Results 191 to 200 of about 199,967 (323)

Prodrugs of the Archetypal Dynamin Inhibitor Bis‐T‐22

ChemMedChem, Volume 17, Issue 24, December 16, 2022., 2022
The Bis‐T series of compounds comprise some of the most potent inhibitors of dynamin GTPase activity yet reported, such as Bis‐T‐22 (2). The catechol moieties are believed to limit cell permeability, rendering these compounds largely inactive in cells.
Luke R. Odell, Mark J Robertson, Kelly A Young, Andrew B. McGeachie, Annie Quan, Phillip J. Robinson, Adam McCluskey   +6 more
wiley   +1 more source

The alpha tubulin acetyltransferase <i>atat-2</i> genetically interacts with <i>klp-4</i> in <i>C. elegans</i>. [PDF]

MicroPubl Biol
Reist CE, Webb MD, Mathews CM, Pieczynski JN.   +3 more
europepmc   +1 more source

Tannic acid-stained microtubules with 12, 13, and 15 protofilaments [PDF]

, 1975
P R Burton, RE Hinkley, G B Pierson
openalex   +1 more source

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai, Yongxia Li, Jiarui Du, Gang Shen, Meimei Fan, Zuopeng Su, Fulin Xu, Fang Yuan   +7 more
wiley   +1 more source

Molecular design principles for bipolar spindle organization by two opposing motors. [PDF]

Proc Natl Acad Sci U S A
Chew WX, Nédélec F, Surrey T.
europepmc   +1 more source

Association of mitochondria with microtubules in cultured cells.

, 1978
Michael H. Heggeness, Michael A. Simon, Sherwin J. Singer   +2 more
openalex   +1 more source

The mechanism of microtubule assembly in vitro [PDF]

, 1974
Marc W. Kirschner, Robley C. Williams
openalex   +1 more source

Recent Advances in Cancer Cell Membrane‐Based Nanoparticles and Cancer Cell‐Derived Small Extracellular Vesicles as Drug Delivery Platforms

Advanced NanoBiomed Research, EarlyView.
Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang, Jingjing Wang, Long Ngo, Li Li, Yuling Wang   +4 more
wiley   +1 more source

Treatment‐related adverse events of antibody–drug conjugates in clinical trials: A systematic review and meta‐analysis

Cancer, Volume 129, Issue 2, Page 283-295, 15 January 2023., 2023
Abstract Background Antibody–drug conjugates (ADCs) have complex molecular structures and have been tested in numerous clinical trials. Therefore, understanding the mechanisms of their toxicity when applied in medical practice is of high importance. Methods In a systematic review and meta‐analysis of data gathered from different scientific databases ...
Youwen Zhu, Kun Liu, Kailing Wang, Hong Zhu   +3 more
wiley   +1 more source

Dawning aurora: TPXL3 activates α-Aurora kinase and regulates mitotic spindle morphogenesis. [PDF]

Plant Cell
Kolli R.
europepmc   +1 more source