Results 31 to 40 of about 98,869 (304)

A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response [PDF]

, 2008
The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are closely related orphan nuclear hormone receptors that play a critical role as xenobiotic sensors in mammals.
Anja Rode, Baes, Bauer, Branko Zevnik, C. Roland Wolf, Dotzlaw, Forrester, Hustert, Jillian Ross, Kocarek, Lowry, Lukas, Meehan, Nico Scheer, Nicole Faust, Poland, Sandra Niehaves, Smith, Wolf, Wrighton   +19 more
core   +4 more sources

Newly Synthesized Creatine Derivatives as Potential Neuroprotective and Antioxidant Agents on In Vitro Models of Parkinson’s Disease

Life, 2023
Oxidative stress is one of the key factors responsible for many diseases–neurodegenerative (Parkinson and Alzheimer) diseases, diabetes, atherosclerosis, etc.
Ivanka Kostadinova, Magdalena Kondeva-Burdina, Lyubomir Marinov, Lubomir L. Vezenkov, Rumyana Simeonova   +4 more
doaj   +1 more source

CYP52X1, representing new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in entomopathogenic fungus Beauveria bassiana [PDF]

, 2012
Infection of insects by the entomopathogenic fungus Beauveria bassiana proceeds via attachment and penetration of the host cuticle. The outermost epicuticular layer or waxy layer of the insect represents a structure rich in lipids including abundant ...
Bernard, Grausem, Keyhani, Nemat O., Lesot, Agnes, Pedrini, Nicolás, Pinot, Franck, Widemann, Emilie, Zhang, Shizhu   +6 more
core   +2 more sources

Oxidative desaturation of eicosa-8,11-dienoic acid to eicosa-5,8,11-trienoic acid: comparison of different diets on oxidative desaturation at the 5,6 and 6,7 positions

Journal of Lipid Research, 1972
The oxidative desaturation of [1-14C]eicosa-8,11-dienoic acid to eicosa-5,8,11-trienoic acid by rat liver microsomes was studied, and the kinetic conditions appropriate to measure the specific activity of the enzyme were determined.
Juan C. Castuma, Angel Catala, Rodolfo R. Brenner   +2 more
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 302 (FGE.302): N-(2-methylcyclohexyl)-2,3,4,5,6-pentafluoro-benzamide from Chemical Group 30 [PDF]

, 2017
Publisher ...
Anastassiadou, Maria, Bolognesi, Claudia, Brimer, Leon, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Mennes, Wim, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +24 more
core   +3 more sources

Influence of dietary fatty acids on phospholipid fatty acid composition in subcellular particles of rat liver

Journal of Lipid Research, 1965
Male rats were divided into three groups and fed a fat-free diet (Group A), a diet supplemented with 7% of ethyl linolenate (Group B), and as a control, a diet supplemented with 7%, of ethyl linoleate (Group C) for 3 weeks.
A. Yamamoto, M. Isozaki, K. Hirayama, Y. Sakai   +3 more
doaj   +1 more source

NUCLEOSIDE-DIPHOSPHATASE OF CESTODE BOTHRIOCEPHALUS SCORPII (CESTODA: BOTHRIOCEPHALIDAE)

Российский паразитологический журнал, 2016
Objective of research: To study the activities and properties of nucleoside- diphosphatase (NDPase) in cestode Bothriocephalus scorpii.Materials and methods: Cestodes were homogenized with 10 vol. of extraction medium. NDPase was detected in mitochondria
E. A. Burenina
doaj   +1 more source

Import of honeybee prepromelittin into the endoplasmic reticulum [PDF]

, 1987
Honeybee prepromelittin is correctly processed and imported by dog pancreas microsomes. Insertion of prepromelittin into microsomal membranes, as assayed by signal sequence removal, does not depend on signal recognition particle (SRP) and docking protein.
Müller, Günter, Zimmermann, Richard
core   +2 more sources

The yeast P5 type ATPase, Spf1, regulates manganese transport into the endoplasmic reticulum [PDF]

, 2013
The endoplasmic reticulum (ER) is a large, multifunctional and essential organelle. Despite intense research, the function of more than a third of ER proteins remains unknown even in the well-studied model organism Saccharomyces cerevisiae.
A Chesi, A Samali, A Szkopińska, AB Bowman, AD Gitler, AH Futerman, Alaa Abdul-Sada, Anthony H. Futerman, AR Reddi, C Janke, C Onyewu, C Suzuki, C Suzuki, CB Brachmann, CC Paulusma, CD Davis, D Berchtold, D Lockshon, D Mandal, D Sorger, DJ Tipper, DK Breslow, E Losev, E Papanikou, E Sammels, E Wiederhold, EH Hettema, F Sherman, Fischl, Frances M. Platt, G Giaever, GA Castillon, GA Castillon, Giuseppe Condomitti, GK Voeltz, GR Corradi, H Yoshida, Howard Riezman, I Braakman, Isabelle Riezman, J Ko, J Meldolesi, J Shima, JA Sullivan, JK Pittman, JM De Freitas, K Araki, K Krumpe, KB Axelsen, LJ Wuestehube, LS Weingarten, LT Jensen, M Fujita, M Fujita, M Fujita, M North, M Schuldiner, M Schuldiner, Maya Schuldiner, MC Jonikas, MS Bae-Lee, Márton Megyeri, N Rimon, Nitzan Rimon, NP Mira, Oscar C. W. Chen, P Estrada de Martin, P Fagone, PJ Schultheis, PL Pedersen, RC Dickson, RC Dickson, RD Gietz, S Ichikawa, S Vashist, S-X Tan, SA Heidler, SC Dos Santos, SL Hansen, SR Cronin, SR Cronin, Stephen W. Michnick, TP Levine, U Loizides-Mangold, Ursula Loizides-Mangold, V Cerantola, V V Kushnirov, VC Culotta, W Kühlbrandt, X Tang, X Zhou, XF Liu, XL Guan, Y Chen, YD Lobsanov, Yifat Cohen   +95 more
core   +4 more sources

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source