Immunomagnetic Isolation and Enrichment of Microvascular Endothelial Cells from Human Adipose Tissue
Human adipose tissue-resident microvascular endothelial cells are not only garnering attention for their emergent role in the pathogenesis of obesity-related metabolic disorders, but are also of considerable interest for vascular tissue engineering due ...
Jeremy Antonyshyn +6 more
doaj +1 more source
Mechanisms of modulation of brain microvascular endothelial cells function by thrombin. [PDF]
Brain microvascular endothelial cells are a critical component of the blood-brain barrier. They form a tight monolayer which is essential for maintaining the brain homeostasis.
Abood, Mary E. +4 more
core +2 more sources
Brain microvascular endothelial cells form the interface between nervous tissue and circulating blood, and regulate central nervous system homeostasis. Brain microvascular endothelial cells differ from peripheral endothelial cells with regards expression
Qi-jin Yu +3 more
doaj +1 more source
Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension. [PDF]
BACKGROUND: Coagulation factor VIII (FVIII) deficiency leads to haemophilia A. Conversely, elevated plasma levels are a strong predictor of recurrent venous thromboemboli and pulmonary hypertension phenotypes in which in situ thromboses are implicated ...
Angus, G +9 more
core +1 more source
Cell-surface proteins that can endocytose into brain microvascular endothelial cells serve as promising candidates for receptor-mediated transcytosis across the blood–brain barrier (BBB).
Shingo Ito +6 more
doaj +1 more source
Induction of brain microvascular endothelial cell urokinase expression by Cryptococcus neoformans facilitates blood-brain barrier invasion. [PDF]
The invasive ability of the blood-borne fungal pathogen Cryptococcus neoformans can be enhanced through interactions with host plasma components, such as plasminogen.
Jamal Stie, Deborah Fox
doaj +1 more source
Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura +8 more
core +2 more sources
Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J. +2 more
core +1 more source
Radiation-induced apoptosis in microvascular endothelial cells [PDF]
The response of the microvasculature to ionizing radiation is thought to be an important factor in the overall response of both normal tissues and tumours. It has recently been reported that basic fibroblast growth factor (bFGF), a potent mitogen for endothelial cells, protects large vessel endothelial cells from radiation-induced apoptosis in vitro ...
R E, Langley +4 more
openaire +2 more sources
DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration. [PDF]
Deleted in liver cancer 1 (DLC1) is a RhoGTPase activation protein-containing tumor suppressor that associates with various types of cancer. Although DLC2 shares a similar domain structure with that of DLC1, the function of DLC2 is not well characterized.
Chen, N-T +5 more
core +3 more sources

