DM) rats (OVR.D) is well known.
Parisa Habibi +4 more
doaj +1 more source
Intrinsic noise of microRNA-regulated genes and the ceRNA hypothesis [PDF]
PLoS ONE 8(8): e72676 (2013), 2012 MicroRNAs are small noncoding RNAs that regulate genes post-transciptionally by binding and degrading target eukaryotic mRNAs. We use a quantitative model to study gene regulation by inhibitory microRNAs and compare it to gene regulation by prokaryotic small non-coding RNAs (sRNAs).
arxiv +1 more source
Circulating microRNA, secreted microRNA and exogenous plant microRNA [PDF]
Journal of Translational Medicine, 2012 Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in the serum and plasma of humans and other animals such as mice, rats, bovine fetuses, calves and horses.
openaire +2 more sources
MicroRNAs and Metastasis [PDF]
Cancers, 2019 Metastasis, the development of secondary malignant growths at a distance from the primary site of a cancer, is associated with almost 90% of all cancer deaths, and half of all cancer patients present with some form of metastasis at the time of diagnosis. Consequently, there is a clear clinical need for a better understanding of metastasis.
Charles H. Lawrie +2 more
openaire +3 more sources