Results 51 to 60 of about 26,828 (241)
Online Domain Adaptation for Continuous Cross-Subject Liver Viability Evaluation Based on Irregular Thermal Data [PDF]
arXiv, 2020 Accurate evaluation of liver viability during its procurement is a challenging issue and has traditionally been addressed by taking invasive biopsy on liver. Recently, people have started to investigate on the non-invasive evaluation of liver viability during its procurement using the liver surface thermal images.
arxiv
Nucleotide Activation of Liver Microsomal Glucuronidation
Journal of Biological Chemistry, 1961 6 páginas en ...
Pogell, Burton M., Leloir, Luis Federico
openaire +3 more sources
The Association of Deoxyribonucleic Acid with Liver Microsomes
Journal of Biological Chemistry, 1969 Abstract Rats and mice were given 3H-thymidine, and 18 to 24 hours later nuclei, mitochondria, and microsomes were isolated from the livers by differential centrifugation. The nucleic acids were extracted from the fractions by means of the phenol-sodium dodecyl sulfate procedure.
Schneider, W C, Kuff, E L
openaire +3 more sources
ChemMedChem, EarlyView.Heart failure involves reduced SERCA2a activity, crucial for calcium regulation in heart cells. This study reports machine learning screening of 57,423 natural products, identifying several structurally related SERCA2a activators. Three compounds enhance calcium transport in cardiac cells, despite off‐target effects, offering promising hits for ...
Carlos Cruz‐Cortés +7 more
wiley +1 more source
Inhibition of Steroidogenesis in Prostate Cancer Cells by Both a Natural and Another Synthetic Steroid. [PDF]
Drug Dev ResABSTRACT Studies suggest that vegetarians and Asians have lower mortality rates from prostate cancer compared to men who follow a Western diet. β‐sitosterol, a key compound of plant‐based diets, has been found to induce significant changes in the ultrasonic structure of the prostatic adenomas, making it a promising candidate for further prostate cancer
Cabeza M +5 more
europepmc +2 more sources
ChemMedChem, EarlyView.The review focuses on relationships of oxadiazole derivative structures and their antimycobacterial activity including target structures in mycobacteria, in vitro or in vivo pharmacokinetic parameters, and toxicity. Apart from direct antimycobacterial activity, some 1,2,4‐oxadiazole derivatives can potentiate the antimycobacterial effect of ethionamide
Marta Kučerová‐Chlupáčová
wiley +1 more source
Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles
Journal of Lipid Research, 1973 A comparative study was made on the fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in various subcellular fractions of liver and testis from rats of different ages.
Sixta Ayala +4 more
doaj
ChemMedChem, Accepted Article.The work presented herein outlines the ongoing structure‐activity relationship (SAR) studies centered around a potent, efficacious, and selective activators of the GIRK1/2 channel. Optimization studies centered around the pyrazole privileged scaffold, the N‐1‐position of the pyrazole and the right‐hand ether.
Sumaiya Nahid +8 more
wiley +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 132, Issue 2, Page 197-210, February 2023., 2023 Abstract Chronic intraperitoneal injection of thioacetamide (TAA) in rats has been used as an animal model of human cirrhosis to study the effects of the disease on drug metabolism. However, TAA inhibits P450 enzymes directly and independently of cirrhosis. We investigated the effects of chronic cirrhosis in rats, induced by 10 weeks of intraperitoneal
Devaraj Venkatapura Chandrashekar +3 more
wiley +1 more source
Journal of Lipid Research, 1984 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the rate-limiting step in cholesterol biosynthesis, exists in one active (dephosphorylated) and one inactive (phosphorylated) form in liver microsomes obtained from several ...
B Angelin +4 more
doaj