Results 111 to 120 of about 26,828 (241)

Micrometer‐Sized Liposome‐Based Systems: A Hierarchical Breakdown

open access: yesChemSystemsChem, EarlyView.
Micrometer‐sized liposomes (MSLs) are gaining attention for various applications, from biophysical cell models to molecular robots. Despite their growing importance, reviews on MSLs across disciplines are scarce. This review fills the gap by providing a systematic overview of MSL design, from applications to functionalization and to formation, aimed at
Shogo Hamada   +9 more
wiley   +1 more source

Assay for the terminal enzyme of the stearoyl coenzyme A desaturase system using chick embryo liver microsomes

open access: yesJournal of Lipid Research, 1977
The NADH-dependent stearoyl CoA desaturase of hepatic microsomes (EC 1.14.99.5) is an enzyme system consisting of cytochrome b5 reductase (EC 1.6.2.2), cytochrome b5, and the terminal desaturase. We have developed a simple method for routine assay of the
V C Joshi, A C Wilson, S J Wakil
doaj  

Pediatric Autoimmune Pancreatitis: Clinical Findings and Outcomes in Sweden

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Pediatric autoimmune pancreatitis (AIP) is a rare form of pancreatitis in children with poorly understood pathophysiology. It is a recognized risk factor for chronic pancreatitis in approximately 4% of pediatric cases. This study aims to describe the demographics, clinical characteristics, and outcomes of a large Swedish cohort of
Miroslav Vujasinovic   +9 more
wiley   +1 more source

Sidedness of ceramide-phosphoethanolamine synthesis on rat liver and brain microsomal membranes.

open access: yesJournal of Lipid Research, 1987
Phosphatidylethanolamine:ceramide-ethanolamine-phosphotransferase catalyzes the synthesis of ceramide-phosphoethanolamine, a sphingomyelin analogue. Its localization was studied in rat liver and brain microsomes.
M Malgat, A Maurice, J Baraud
doaj  

Gut Microbiota Regulate Lipid Metabolism via the Bile Acid Pathway: Resistance to Hypoxia in Gansu Zokor (Eospalax cansus)

open access: yesIntegrative Zoology, EarlyView.
The gut microbiota regulates lipid metabolism of Gansu zokor (Eospalax cansus) through the bile acid pathway in hypoxic environments, reflecting the unique survival strategy of subterranean rodents to maintain lipid metabolism homeostasis and flexible energy metabolism in hypoxic environments.
Maohong Yang   +5 more
wiley   +1 more source

Involvement of cytochrome P450 2E1 in the (ω–1)-hydroxylation of oleic acid in human and rat liver microsomes

open access: yesJournal of Lipid Research, 1998
In vitro techniques have been used to investigate the nature of microsomal cytochrome P450 involved in the metabolism of oleic acid, a physiological monounsaturated fatty acid. Like lauric acid, which is cur rently used as a model substrate of fatty acid
Fadi Adas   +5 more
doaj  

Electrocardiogram-based diagnosis of liver diseases: an externally validated and explainable machine learning approach [PDF]

open access: yesarXiv
Background: Liver diseases are a major global health concern, often diagnosed using resource-intensive methods. Electrocardiogram (ECG) data, widely accessible and non-invasive, offers potential as a diagnostic tool for liver diseases, leveraging the physiological connections between cardiovascular and hepatic health.
arxiv  

A New Cytochrome in Liver Microsomes

open access: yesJournal of Biological Chemistry, 1962
Ryo Sato, Tsuneo Omura
openaire   +3 more sources

A Xanthine Derivative With Novel Heat Shock Protein 90‐Alpha Inhibitory and Senolytic Properties

open access: yesAging Cell, EarlyView.
This study aimed to find safe senolytic drugs that selectively eliminate senescent cells. Focusing on HSP90 inhibitors, we employed a virtual screening to identify novel, safer compounds (A). K5, a xanthinic candidate, effectively eliminated senescent cells in various cellular models (B), extended lifespan in flies, and reduced aging signs in mice (C).
Sandra Atlante   +24 more
wiley   +1 more source

Top-K Maximum Intensity Projection Priors for 3D Liver Vessel Segmentation [PDF]

open access: yesarXiv
Liver-vessel segmentation is an essential task in the pre-operative planning of liver resection. State-of-the-art 2D or 3D convolution-based methods focusing on liver vessel segmentation on 2D CT cross-sectional views, which do not take into account the global liver-vessel topology.
arxiv  

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