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Multifunctional Microtubule-Associated Proteins in Plants [PDF]
Frontiers in Plant Science, 2016 Microtubules (MTs) are involved in key processes in plant cells, including cell division, growth and development. MT-interacting proteins modulate MT dynamics and organization, mediating functional and structural interaction of MTs with other cell ...
Jana eKrtková +4 more
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Emerging role of microtubule-associated proteins on cancer metastasis [PDF]
Frontiers in Pharmacology, 2022 The major cause of death in cancer patients is strongly associated with metastasis. While much remains to be understood, microtubule-associated proteins (MAPs) have shed light on metastatic progression’s molecular mechanisms.
Onsurang Wattanathamsan +3 more
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Microtubules and Microtubule-Associated Proteins. [PDF]
Cold Spring Harb Perspect Biol, 2018 Microtubules act as "railways" for motor-driven intracellular transport, interact with accessory proteins to assemble into larger structures such as the mitotic spindle, and provide an organizational framework to the rest of the cell.
Goodson HV, Jonasson EM.
europepmc +6 more sources
Competition between microtubule-associated proteins directs motor transport [PDF]
Nature Communications, 2018 Motor and non-motor microtubule-associated proteins (MAPs) bind to the microtubule lattice, but it is unclear how their binding activities are coordinated and how this impacts motor transport.
Brigette Y. Monroy +5 more
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Manipulation of Host Microtubule Networks by Viral Microtubule-Associated Proteins [PDF]
Viruses, 2022 Diverse DNA and RNA viruses utilize cytoskeletal networks to efficiently enter, replicate, and exit the host cell, while evading host immune responses. It is well established that the microtubule (MT) network is commonly hijacked by viruses to traffic to
Dahee Seo, Don B. Gammon
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Microtubule-Associated Proteins: Structuring the Cytoskeleton. [PDF]
Trends in Cell Biology, 2019 Microtubule-associated proteins (MAPs) were initially discovered as proteins that bind to and stabilize microtubules. Today, an ever-growing number of MAPs reveals a more complex picture of these proteins as organizers of the microtubule cytoskeleton that have a large variety of functions.
Satish Bodakuntla +4 more
semanticscholar +5 more sources
The evolution of microtubule associated proteins – a reference proteomic perspective [PDF]
BMC Genomics, 2022 Microtubule associated proteins (MAPs), defined as proteins that bind microtubules but are not molecular motors or severing enzymes, play a key role in regulating microtubule stability in neurons.
Amy C. Gottschalk, Marco M. Hefti
doaj +2 more sources
Phosphorylation of Microtubule‐Associated Proteins [PDF]
European Journal of Biochemistry, 1976 1. Tubulin is not an adenosine-3':5'-monophosphate-dependent (cyclic-AMP-dependent) protein kinase. Both entities have been clearly separated by sucrose gradient ultracentrifugation. With a tubulin preparation obtained by the polymerization-depolymerization technique protein kinase had a sedimentation coefficient of 8.7 S whereas tubulin sedimented ...
L. Rappaport +3 more
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Structure and Functions of Microtubule Associated Proteins Tau and MAP2c: Similarities and Differences. [PDF]
Biomolecules, 2019 The stability and dynamics of cytoskeleton in brain nerve cells are regulated by microtubule associated proteins (MAPs), tau and MAP2. Both proteins are intrinsically disordered and involved in multiple molecular interactions important for normal ...
Melková K +9 more
europepmc +2 more sources
Role of Microtubules and Microtubule-Associated Proteins in HIV-1 Infection. [PDF]
J Virol, 2018 Recent studies show that human immunodeficiency virus type 1 (HIV-1) can utilize microtubules and their associated proteins to complete key postfusion steps during infection.
Dharan A, Campbell EM.
europepmc +2 more sources