Results 31 to 40 of about 283,349 (198)

MicroRNAs as Potential Liquid Biopsy Biomarker for Patients with Castration-Resistant Prostate Cancer

open access: yesResearch and Reports in Urology, 2022
Nicolas Fernandez,1 Julian Chavarriaga,2 Paola Ayala,3 Adriana Pedraza,4 John Bolivar,5 Juan Guillermo Prada,6 Juan Guillermo Cataño,6 Herney Garcia,7 Juliana Villanueva,6 Daniela Varela,6 Ignacio Zarante3 1Division of Urology Seattle Children’s Hospital,
Fernandez N   +10 more
doaj  

MicroRNAs in atherosclerosis

open access: yesThe Kaohsiung Journal of Medical Sciences, 2012
AbstractMicroRNAs are endogenously expressed small noncoding RNAs that regulate gene expression at the post‐transcriptional level. MicroRNAs have emerged as key regulators of several physiological and pathophysiological processes in the cardiovascular system.
Ku Chung Chen, Suh-Hang Hank Juo
openaire   +4 more sources

Identification of key microRNAs involved in tumorigenesis and prognostic microRNAs in breast cancer

open access: yesMathematical Biosciences and Engineering, 2020
Breast cancer is a commonly diagnosed cancer in women, and one of the leading causes of cancer-related death among female patients However, the key microRNAs involved in its tumorigenesis and microRNAs of prognostic values have not been fully understood.
Dongchen Lu, Wei Han, Kai Lu
doaj   +1 more source

Comparative evaluation of microRNA-155 expression level and its correlation with tumor necrotizing factor α and interleukin 6 in patients with chronic periodontitis

open access: yesDental Research Journal, 2022
Background: MicroRNAs are a class of small noncoding ribonucleic acids that perform a critical role in adjustment of gene expression. miRNAs-155 (miR-155) participates in controlling inflammation.
Ahmad Mogharehabed   +3 more
doaj   +1 more source

Regulation of Cardiac MicroRNAs by Cardiac MicroRNAs [PDF]

open access: yesCirculation Research, 2013
Rationale: MicroRNAs modestly suppress their direct mRNA targets, and these direct effects are amplified by modulation of gene transcription pathways. Consequently, indirect mRNA modulatory effects of microRNAs to increase or decrease mRNAs greatly outnumber direct target suppressions.
Scot J. Matkovich   +2 more
openaire   +2 more sources

Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): Chronic kidney disease (CKD), accompanied by renal dysfunction, fibrosis, and apoptosis, is highly prevalent in postmenopausal women. We tested the hypothesis that isoflavone daidzein may ameliorate renal dysfunction and fibrosis through ...
Majid Askaripour   +9 more
doaj   +1 more source

miRNAs as Interconnectors between Obesity and Cancer

open access: yesNon-Coding RNA
Obesity and cancer are a concern of global interest. It is proven that obesity may trigger the development or progression of some types of cancer; however, the connection by non-coding RNAs has not been totally explored. In the present review, we discuss
Grecia Denisse González-Sánchez   +4 more
doaj   +1 more source

The epigenetics of diabetes, obesity, overweight and cardiovascular disease

open access: yesAIMS Genetics, 2019
The objectives of this review were once to understand the roles of the epigenetics mechanism in different types of diabetes, obesity, overweight, and cardiovascular disease. Epigenetics represents a phenomenon of change heritable phenotypic expression of
Harem Othman Smail
doaj   +1 more source

Mammalian microRNAs predominantly act to decrease target mRNA levels

open access: yesNature, 2010
MicroRNAs (miRNAs) are endogenous ∼22-nucleotide RNAs that mediate important gene-regulatory events by pairing to the mRNAs of protein-coding genes to direct their repression.
Huili Guo   +3 more
semanticscholar   +1 more source

Vascular microRNAs

open access: yesCurrent Drug Targets, 2010
MicroRNAs are endogenously expressed small non-coding RNAs that regulate gene expression on the posttranscriptional level. During the last years microRNAs have emerged as key regulators of several physiological and pathophysiological processes in the vascular wall.
Angelika Bonauer   +2 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy