Results 191 to 200 of about 129,619 (377)

An adamantane‐based ligand as a novel chemical tool for thermosensory TRPM8 channel therapeutic modulation

The FEBS Journal, EarlyView.
Transient receptor potential cation channel subfamily M member 8 (TRPM8) is a cationic thermosensory channel crucial for cold sensation and menthol response. TRPM8 dysfunction leads to sensory symptoms such as cold allodynia. Targeting TRPM8 is important for treating diseases like peripheral neuropathies and cancer.
Angela Lamberti, Silvio Aprile, David Cabañero, Fabio Travagin, Laura Butron, Gregorio Fernández‐Ballester, Gian Cesare Tron, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel, Ubaldina Galli   +9 more
wiley   +1 more source

Impact of Species and Tissue Differences on In Vitro Glucuronidation of Diclofenac. [PDF]

Molecules
Asare E, Emmanuel S, Du T, Xie H, Liang D, Gao S.   +5 more
europepmc   +1 more source

Isolation of Glycopeptides from Rat Liver Microsomes Involved in the Biosynthesis of Plasma Glycoprotein

, 1968
Yu‐Teh Li, Su‐Chen Li, M. R. Shetlar
openalex   +1 more source

Polyribonucleotide synthesis by subfractions of microsomes from rat liver [PDF]

, 1968
Neil Wilkie, R.M.S. Smellie
openalex   +1 more source

Plant viruses convergently target NPR1 with various strategies to suppress salicylic acid‐mediated antiviral immunity

Journal of Integrative Plant Biology, EarlyView.
Viral infection triggers monomerization and nuclear translocation of the salicylic acid receptor NONEXPRESSOR OF PATHOGENESIS‐RELATED GENES1 (NPR1) to activate pathogenesis‐related gene expression. Nevertheless, viruses have developed one or more proteins to target NPR1 and impair its functionality through mechanisms such as inducing its degradation ...
Xue Jiang, Yingshuai Yang, Yong Li, Yongzhi Wang, Bernardo Rodamilans, Weiqin Ji, Xiaoxia Wu, Juan Antonio García, Xiaoyun Wu, Xiaofei Cheng   +9 more
wiley   +1 more source

Consecutive Steps of Nucleoside Triphosphate Hydrolysis Are Driving Transport of Precursor Proteins into the Endoplasmic Reticulum [PDF]

, 1992
Klappa, Peter, Lill, Roland, Müller, Günter, Neupert, Walter, Schlenstedt, Gabriel, Wiech, Hans, Zimmermann, Richard   +6 more
core   +1 more source

7α-Hydroxylation of cholestanol by rat liver microsomes

, 1968
Sarah Shefer, Susan Hauser, Erwin H. Mosbach   +2 more
openalex   +1 more source

Comparison of Micro‐CT and Morphometric Outcomes in a Modified Experimental Rat Model of Periodontitis

Journal of Periodontal Research, EarlyView.
Experimental periodontitis model was induced with oral gavages with Porphyromonas gingivalis and Fusobacterium nucleatum over 4 (P + 4 w), 8 (P + 8 w) and 12 (P + 12 w) weeks. Bone levels were measured with micro‐CT (linear and volumetric variables) and microscope (linear morphometric measurements) at the mandible first molar. Clinical variables—plaque
Jaime Bueno, María Martínez, Nagore Ambrosio, Juan del Rosal, Javier Robledo‐Montaña, Juan D. Gamonal, Leire Virto, Eduardo Montero, David Martín‐Hernández, María José Marín, David Herrera, Mariano Sanz, Borja García‐Bueno, Juan C. Leza, Håvard J. Haugen, Elena Figuero   +15 more
wiley   +1 more source

Liver microsomal protein content and activity in patients with hepatocellular carcinoma and cirrhosis: implications for the <i>in vivo</i> prediction of individual hepatic clearance. [PDF]

J Gastrointest Oncol
Zhou J, Gao N, Tian X, Fang Y, Gao J, Wen Q, Cui MZ, Zhang YF, Li SF, Jia LJ, Qiao HL.   +10 more
europepmc   +1 more source

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, EarlyView.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source