Results 71 to 80 of about 35,679 (167)

Development and Characterisation of a Starvation‐ and Exercise‐Induced Murine Model of Microvesicular Steatosis Relevant to Anorexia Nervosa

Liver International Communications, Volume 7, Issue 1, March 2026.
ABSTRACT Anorexia nervosa (AN) leads to severe dietary restriction, low body weight, and in many patients, hepatocellular steatosis. Clinically, hepatic fat in AN is usually macrovesicular, whereas microvesicular steatosis is more often associated with severe starvation and mitochondrial dysfunction.
Michiko Ishii, Kyoko Hoshikawa, Yuko Takeda, Taketo Nishina, Fumi Uchiyama, Fumiya Suzuki, Keita Maki, Tomohiro Katsumi, Hiroaki Haga, Yoshiyuki Ueno   +9 more
wiley   +1 more source

Effects of Newer Veterinary Macrolide Antimicrobials on the CYP3A-Dependent Metabolism in Cattle Liver Microsomes: Potential Metabolic Drug-Drug Interaction with Monensin. [PDF]

Animals (Basel)
Ichinose P, Munafó JP, Miró MV, Valente M, Moreno-Torrejón L, Larsen K, Lanusse C, Lifschitz A, Virkel G.   +8 more
europepmc   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

Mass Spectrometry Reviews, Volume 45, Issue 2, Page 244-259, March/April 2026.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke, Lahiru Wedasingha, Magnus Rydberg   +2 more
wiley   +1 more source

Comparative analysis of sex-based, vendor-based, and species differences in cytochrome P450 metabolism. [PDF]

Sci Rep
Kinatukara N, Xu X, Shah P.
europepmc   +1 more source

The NLRP3 Inflammasome: Mechanisms of Activation, Regulation, and Therapeutic Opportunities

MedComm, Volume 7, Issue 3, March 2026.
Diverse diseases converge on NLRP3. We depict a discovery‐to‐clinic track: high‐throughput/phenotypic screens, structure‐guided design, and modality innovation (allosteric inhibitors, interface blockers, degraders) deliver third‐generation, disease‐tailored NLRP3 control.
Chan Zou, Shilong Jiang, Hui Li, Kai Zhao, Dongshen Cao, Guoping Yang   +5 more
wiley   +1 more source

Development of an LC-MS/MS method to quantitatively analyze escitalopram and its metabolites with application in liver and placenta microsome metabolism. [PDF]

Front Pharmacol
Shen Y, Yao B, Guo Y, Yang Y, Liang C, Huang J, Zhang Y, Wang X.   +7 more
europepmc   +1 more source

Minor Contribution of UGT1A1 Inhibition to Atazanavir‐Related Bilirubin Elevation Supported by Conservative PBPK Modeling and Clinical Data

Clinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 583-586, March 2026.
Jin Dong, Pradeep Sharma, Rasha Emara, Derek Cheung, Weifeng Tang, Diansong Zhou, David W. Boulton, Mats Någård, Miki S. Park   +8 more
wiley   +1 more source

Potential Drivers of Successful Biocontrol: A Perspective on Parasitoids

New Zealand Journal of Zoology, Volume 53, Issue 1, March 2026.
Parasitoids are central to classical biological control, yet predicting their long‐term effectiveness post release remains challenging. In Aotearoa New Zealand, three Microctonus (Hymenoptera: Braconidae) species have been used against pest weevils, but key aspects of their biology remain poorly understood.
Meeran Hussain, Elahe Parvizi, Mark R. McNeill, Ang McGaughran   +3 more
wiley   +1 more source

Unraveling Cannabidiol's Bidirectional Regulation of Melatonin Pharmacokinetics via PEPT1/CYP1A2: Mechanistic Insights and Quantitative Projections. [PDF]

Pharmaceuticals (Basel)
Zheng B, Wang M, Zhang Q, Li C, Wang L, Zhang W, Liu C, Zhuang X.   +7 more
europepmc   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source