Results 181 to 190 of about 48,754 (308)

Species‐Specific Genetic Patterns in Sympatric Freshwater Turtles Challenge a Generalized Multi‐Species Conservation Approach

open access: yesAnimal Conservation, EarlyView.
We compared genetic diversity and spatial genetic structure in the snapping turtle (Chelydra serpentina; left panel), Blanding's turtle (Emydoidea blandingii; bottom right), and spotted turtle (Clemmys guttata; top right) sampled in areas of co‐occurrence across ~49,160 km2.
Christina M. Davy   +3 more
wiley   +1 more source

Genotyping Contemporary Captive and Historical Wild Western Lowland Gorillas Indicates Captive Breeding Is Maintaining Genetic Diversity in a Critically Endangered Primate

open access: yesAnimal Conservation, EarlyView.
Captive populations of threatened species risk losing genetic diversity over time. We evaluated the genetic status of contemporary captive western lowland gorillas (Gorilla gorilla gorilla) at Howletts and Port Lympne and compared this with specimens from a historical wild population.
Jaimie Morris   +5 more
wiley   +1 more source

Genomic Assessment of Reintroduced African Wild Dogs Informs Conservation Translocations

open access: yesAnimal Conservation, EarlyView.
Few reintroduction and translocation programs incorporate genomic assessments into management planning, despite ongoing debate over how founder individuals should be selected. Here, we assess the genomic composition of reintroduced African wild dog (Lycaon pictus) populations in private reserves in South Africa, comparing them with a free‐roaming ...
Michou Weimar   +4 more
wiley   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski   +7 more
wiley   +1 more source

Genetic diversity, population structure, and drug resistance of Plasmodium falciparum in Kenya: a systematic review and meta-analysis. [PDF]

open access: yesMalar J
Nyataya JN   +6 more
europepmc   +1 more source

Impact of RAS/RAF Mutations on Metastatic Treatment Response Following Total Neoadjuvant Therapy in Patients With Stage IV Rectal Cancer

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
There is limited understanding of the impact of underlying RAS/RAF mutational status on total neoadjuvant therapy metastatic tumor response rates in curative Stage IV rectal cancer patients. Complete metastatic tumor response to TNT was demonstrated in half as many mRAS as wtRAS patients and disease progression was higher in patients harboring RAS ...
Tracy R. Fitzsimmons   +8 more
wiley   +1 more source

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