Results 191 to 200 of about 453,492 (382)
Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice
Advanced Science, EarlyView.This work reveals a novel extracellular nanoparticle transport and metabolic pathway. Following cellular uptake, Food‐grade lipid nanoparticles (FLNs) selectively fuse with lipid droplets (LDs) rather than lysosomes, driving LDs accumulation. This process activates autophagy through the AMPK‐mTOR‐ULK1 signaling axis, facilitating tumor progression ...
Chenglu Peng +10 more
wiley +1 more source
Microtubule dynamics: an interplay of biochemistry and mechanics
Nature reviews. Molecular cell biology, 2018 G. Brouhard, L. Rice
semanticscholar +1 more source
Advanced Science, EarlyView.ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen +17 more
wiley +1 more source
Assembly of microtubules from preformed, ring‐shaped protofilaments and 6‐s tubulin [PDF]
, 1974 Harold Erickson
openalex +1 more source
Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria
Advanced Science, EarlyView.A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent +8 more
wiley +1 more source
Individual microtubules viewed by immunofluorescence and electron microscopy in the same PtK2 cell [PDF]
, 1978 Mary Osborn, R. M. Webster, K. Weber
openalex +1 more source
Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene
Advanced Science, EarlyView.Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan +15 more
wiley +1 more source