Results 21 to 30 of about 203,456 (311)

Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]

, 2019
No abstract ...
Berry, C, Ford, TJ, Hainsworth, AH, Kaski, JC, Pereira, AC, Sidik, N, Touyz, RM   +6 more
core   +2 more sources

Angiopoietins differentially influence in vitro angiogenesis by endothelial cells of different origin [PDF]

, 2011
Angiopoietins are important growth factors for vascular development and quiescence. They are promising targets for pro-or anti-angiogenic therapies in diverse pathologies, but the mechanisms of the ANGPT/TIE2 system are complex and not well understood ...
Bahramsoltani, Mahtab, Cornillie, Pieter, De Spiegelaere, Ward, Plendl, Johanna, Van Den Broeck, Wim   +4 more
core   +2 more sources

Role of Microvascular Endothelial Cells in Inflammation

Journal of Investigative Dermatology, 1993
Endothelial cells are critical elements in the evolution of all types of cutaneous inflammation. They participate through the synthesis and secretion of pro-inflammatory cytokines, including interleukin 1 (IL-1), IL-6, and IL-8, as well as M-CSF, G-CSF, GM-CSF, gro alpha, and MCP.
Swerlick, Robert A., Lawley, Thomas J.
openaire   +2 more sources

Shear Stress Rescued the Neuronal Impairment Induced by Global Cerebral Ischemia Reperfusion via Activating PECAM-1-eNOS-NO Pathway

Frontiers in Cell and Developmental Biology, 2021
Microvessel hypoperfusion following ischemic stress resulted in a decreased shear stress of brain microvascular endothelial cells (BMECs) and contributed to abnormal expression of PECAM-1 after global cerebral ischemia/reperfusion (I/R) injury.
Jing-Quan Gao, Peng Wang, Jun-Wei Yan, Li-Na Ba, Pi-Long Shi, Hong-Mei Wu, Xue-Ying Guan, Yong-gang Cao, Hong-Li Sun, Xiao-Yuan Mao, Xiao-Yuan Mao   +10 more
doaj   +1 more source

Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]

, 2015
Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco, BATTAGLIONE, Ezio, BIANCHI, ENRICA, Feher, Janos, Kovacs, Illes, MAGLIULO, Giuseppe, Micera, Alessandra, ORLANDO, Maria Patrizia, PLATEROTI, Rocco, Ripandelli, Guido, TAURONE, SAMANTA   +10 more
core   +1 more source

Upcyte^®Microvascular Endothelial Cells Repopulate Decellularized Scaffold [PDF]

Tissue Engineering Part C: Methods, 2013
A general problem in tissue engineering is the poor and insufficient blood supply to guarantee tissue cell survival as well as physiological tissue function. To address this limitation, we have developed an in vitro vascularization model in which a decellularized porcine small bowl segment, representing a capillary network within a collagen matrix ...
Scheller, Katharina, Dally, Iris, Hartmann, Nadja, Münst, Bernhard, Braspenning, Joris, Walles, Heike   +5 more
openaire   +2 more sources

Robo4 inhibits gamma radiation-induced permeability of a murine microvascular endothelial cell by regulating the junctions

Cellular & Molecular Biology Letters, 2023
Background Hematopoietic stem cell transplantation involves irradiation preconditioning which causes bone marrow endothelial cell dysfunction. While much emphasis is on the reconstitution of hematopoietic stem cells in the bone marrow microenvironment ...
Seyram Yao Adzraku, Guozhang Wang, Can Cao, Yurong Bao, Yizhou Wang, Alhaji Osman Smith, Yuwei Du, Haiyang Wang, Yue Li, Kailin Xu, Jianlin Qiao, Wen Ju, Lingyu Zeng   +12 more
doaj   +1 more source

Angiogenesis in tissue engineering : Breathing life into constructed tissue substitutes [PDF]

, 2006
Long-term function of three-dimensional (3D) tissue constructs depends on adequate vascularization after implantation. Accordingly, research in tissue engineering has focused on the analysis of angiogenesis.
Amon, Michaela, Carvalho, Carlos, Farhadi, Jian, Germann, Gunter, Haeufel, Joerg M., Harder, Yves, Heberer, Michael, Junker, Dominic, Laschke, Matthias W., Martin, Ivan, Menger, Michael D., Ring, Andrej, Ruecker, Martin, Schramm, Rene, Torio-Padron, Nestor, Vollmar, Brigitte   +15 more
core   +1 more source

Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells [PDF]

Journal of Biological Chemistry, 2018
Atypical hemolytic uremic syndrome (aHUS) and bone marrow transplantation-associated thrombotic microangiopathy (TA-TMA) are associated with excessive activation of the alternative complement pathway (AP) and with severe renal, but rarely cerebral, microvascular damage.
Sarah E, Sartain, Nancy A, Turner, Joel L, Moake   +2 more
openaire   +2 more sources

Plasmodium falciparum Parasite Lines Expressing DC8 and Group A PfEMP1 Bind to Brain, Intestinal, and Kidney Endothelial Cells

Frontiers in Cellular and Infection Microbiology, 2022
Cytoadhesion of Plasmodium falciparum-infected red blood cells is a virulence determinant associated with microvascular obstruction and organ complications.
Luana S. Ortolan, Marion Avril, Jun Xue, Karl B. Seydel, Karl B. Seydel, Ying Zheng, Joseph D. Smith, Joseph D. Smith   +7 more
doaj   +1 more source