Results 201 to 210 of about 175,942 (250)

Microtubules and microtubule-associated proteins

Current Opinion in Cell Biology, 1995
Microtubule research is becoming increasingly diverse, reflecting the many isoforms and modifications of tubulin and the many proteins with which microtubules interact. Recent advances are particularly visible in four areas: microtubule motor proteins (their structures, stepping modes, and forces); microtubule nucleation (the roles of centrosomes and ...
Eckhard Mandelkow, E M Mandelkow
exaly   +4 more sources

Phosphorylation of Microtubule‐Associated Proteins

European Journal of Biochemistry, 1976
1. Tubulin is not an adenosine-3':5'-monophosphate-dependent (cyclic-AMP-dependent) protein kinase. Both entities have been clearly separated by sucrose gradient ultracentrifugation. With a tubulin preparation obtained by the polymerization-depolymerization technique protein kinase had a sedimentation coefficient of 8.7 S whereas tubulin sedimented ...
L, Rappaport, J F, Leterrier, A, Virion, J, Nunez, J, Osty   +4 more
openaire   +2 more sources

Regulation of microtubule-associated proteins

2001
Microtubule-associated proteins (MAPs) function to regulate the assembly dynamics and organization of microtubule polymers. Upstream regulation of MAP activities is the major mechanism used by cells to modify and control microtubule assembly and organization.
L, Cassimeris, C, Spittle
openaire   +2 more sources

Microtubule-Associated Proteins and the Flexibility of Microtubules

Biochemistry, 1995
Experiments were conducted to learn whether the binding of microtubule-associated proteins (MAPs) to microtubules alters the flexibility of the microtubules. Flexibility was measured in vitro by two established techniques. The first employed measurement of the bending of the microtubule in a flow of buffer; the second involved repeated measurement of ...
J C, Kurz, R C, Williams
openaire   +2 more sources

Characterization of microtubule-associated proteins in teleosts

Cell Motility and the Cytoskeleton, 1999
Although microtubules are known to play an important role in many cellular processes, they have been virtually neglected in fish. In this report, microtubule-associated proteins (MAPs) in fish (teleost) were characterized using antibodies (Abs) directed against the mammalian MAPs tau, MAP1A and B, and MAP 2.
H G, Tomasiewicz, J G, Wood
openaire   +2 more sources

Non-motor microtubule-associated proteins

Current Opinion in Cell Biology, 1993
This past year, the structure and function of microtubule-associated proteins (MAPs) have been investigated in studies probing their phosphorylation, patterns of expression, and the function of the microtubule-binding domain. Cellular studies have also contributed new insights into the roles of these proteins in process outgrowth.
openaire   +2 more sources

Non-motor microtubule-associated proteins

Current Opinion in Cell Biology, 1991
Cloning of primary sequences has generated information on the structures of the non-motor microtubule-associated proteins and their relationship to one another. Questions about how classes of microtubule-associated proteins interact are starting to be addressed in vitro and, in vivo, tests of function are being pursued using a variety of cellular and ...
openaire   +2 more sources

Isolation of Microtubules and Microtubule-Associated Proteins

2016
Microtubules are essential cellular structures in plant cells. They are polymerized from tubulin dimers and are regulated by microtubule-associated proteins (MAPs). Here, we describe a protocol for purifying tubulin dimers and MAPs from plant cells.
Takahiro, Hamada, Seiji, Sonobe
openaire   +2 more sources