Microtubule-associated protein 1 light chain 3 interacts with and contributes to growth inhibiting effect of PML. [PDF]
PLoS ONE, 2014 Previously we reported that the expression of promyelocytic leukemia (PML)-retinoic acid receptor alpha (RARα) fusion gene, which is caused by specific translocation (15;17) in acute promyelocytic leukemia, can enhance constitutive autophagic activity in
Wei He +8 more
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Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation. [PDF]
ACS Nano, 2020 Zhu M +6 more
europepmc +2 more sources
Bioinformatics analysis of microtubule-associated protein-1 light chain 3 (MAP1LC3A) and (BECN1) genes in autophagy [PDF]
Cellular, Molecular and Biomedical Reports, 2022 Autophagy is an effective regulatory process for eliminating tumors and worn-out intracellular components. Different groups of enzymes and regulatory elements are involved in the autophagy process.
Ali Mirzaei, Farzaneh Fazeli
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Animal Nutrition, 2022 Deoxynivalenol (DON) is considered to be the most harmful mycotoxin that affects the intestinal health of animals and humans. Phenethyl isothiocyanate (PEITC) in feedstuff is an anti-nutritional factor and impairs nutrient digestion and absorption in the
Shuiping Liu +7 more
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A crosstalk between phosphorylation and ubiquitination of BNIP3 regulates mitophagy under hypoxia
Autophagy Reports, 2023 BNIP3 (BCL2/adenovirus e1B 19 kDa protein interacting protein 3) is a mitochondrial outer membrane protein that is sensitive to hypoxia and mediates mitophagy, a process important for mitochondrial quality control and to maintain energetic and redox ...
Yun-Ling He +4 more
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TFG: a novel regulator of ULK1-dependent autophagy
Molecular & Cellular Oncology, 2021 TRK-fused gene (TFG) is a protein implicated in multiple neurodegenerative diseases and oncogenesis. We have recently shown that, under starvation conditions, TFG contributes to spatial control of autophagy by facilitating Unc-51 like autophagy ...
Francesco Cecconi, Francesca Nazio
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Vitamin B6 Inhibits High Glucose-Induced Islet β Cell Apoptosis by Upregulating Autophagy
Metabolites, 2022 Vitamin B6 may alleviate diabetes by regulating insulin secretion and increasing insulin sensitivity, but its mechanism remains to be explored. In this study, vitamin B6-mediated autophagy and high glucose-induced apoptosis were tested to investigate the
Yu Zhang +4 more
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Neurobiology of Disease, 2012 Lithium, a drug used to treat bipolar disorders, has a variety of neuroprotective mechanisms including inhibition of glycogen synthase kinase-3 (GSK-3), a major tau kinase.
Kohei Shimada +12 more
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Acupuncture regulates autophagic flux to antagonize cerebral ischemic injury in rats
针刺研究, 2022 Objective To observe the effect of acupuncture on the cerebral infarct volume and expressions of Beclin1,microtubule-associated protein 1 light chain 3(LC3) and p62 proteins related to cell autophagy in rats with cerebral ischemia(CI), so as to explore ...
LIU Fu-rong +3 more
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Ischemia-Challenged human umbilical vascular endothelial cells: Proteomics data
Data in Brief, 2021 [Human umbilical vascular endothelial cells (HUVECs) underwent ischemia, ischemia/reperfusion and normal control (sham) treatment and marked as group I, IR and NC, respectively, were detected by quantitative proteomics and bioinformatics analyses ...
Yaping Ma +6 more
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