Results 61 to 70 of about 1,677,689 (317)
A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response [PDF]
, 2008 The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are closely related orphan nuclear hormone receptors that play a critical role as xenobiotic sensors in mammals.
Anja Rode +19 more
core +3 more sources
Über den Steringehalt pflanzlicher Mikrosomen
CHIMIA, 1975 The composition of microsomal lipids from Spirodela oligorrhiza L., Lactuca sativa L., and Allium porrum L. plants was investigated. Contamination by chloroplast lipids was calculated and eliminated, giving the lipids of “chloroplast-free microsomes ...
W. Eichenberger
doaj +1 more source
Importance relative des differentes fractions cellulaires dans la synthese hepatique des acides gras in vivo [PDF]
, 1969 The synthesis of fatty acids in mitochondria, microsomes and supernatant of mice liver was studied after administration of glucose 14C or 3H, acetate 14C or 3H and pyruvate 14C.The results suggest that the cellular structures corresponding to the ...
Favarger, P., Gerlach, J., Rous, S.
core +1 more source
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
World Journal of Traditional Chinese Medicine, 2018 Objective: Anthraquinone (AQ), a major bioactive component of the traditional Chinese medicine HeShouWu, has widespread applications in industry and medicine.
Sha Chen +6 more
doaj +1 more source
Light chain systemic amyloidosis manifested as liver failure complicated with fatal spontaneous splenic rupture: A case report [PDF]
arXiv, 2021 For a patient with manifestations of nausea, abdominal distension, spontaneous splenic rupture, obvious liver enlargement, low red blood cells and platelets, yellow sclera, and spider angioma, Congo red staining of liver and spleen tissues indicated amyloidosis.
arxiv
Molecular Pharmaceutics, 2010 The present study aims to predict the regiospecific glucuronidation of three dihydroxyflavones and seven monohydroxyflavones in human liver and intestinal microsomes using recombinant UGT isoforms. Seven monohydroxyflavones (or HFs), 2'-, 3'-, 4'-, 3-, 5-
Lan Tang +7 more
semanticscholar +1 more source
Evaluation of Liver Microsomes for Genotoxicity Sensors—Voltammetry of the Microsomes [PDF]
The Electrochemical Society Interface, 2007 The 2007 Joseph W.
James F. Rusling, Sadagopan Krishnan
openaire +2 more sources
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source
Distribution of enzymes cleaving pyridine nucleotides in animal tissues [PDF]
, 1957 A number of enzymes capable of splitting the pyridine nucleotides have been found in animal tissues. A portion of the DPNase (1) that hydrolyzes the nicotinamide ribose bond of DPN and TPN was reported in the microsomes of rat liver (1).
Jacobson, K. Bruce, Kaplan, Nathan O.
core +1 more source