Results 191 to 200 of about 175,942 (250)

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Calcium and Ca²⁺-Binding Proteins Regulate Microtubule and Cytoskeletal Dynamics During Mammalian Corticogenesis. [PDF]

Brain Sci
De la Merced-García DS, Valle-Bautista R, Hernández-García R, Díaz NF, Molina-Hernández A.   +4 more
europepmc   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Risk genes in progressive supranuclear palsy (PSP) affect integrity and function of microtubules. [PDF]

Front Aging
Donlon TA, Müller U.
europepmc   +1 more source

Meta-cancer phosphoproteomic analysis unveils association of Tau phosphosites with DNA damage response. [PDF]

Front Syst Biol
Poojari TR, Dcunha L, Mahin A, Gopalakrishnan AP, Ahmed M, Sekhar PS, Ummar S, John L, Modi PK, Soman S, Raju R, Palollathil A.   +11 more
europepmc   +1 more source

Stress-induced MAPK (SIMK)-dependent organization of microtubules in alfalfa. [PDF]

Mol Hortic
Hlaváčková K, Ovečka M, Šamajová O, Šamaj J.   +3 more
europepmc   +1 more source

Kinetochore proteins control microtubule dynamics in postmitotic neurons to regulate the formation of dendritic spines. [PDF]

Proc Natl Acad Sci U S A
Zhao G, Sharma A, Tang J, Aleman M, Liang X, Miner L, Qi J, Xiang W, Tian F, Goldberg Y, He Z, Shen K, Peris L, L Schwarz T.   +13 more
europepmc   +1 more source

Huntingtin as an Actin Organizer: Structural and Functional Insights

Cytoskeleton, EarlyView.
M. Capizzi, S. Humbert
wiley   +1 more source