Results 31 to 40 of about 359,607 (329)
A "MICROTUBULE" IN A BACTERIUM [PDF]
The Journal of Cell Biology, 1967 A study of the anchorage of the flagella in swarmers of Proteus mirabilis led to the incidental observation of microtubules. These microtubules were found in thin sections and in whole mount preparations of cells from which most of the content had been released by osmotic shock before staining negatively with potassium phosphotungstate (PTA).
Judith F. M. Hoeniger +2 more
openaire +3 more sources
eLife, 2019 Microtubules segregate chromosomes by attaching to macromolecular kinetochores. Only microtubule-end attached kinetochores can be pulled apart; how these end-on attachments are selectively recognised and stabilised is not known. Using the kinetochore and
Duccio Conti +5 more
doaj +1 more source
Frontiers in Endocrinology, 2023 β-arrestins, which have multiple cellular functions, were initially described as proteins that desensitize rhodopsin and other G protein-coupled receptors.
Tibor Szénási +4 more
doaj +1 more source
The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule. [PDF]
, 2011 There has been much effort in recent years aimed at understanding the molecular mechanism by which the Dam1 kinetochore complex is able to couple microtubule depolymerization to poleward movement. Both a biased diffusion and a forced walk model have been
Barnes, Georjana +7 more
core +2 more sources
eLife, 2014 Although it is a central question in biology, how cell shape controls intracellular dynamics largely remains an open question. Here, we show that the shape of Arabidopsis pavement cells creates a stress pattern that controls microtubule orientation ...
Arun Sampathkumar +8 more
doaj +1 more source
Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers
eLife, 2014 Chromosome segregation during mitosis depends upon Kinesin-5 motors, which display a conserved, bipolar homotetrameric organization consisting of two motor dimers at opposite ends of a central rod.
Jessica E Scholey +3 more
doaj +1 more source
Frontiers in Neuroscience, 2021 KIF1A is a microtubule-dependent motor protein responsible for fast anterograde transport of synaptic vesicle precursors in neurons. Pathogenic variants in KIF1A have been associated with a wide spectrum of neurological disorders.
Cinthia Aguilera +9 more
doaj +1 more source
Dynamics of Microtubule Growth and Catastrophe [PDF]
, 2007 We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii ...
Antal, T. +4 more
core +1 more source
eLife, 2017 The physiological functions of microtubules (MTs) are poorly understood in many differentiated cell types. We developed a genetic toolkit to study MT dynamics and function in diverse cells.
Andrew Muroyama, Terry Lechler
doaj +1 more source
The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability
eLife, 2020 Microtubules are cytoskeletal polymers whose function depends on their property to switch between states of growth and shrinkage. Growing microtubules are thought to be stabilized by a GTP cap at their ends.
Johanna Roostalu +5 more
doaj +1 more source