Results 41 to 50 of about 2,738,308 (324)
Characterisation of androstenone metabolism in pig liver microsomes
, 2004 Androstenone (5α-androst-16-en-3-one) is a steroid pheromone produced in the testis. Excessive accumulation of androstenone together with skatole (3-methyl-indole) in the adipose tissue of some male pigs leads to "boar taint". In isolated pig hepatocytes
Doran (nee Udovikova), Olena +3 more
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Nucleotide Activation of Liver Microsomal Glucuronidation
Journal of Biological Chemistry, 1961 6 páginas en ...
Pogell, Burton M., Leloir, Luis Federico
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Journal of Pharmacy & Pharmaceutical Sciences, 2007 Purpose. The selective monoamine oxidase-B (MAO-B) inhibitor, l-deprenyl, is still used for treating Parkinson's patients, however, a disadvantage of its use lies in the formation of l-amphetamine and l-methamphetamine.
Stefania Dragoni +7 more
doaj +1 more source
Biotransformation of (−)-Verbenone by Human Liver Microsomes
Bioscience, Biotechnology, and Biochemistry, 2002 The biotransformation of (-)-verbenone was investigated with human liver microsomes by using GC-MS. Regioselective biotransformation was observed when (-)-verbenone was incubated with the liver microsomes. (-)-10-Hydroxyverbenone was formed from (-)-verbenone of kinetic analysis showed that the Km and Vmax values for the hydroxylation of (-)-verbenone ...
MIYAZAWA, Mitsuo +2 more
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Journal of Lipid Research, 1971 Rat and guinea pig liver microsomes labeled with phospholipid 32P were incubated with rat, guinea pig, and rabbit plasma in a KC1–Tris–EDTA buffer. A net transfer of microsomal phosphatidylcholine and phosphatidylethanolamine to plasma was observed.
D.B. ZILVERSMIT
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Effect of blood plasma lipoproteins on hydroxylation of benzo[a]pyrene in liver microsomes of rats
Атеросклероз, 2020 This work presents the characteristics of the catalytic activity of hydroxylation of benzo[a] pyrene (B[a]P) in rat liver microsomes using plasma lipoproteins (LP) (VLDL, LDL, HDL) as transport forms of B[a]P.
L. M. Polyakov +5 more
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Pharmaceutics, 2021 DN203368 ((E)-3-[1-(4-[4-isopropylpiperazine-1-yl]phenyl) 3-methyl-2-phenylbut-1-en-1-yl] phenol) is a 4-hydroxy tamoxifen analog that is a dual inverse agonist of estrogen-related receptor β/γ (ERRβ/γ).
Sin-Eun Kim +13 more
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Stereoselective biotransformation of ketamine in equine liver and lung microsomes
, 2008 Stereoselectivity has to be considered for pharmacodynamic and pharmacokinetic features of ketamine. Stereoselective biotransformation of ketamine was investigated in equine microsomes in vitro. Concentration curves were constructed over time, and enzyme
Theurillat, R +9 more
core +1 more source
Decavanadate displaces inositol 1,4,5-trisphosphate (IP3) from its receptor and inhibits IP3 induced Ca2+ release in permeabilized pancreatic acinar cells [PDF]
, 1991 Inositol 1,4,5-trisphosphate (IP3) induced Ca2+ release in digitonin permeabilized rat pancreatic acinar cells is specifically inhibited by decavanadate.
M. Gratzl +9 more
core +1 more source
World Journal of Traditional Chinese Medicine, 2018 Objective: Anthraquinone (AQ), a major bioactive component of the traditional Chinese medicine HeShouWu, has widespread applications in industry and medicine.
Sha Chen +6 more
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