Nucleotide Activation of Liver Microsomal Glucuronidation
Journal of Biological Chemistry, 1961 6 páginas en ...
Pogell, Burton M., Leloir, Luis Federico
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Journal of Traditional Chinese Medical Sciences, 2019 Objective: To explore the glucuronic acid metabolism of acacetin in human liver and intestinal microsomes to better characterize human uridine 5′-diphospho (UDP)-glucuronosyltransferase (UGT) isoforms. In addition, interspecies comparisons were performed
Kangle Shi, Shan Li, Qinggang Meng
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Qualification of Human Liver Microsomes for Antibacterial Activity Screening of Drug Metabolites
Applied Microbiology, 2023 Microsomes are commonly used to perform in vitro drug metabolism, predominantly to form phase I drug metabolites. Pooled microsomes from multiple donors can contain microorganisms from underlying microbial diseases.
Navid Jubaer
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Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]
, 1971 Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W. +50 more
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Dataset from proteomic analysis of human liver, lung, kidney and intestine microsomes
Data in Brief, 2018 We provide detailed datasets from our analysis of proteins that are identified in human liver, lung, kidney and intestine microsomes by MS-based proteomics.
Wei Song, Longjiang Yu, Zhihong Peng
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Regulation of hydroxymethylglutaryl-CoA reductase in rat leukocytes
Journal of Lipid Research, 1977 Methods were developed for the assay of hydroxymethylglutaryl-CoA reductase (NADPH) activity in microsomes from rat leukocytes. The activity in freshly isolated leukocytes is low compared to rat liver but can be assayed reliably. The patterns of response
N L Young, V W Rodwell
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Study on In Vitro Metabolism and In Vivo Pharmacokinetics of Beauvericin
Toxins, 2022 Beauvericin (BEA) is a well-known mycotoxin produced by many fungi, including Beaveria bassiana. The purpose of this study was to evaluate the in vitro distribution and metabolism characteristics as well as the in vivo pharmacokinetic (PK) profile of BEA.
Yu Yuan +3 more
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Journal of Lipid Research, 1980 Benzo(a)pyrene injection increased the phospholipid content in membranes of rat liver mitochondria and microsomes. There was a large relative increase of phosphatidylcholine, especially in microsomes, as compared with normal liver.
J Baraud, A Maurice
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Studies on the inhibitory effect of isavuconazole on flumatinib metabolism in vitro and in vivo
Frontiers in Pharmacology, 2023 As the validated agent for the treatment of chronic myelogenous leukemia (CML), flumatinib is a novel oral tyrosine kinase inhibitor (TKI) with higher potency and selectivity for BCR-ABL1 kinase compared to imatinib.
Ya-nan Liu +9 more
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The effect of some pesticides on lipid peroxidation and on the content of cytochrome p-450 of mitochondrial membranes and liver microsomes of pregnant rats and their embryos [PDF]
E3S Web of Conferences, 2023 The article presents data obtained in experimental studies on the effect of pesticides - butylcaptax and droppa on lipid peroxidation of mitochondrial membranes and microsomes of liver cells of pregnant rats and their embryos.
Tuychieva D. +3 more
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