Results 61 to 70 of about 26,827 (219)
Sidedness of ceramide-phosphoethanolamine synthesis on rat liver and brain microsomal membranes.
Journal of Lipid Research, 1987 Phosphatidylethanolamine:ceramide-ethanolamine-phosphotransferase catalyzes the synthesis of ceramide-phosphoethanolamine, a sphingomyelin analogue. Its localization was studied in rat liver and brain microsomes.
M Malgat, A Maurice, J Baraud
doaj +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston +2 more
wiley +1 more source
Permeability of 16 Straight‐ and Branched‐Chain Parabens Using the Caco‐2 Assay
Journal of Applied Toxicology, EarlyView.ABSTRACT The in vitro intestinal permeability of straight‐ and branched‐chain parabens has not been extensively investigated. Sixteen parabens were tested in the Caco‐2 assay. Passive diffusion was measured using PAMPA. The transport of the MCT1 substrate, p‐coumaric acid, as well as propylparaben and isopropylparaben, was investigated.
Nicola J. Hewitt +3 more
wiley +1 more source
Journal of Lipid Research, 1998 In vitro techniques have been used to investigate the nature of microsomal cytochrome P450 involved in the metabolism of oleic acid, a physiological monounsaturated fatty acid. Like lauric acid, which is cur rently used as a model substrate of fatty acid
Fadi Adas +5 more
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Metabolic Identification Based on Proposed Mass Fragmentation Pathways of the Anabolic Steroid Bolasterone by Gas Chromatography Tandem Mass Spectrometry. [PDF]
Drug Test AnalThe metabolism of bolasterone in liver microsomes and in urine samples of rats orally treated was evaluated due to no availability of its extensive metabolism studies. Its mono‐ and di‐hydroxylated metabolites were detected by GC‐EI‐MS/MS, and the fragmentation pathways of metabolites were suggested.
Muresan AR +5 more
europepmc +2 more sources
The hydrolysis of acetylsalicylic acid by liver microsomes
Journal of Pharmacy and Pharmacology, 1968 AbstractPretreatment of rats and guinea-pigs with phenobarbitone or phenylbutazone leads to a decrease in the rate of hydrolysis of acetylsalicylic acid in vitro by liver microsomes, treatment with phenacetin does not.
J. F. Howes, W H Hunter
openaire +3 more sources
Case Report and Literature Review: Intrathyroid Thymic Carcinoma
Journal of Clinical Ultrasound, EarlyView.This case report highlights the challenges in diagnosing intrathyroid thymic carcinoma (ITTC), a rare thyroid tumor, and underscores the importance of postoperative pathology for confirmation. The study emphasizes the good prognosis of ITTC with appropriate surgical management.
Jia‐Yue Sun +3 more
wiley +1 more source
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK)
Molecules, 2019 SGC-GAK-1 (1) is a potent, selective, cell-active chemical probe for cyclin G-associated kinase (GAK). However, 1 was rapidly metabolized in mouse liver microsomes by cytochrome P450-mediated oxidation, displaying rapid clearance in liver microsomes and ...
Christopher R. M. Asquith +9 more
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Porto‐sinusoidal vascular disorder in a pediatric patient with prolidase deficiency: A case report
JPGN Reports, EarlyView.Abstract Prolidase deficiency (PD) is a rare autosomal recessive disorder affecting collagen turnover, leading to diverse clinical manifestations including dermatologic lesions, hepatosplenomegaly, and vascular anomalies. Liver involvement in PD is poorly understood, with few reported cases.
Melissa Castro +5 more
wiley +1 more source
Lipid composition and turnover of rough and smooth microsomal membranes in rat liver
Journal of Lipid Research, 1968 Subfractions of rat liver microsomes (rough, smooth I, and smooth II), isolated in a cation-containing sucrose gradient system, were analyzed. After removal of adsorbed and luminal protein, these subfractions had the same phospholipid/protein ratio ...
Hans Glaumann, Gustav Dallner
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