Results 191 to 200 of about 48,754 (308)

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source

Effects of the Ecuadorian Andes on genetic structure of the spectacled bear with new genetic datasets. [PDF]

Sci Rep
Ruiz-García M, Castellanos A, Árias-Vásquez JY, Shostell JM.   +3 more
europepmc   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Behavioral and Historical Processes Jointly Maintain Genetic Connectivity in Fragmented Chinese Water Deer Populations. [PDF]

Ecol Evol
Li Z, Liu P, Zhang Z, Chen J, Liu Z, Teng L.   +5 more
europepmc   +1 more source

What Is the Evidence Base Regarding Early Onset Colorectal Cancer in Australia and New Zealand? A Scoping Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Early onset colorectal cancer (EoCRC), commonly defined as colorectal cancer diagnosed in people under 50 years of age, is increasing in incidence in Australia and New Zealand. The underlying cause of this remains unclear, despite its growing public health importance.
Tiffany J. Cherry, Dilshan Udayasiri, Ian P. Hayes   +2 more
wiley   +1 more source

Polymorphic microsatellite loci from ddRAD sequencing data in different Indian yak populations adapted to diverse climatic conditions. [PDF]

BMC Genomics
Ahmad SF, Chand R, Gangwar M, Rudhreswaran M, Kumar A, Hassan MM, Kumar ST, Kumar P, Kumar A, Dutt T.   +9 more
europepmc   +1 more source

Two Decades of Multimodal Management of Colorectal Liver Metastases With Long‐Term Outcomes

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background The management of patients with colorectal liver metastases (CRLM) is complex and requires a tailored approach based on disease extent, patient age, and comorbidities. Given the heterogeneity in presentation and evolving treatment algorithms, prognostic factors for long‐term survival following liver resection are contested.
Ali Mohtashami, Prajwol Shrestha, Sharon Chen, Jean‐Luc Vrisakis, Nazim Bhimani, Nick Pavlakis, Stephen J. Clarke, Connie I. Diakos, Matthew Wong, Thomas J. Hugh   +9 more
wiley   +1 more source

Prognostic Value of Non-nodal Regional Metastases in Predicting Sentinel Lymph Node Status in Cutaneous Melanoma: Multicenter Analysis of the Sentinel Lymph Node Working Group Database. [PDF]

Ann Surg Oncol
Riaz N, Leong SP, Kashani-Sabet M, White RL, Vetto JT, Schneebaum S, O'Donoghue C, Howard JH, Avisar E, Namm JP, Kosiorek H, Pockaj B, Faries M, Karakousis G, Zager JS, Olofsson Bagge R.   +15 more
europepmc   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Melanoma microsatellites exhibit a metastatic signature by spatial transcriptomics and overexpress mediators of immune evasion. [PDF]

Virchows Arch
Warren SJ, Xue GR, Zhou HM, Alomari AK, Turner MJ.   +4 more
europepmc   +1 more source