Results 31 to 40 of about 129,619 (377)

DNA adducts in fish following an oil spill exposure [PDF]

open access: yes, 2006
On 12 December 1999, one third of the load of the Erika tanker, amounting to about 10,000 t crude oil flowed into sea waters close to the French Atlantic Coast.
A. Amat   +36 more
core   +1 more source

Oxidative metabolism of BDE-99 by human liver microsomes: predominant role of CYP2B6.

open access: yesToxicological Sciences, 2012
Hydroxylated polybrominated diphenyl ethers (PBDEs) have been found in human serum, suggesting that they are formed by in vivo oxidative metabolism of PBDEs.
C. Erratico, A. Szeitz, S. Bandiera
semanticscholar   +1 more source

Decavanadate displaces inositol 1,4,5-trisphosphate (IP3) from its receptor and inhibits IP3 induced Ca2+ release in permeabilized pancreatic acinar cells [PDF]

open access: yes, 1991
Inositol 1,4,5-trisphosphate (IP3) induced Ca2+ release in digitonin permeabilized rat pancreatic acinar cells is specifically inhibited by decavanadate.
Ammann   +30 more
core   +1 more source

Characterization of the human omega-oxidation pathway for omega-hydroxy-very-long-chain fatty acids [PDF]

open access: yes, 2008
Very-long-chain fatty acids (VLCFAs) have long been known to be degraded exclusively in peroxisomes via beta-oxidation. A defect in peroxisomal beta-oxidation results in elevated levels of VLCFAs and is associated with the most frequent inherited ...
Dacremont, Georges   +4 more
core   +2 more sources

Comparative oxidative metabolism of BDE-47 and BDE-99 by rat hepatic microsomes.

open access: yesToxicological Sciences, 2011
Polybrominated diphenyl ethers (PBDEs) are flame-retardant chemicals that have become ubiquitous environmental pollutants. 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) and 2,2',4,4',5-pentabromodiphenyl ether (BDE-99) are among the most prevalent PBDEs ...
C. Erratico, S. Moffatt, S. Bandiera
semanticscholar   +1 more source

Effects of trans n-6 fatty acids on the fatty acid profile of tissues and liver microsomal desaturation in the rat

open access: yesGrasas y Aceites, 1996
18:2Δ 9c,12t and 18:2 Δ9t,12c are present in our diet, as result of heat treatment of vegetable oils. A nutritional study was carried out in order to obtain more precise information on the conversion of these two isomers into long chain polyunsaturated ...
Olivier Berdeaux   +7 more
doaj   +1 more source

Morphine Metabolism in Human Skin Microsomes [PDF]

open access: yes, 2012
For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin.
Heilmann, S.   +2 more
core   +2 more sources

The composition of rat liver microsomes. The structural proteins of rat liver microsomes [PDF]

open access: yesBiochemical Journal, 1969
1. The structural-protein component of microsomal membranes was isolated by three separate methods. Analysis by polyacrylamide-gel electrophoresis indicated that the microsomal structural component is made up of a heterogeneous group of proteins. These proteins were further characterized by their phospholipid-binding capacity.
J. K. Pollak, K. A. Ward
openaire   +3 more sources

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1990
Thapsigargin, a tumor-promoting sesquiterpene lactone, discharges intracellular Ca2+ in rat hepatocytes, as it does in many vertebrate cell types. It appears to act intracellularly, as incubation of isolated rat liver microsomes with thapsigargin induces
O. Thastrup   +4 more
semanticscholar   +1 more source

Theophylline-7β-d-Ribofuranoside (Theonosine), a New Theophylline Metabolite Generated in Human and Animal Lung Tissue

open access: yesPharmaceutics, 2017
While assessing the ability of mammalian lung tissue to metabolize theophylline, a new metabolite was isolated and characterized. The metabolite was produced by the microsomal fraction of lungs from several species, including rat, rabbit, dog, pig, sheep
Daniel S. Sitar   +4 more
doaj   +1 more source

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