Results 81 to 90 of about 1,677,689 (317)

Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles

open access: yesJournal of Lipid Research, 1973
A comparative study was made on the fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in various subcellular fractions of liver and testis from rats of different ages.
Sixta Ayala   +4 more
doaj  

Characterization of iodothyronine sulfatase activities in human and rat liver and placenta [PDF]

open access: yes, 2002
In conditions associated with high serum iodothyronine sulfate concentrations, e.g. during fetal development, desulfation of these conjugates may be important in the regulation of thyroid hormone homeostasis. However, little is known
Coughtrie, M.W.   +6 more
core   +2 more sources

3-hydroxy-3-methylglutaryl coenzyme A reductase in human liver microsomes: active and inactive forms and cross-reactivity with antibody against rat liver enzyme.

open access: yesJournal of Lipid Research, 1984
3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the rate-limiting step in cholesterol biosynthesis, exists in one active (dephosphorylated) and one inactive (phosphorylated) form in liver microsomes obtained from several ...
B Angelin   +4 more
doaj  

Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy

open access: yesCancer Communications, EarlyView.
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao   +12 more
wiley   +1 more source

Multi-Slice Low-Rank Tensor Decomposition Based Multi-Atlas Segmentation: Application to Automatic Pathological Liver CT Segmentation [PDF]

open access: yesarXiv, 2021
Liver segmentation from abdominal CT images is an essential step for liver cancer computer-aided diagnosis and surgical planning. However, both the accuracy and robustness of existing liver segmentation methods cannot meet the requirements of clinical applications.
arxiv  

Preclinical metabolism and metabolic drug-drug interaction profile of pedunculoside and rotundic acid. [PDF]

open access: yesClin Transl Sci
Pedunculoside and rotundic acid, the most abundant components in plants of the genus Ilex L. (Aquifoliaceae), exhibit biological and pharmacological significance in the treatment of cardiovascular diseases.
Wu L   +8 more
europepmc   +2 more sources

Scientific Opinion on Flavouring Group Evaluation 302 (FGE.302): N-(2-methylcyclohexyl)-2,3,4,5,6-pentafluoro-benzamide from Chemical Group 30 [PDF]

open access: yes, 2017
Publisher ...
Anastassiadou, Maria   +24 more
core   +2 more sources

Anxiolytic Effects of Indole Alkaloids From Rauvolfia ligustrina in Adult Zebrafish: Involvement of the GABAergic and 5‐HT Systems

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Benzodiazepines are widely used in the treatment of anxiety, but their use may be interrupted due to side effects. This study evaluated the indole alkaloids isocarapanaubine (indole alkaloid 1 [AIN1]) and 18‐β‐hydroxy‐3‐epi‐α‐yohimbine (indole alkaloid 2 [AIN2]), extracted from Rauvolfia ligustrina, in adult zebrafish.
Nádia Aguiar Portela Pinheiro   +10 more
wiley   +1 more source

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

open access: yesJournal of Cell Biology, 1974
The series introduced by this paper reports the results of a detailed analysis of the microsomal fraction from rat liver by density gradient centrifugation.
H. Beaufay   +6 more
semanticscholar   +1 more source

Flavonoid Profile, Biological Potentials, and In Silico Approaches of Methanol Extracts on AChE: Amaranthus retroflexus L.

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the flavonoid compounds and their biological activities in methanol extracts obtained from root, stem, leaf, and flower parts of Amaranthus retroflexus L. Flavonoids in the extracts were characterized for the first time by liquid chromatography–highresolution mass spectrometry (LC–HRMS), and a total of eight flavonoid ...
Bedrettin Selvi   +6 more
wiley   +1 more source

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