ABSTRACT Poikiloderma with tendon contracture, myopathy and pulmonary fibrosis (POIKTMP) is a rare hereditary disorder caused by mutations in the FAM111B gene, characterised by multi‐organ fibrosis, particularly affecting the lungs. This study investigates the molecular mechanisms of fibrosis in POIKTMP through genotyping and gene expression profiling ...
Nadine Tambwe +4 more
wiley +1 more source
Comprehensive <i>in vivo</i> and <i>in vitro</i> metabolic profiling of amphenmulin: a novel pleuromutilin derivative characterized by UHPLC-Q-TOF-MS/MS. [PDF]
Wang W +5 more
europepmc +1 more source
Some Physicochemical Properties of Ribonucleoprotein from Rat Liver Microsomes
Mary G. Hamilton +2 more
openalex +1 more source
Effect of carbon monoxide and phenobarbital on hydroxylation of bile acids by rat liver microsomes [PDF]
Kurt Einarsson, Gun Johansson
openalex +1 more source
The Roles and Clinical Significance of Major Hepatic‐Derived Metabolites in Hepatocellular Carcinoma
ABSTRACT Hepatocellular carcinoma (HCC) is increasingly recognized as a metabolically orchestrated malignancy, in which hepatic‐derived metabolites function not only as byproducts of liver physiology but also as active modulators of tumor biology.
Rui Sun +5 more
wiley +1 more source
<i>In vitro</i> assessment of the impact of 30 CYP2C19 variants on citalopram metabolism. [PDF]
Wang P, Hu XX, Li JW.
europepmc +1 more source
THE SOLUBILIZATION OF MICROSOMAL ANTIBODY ACTIVITY BY THE SPECIFIC INTERACTION BETWEEN THE CRYSTALLIZABLE FRACTION OF γ-GLOBULIN AND LYMPH-NODE MICROSOMES [PDF]
Milton Kern +2 more
openalex +1 more source
Unveiling the catalytical roles of three glycosyltransferases in triterpenoid saponins in quinoa
Summary Saponins constitute a class of characteristic compounds within quinoa grains. In this study, metabolomic analysis identified 20 triterpene saponins, the majority of which were exclusively localized within the pericarp. Furthermore, three crucial glycosyltransferases were identified in quinoa.
Yiming Zhang +14 more
wiley +1 more source
Rough microsomes isolated from snap-frozen canine pancreatic tissue retain their co-translational translocation functionality. [PDF]
Croonenborghs M +4 more
europepmc +1 more source

