Results 91 to 100 of about 97,218 (302)

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston   +2 more
wiley   +1 more source

Proteomic Profiling of the Microsomal Root Fraction: Discrimination of Pisum sativum L. Cultivars and Identification of Putative Root Growth Markers

open access: yesProteomes, 2017
Legumes are a large and economically important family, containing a variety of crop plants. Alongside different cereals, some fruits, and tropical roots, a number of leguminosae evolved for millennia as crops with human society.
Claudia-Nicole Meisrimler   +2 more
doaj   +1 more source

Aryl Phosphoramidates of 5-Phospho Erythronohydroxamic Acid, A New Class of Potent Trypanocidal Compounds [PDF]

open access: yes, 2010
RNAi and enzymatic studies have shown the importance of 6-phosphogluconate dehydrogenase (6-PGDH) in Trypanosoma brucei for the parasite survival and make it an attractive drug target for the development of new treatments against human African ...
Alibu, Vincent P.   +6 more
core   +4 more sources

Microsomal epoxide hydrolase polymorphisms

open access: yesMolecular Medicine Reports, 2010
Microsomal epoxide hydrolase plays a dual role in the activation and detoxification of carcinogenic compounds. Two polymorphic sites have been described in exons 3 and 4 of the microsomal epoxide hydrolase gene that change tyrosine residue 113 to histidine (Tyr113His) and histidine 139 to arginine (His139Arg), respectively.
Pinarbasi, Hatice   +2 more
openaire   +6 more sources

Permeability of 16 Straight‐ and Branched‐Chain Parabens Using the Caco‐2 Assay

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The in vitro intestinal permeability of straight‐ and branched‐chain parabens has not been extensively investigated. Sixteen parabens were tested in the Caco‐2 assay. Passive diffusion was measured using PAMPA. The transport of the MCT1 substrate, p‐coumaric acid, as well as propylparaben and isopropylparaben, was investigated.
Nicola J. Hewitt   +3 more
wiley   +1 more source

Export of honeybee prepromelittin in Escherichia coli depends on the membrane potential but does not depend on proteins secA and secY [PDF]

open access: yes, 1989
Honeybee prepromelittin (70 amino acid residues), the precursor of an eukaryotic secretory protein, and a hybrid protein between prepromelittin and mouse dihydrofolate reductase (257 amino acid residues) were expressed in Escherichia coli and ...
Cobet, Werner W. E.   +3 more
core  

Microsomes are the in vitro ER

open access: yesThe Journal of Cell Biology, 2005
![Graphic][1] Microsomes (here) and ER look similar, and both have ribosomes (see dots near “ob2”). PALADEThe abundance of electron microscope (EM) images in the 1940s and 1950s brought a new problem: nomenclature. What to call all those black smudges?
openaire   +3 more sources

Case Report and Literature Review: Intrathyroid Thymic Carcinoma

open access: yesJournal of Clinical Ultrasound, EarlyView.
This case report highlights the challenges in diagnosing intrathyroid thymic carcinoma (ITTC), a rare thyroid tumor, and underscores the importance of postoperative pathology for confirmation. The study emphasizes the good prognosis of ITTC with appropriate surgical management.
Jia‐Yue Sun   +3 more
wiley   +1 more source

Ribonucleoparticle-independent transport of proteins into mammalian microsomes [PDF]

open access: yes, 1990
There are at least two different mechanisms for the transport of secretory proteins into the mammalian endoplasmic reticulum. Both mechanisms depend on the presence of a signal peptide on the respective precursor protein and involve a signal peptide ...
Cobet, Werner W. E.   +8 more
core   +2 more sources

Porto‐sinusoidal vascular disorder in a pediatric patient with prolidase deficiency: A case report

open access: yesJPGN Reports, EarlyView.
Abstract Prolidase deficiency (PD) is a rare autosomal recessive disorder affecting collagen turnover, leading to diverse clinical manifestations including dermatologic lesions, hepatosplenomegaly, and vascular anomalies. Liver involvement in PD is poorly understood, with few reported cases.
Melissa Castro   +5 more
wiley   +1 more source

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