Results 251 to 260 of about 203,456 (311)

Fenofibrate mitigates the dysfunction of high glucose-driven human retinal microvascular endothelial cells by suppressing NLRP3 inflammasome. [PDF]

Int J Ophthalmol
Shi Y, Chen HM, Liu AH, Li XR.
europepmc   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells. [PDF]

Redox Biol
Hidalgo M, Railef B, Rodríguez V, Navarro C, Rubio V, Meneses-Pacheco J, Soto-Alarcón S, Kreindl C, Añazco C, Zuñiga L, Porras O.   +10 more
europepmc   +1 more source

A first‐trimester mechanistic framework integrating three Physiopathologic biomarker domains for pre‐eclampsia classification

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To develop and internally validate a mechanistic, three‐domain framework for early classification and prediction of pre‐eclampsia (PE) using first‐trimester angiogenic, uteroplacental, and maternal vascular biomarkers. Methods In a prospective cohort of 1925 singleton pregnancies screened at 11 to 13.6 weeks, placental growth factor (
Johnatan Torres‐Torres, Salvador Espino‐y‐Sosa, Raigam Jafet Martinez‐Portilla, Elsa Romelia Moreno‐Verduzco, Irma Eloisa Monroy‐Muñoz, Juan Mario Solis‐Paredes, Javier Perez Duran, Hector Borboa‐Olivares, Lourdes Rojas‐Zepeda   +8 more
wiley   +1 more source

Proteome profile differences among human, monkey, and mouse brain microvessels and cultured brain microvascular endothelial cells. [PDF]

Fluids Barriers CNS
Kumabe H, Masuda T, Ito S, Furihata T, Toda A, Mogi M, Araki N, Ohtsuki S.   +7 more
europepmc   +1 more source

RIPK1 kinase drove brain microvascular endothelial cells death and blood-brain barrier disruption in neonatal Escherichia coli meningitis. [PDF]

Nat Commun
Wang X, Zhang Y, Chen X, Fu K, Cui J, Wu J, Sun Y, Ren J, Xue F, Dai J, Tang F.   +10 more
europepmc   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

High Glucose Treatment Induces Nuclei Aggregation of Microvascular Endothelial Cells via the foxo1a-klf2a Pathway. [PDF]

Arterioscler Thromb Vasc Biol
Wang X, Kang X, Li B, Chen C, Chen L, Liu D.   +5 more
europepmc   +1 more source

BK Polyomavirus Infection of Bladder Microvascular Endothelial Cells Leads to the Activation of the cGAS-STING Pathway. [PDF]

J Med Virol
Bruštíková K, Ryabchenko B, Liebl D, Horníková L, Forstová J, Huérfano S.   +5 more
europepmc   +1 more source

Inactivation of BACE2 stimulates release of endothelin-1 from human brain microvascular endothelial cells. [PDF]

J Alzheimers Dis Rep
He T, Katusic ZS.
europepmc   +1 more source