Results 51 to 60 of about 249,538 (351)

A continuous model for microtubule dynamics with catastrophe, rescue and nucleation processes

open access: yes, 2009
Microtubules are a major component of the cytoskeleton distinguished by highly dynamic behavior both in vitro and in vivo. We propose a general mathematical model that accounts for the growth, catastrophe, rescue and nucleation processes in the ...
A. Quarteroni   +6 more
core   +1 more source

Prime movers : mechanochemistry of mitotic kinesins [PDF]

open access: yes, 2014
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
A Blangy   +184 more
core   +1 more source

Immunolocalization of dually phosphorylated MAPKs in dividing root meristem cells of Vicia faba, Pisum sativum, Lupinus luteus and Lycopersicon esculentum [PDF]

open access: yes, 2015
Key message In plants, phosphorylated MAPKs display constitutive nuclear localization; however, not all studied plant species show co-localization of activated MAPKs to mitotic microtubules.
A Bessard   +42 more
core   +2 more sources

Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces

open access: yeseLife, 2018
Presence of multiple copies of the microtubule-binding NDC80 complex is an evolutionary conserved feature of kinetochores, points of attachment of chromosomes to spindle microtubules.
Vladimir A Volkov   +3 more
doaj   +1 more source

The preprophase band-associated kinesin-14 OsKCH2 is a processive minus-end-directed microtubule motor. [PDF]

open access: yes, 2018
In animals and fungi, cytoplasmic dynein is a processive minus-end-directed motor that plays dominant roles in various intracellular processes. In contrast, land plants lack cytoplasmic dynein but contain many minus-end-directed kinesin-14s.
Bowen, Joel   +7 more
core   +3 more sources

Interplay between kinesin-1 and cortical dynein during axonal outgrowth and microtubule organization in Drosophila neurons

open access: yeseLife, 2015
In this study, we investigated how microtubule motors organize microtubules in Drosophila neurons. We showed that, during the initial stages of axon outgrowth, microtubules display mixed polarity and minus-end-out microtubules push the tip of the axon ...
Urko del Castillo   +3 more
doaj   +1 more source

Ionizing Radiation Effects on Hs 578Bst Microtubules

open access: yesFrontiers in Physics, 2020
Microtubules are one of the three components of the cell cytoskeleton. They are hollow wires, with a diameter of about 25 nm, formed by 13 laterally associated protofilaments composed by dimers of α and β-tubulin.
L. Bruni   +8 more
doaj   +1 more source

Tubulins in C. elegans [PDF]

open access: yes, 2018
The C. elegans tubulin family is composed of nine α-, six β-, and one γ-tubulin. Tubulins are highly conserved, functioning as α-β heterodimers that assemble into microtubules.
Hurd, Daryl D.
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Elastic properties of grafted microtubules [PDF]

open access: yes, 2005
We use single-particle tracking to study the elastic properties of single microtubules grafted to a substrate. Thermal fluctuations of the free microtubule's end are recorded, in order to measure position distribution functions from which we calculate ...
A. Jonas   +34 more
core   +4 more sources

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