Results 31 to 40 of about 15,195 (308)

Microvesicles and Microvesicle-Associated microRNAs Reflect Glioblastoma Regression: Microvesicle-Associated miR-625-5p Has Biomarker Potential

International Journal of Molecular Sciences, 2022
Glioblastoma (GB) is the most aggressive and recurrent form of brain cancer in adults. We hypothesized that the identification of biomarkers such as certain microRNAs (miRNAs) and the circulating microvesicles (MVs) that transport them could be key to establishing GB progression, recurrence and therapeutic response.
Natalia Simionescu, Miruna Nemecz, Anca-Roxana Petrovici, Ioan Sebastian Nechifor, Razvan-Cristian Buga, Marius Gabriel Dabija, Lucian Eva, Adriana Georgescu   +7 more
openaire   +2 more sources

Rapid isolation and quantification of extracellular vesicles from suspension‐adapted human embryonic kidney cells using capillary‐channeled polymer fiber spin‐down tips

ELECTROPHORESIS, Volume 44, Issue 1-2, Page 190-202, January 2023., 2023
Abstract Exosomes, a subset of extracellular vesicles (EVs, 30–200‐nm diameter), serve as biomolecular snapshots of their cell of origin and vehicles for intercellular communication, playing roles in biological processes, including homeostasis maintenance and immune modulation.
Kaylan K. Jackson, R. Kenneth Marcus
wiley   +1 more source

Comparison of Four Purification Methods on Serum Extracellular Vesicle Recovery, Size Distribution, and Proteomics

Proteomes, 2023
In recent decades, the role played by extracellular vesicles in physiological and pathological processes has attracted attention. Extracellular vesicles are released by different types of cells and carry molecules that could become biomarkers for the ...
Dianny Elizabeth Jimenez, Muhammad Tahir, Muhammad Faheem, Wellington Bruno dos Santos Alves, Barbara de Lucena Correa, Gabriel Rocha de Andrade, Martin R. Larsen, Getulio Pereira de Oliveira, Rinaldo Wellerson Pereira   +8 more
doaj   +1 more source

Biology and biogenesis of shed microvesicles [PDF]

Small GTPases, 2016
The ability of cells to transmit bioactive molecules to recipient cells and the extracellular environment is a fundamental requirement for both normal physiology and disease pathogenesis. It has traditionally been thought that soluble factors released from cells were responsible for this cellular signaling but recent research has revealed a fundamental
Crislyn D'Souza-Schorey, Christopher J. Tricarico, James W. Clancy   +2 more
openaire   +3 more sources

Correction: O2-3-Aminopropyl diazeniumdiolates suppress the progression of highly metastatic triple-negative breast cancer by inhibition of microvesicle formation via nitric oxide-based epigenetic regulation

Chemical Science, 2020
Correction for ‘O2-3-Aminopropyl diazeniumdiolates suppress the progression of highly metastatic triple-negative breast cancer by inhibition of microvesicle formation via nitric oxide-based epigenetic regulation’ by Fenghua Kang et al., Chem. Sci., 2018,
Fenghua Kang, Jiayi Zhu, Jianbing Wu, Tian Lv, H. Xiang, Jide Tian, Yihua Zhang, Zhangjian Huang   +7 more
semanticscholar   +1 more source

A potential role of microvesicle-containing miR-223/142 in lung inflammation

Thorax, 2019
Background Uncontrolled lung inflammation is one of the prominent features in the pathogenesis of lung infection- associated acute lung injury (ALI).
Duo Zhang, Heedoo Lee, Xiaoyun Wang, Michael Groot, L. Sharma, C. D. Dela Cruz, Yang Jin   +6 more
semanticscholar   +1 more source

Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia

Scientific Reports, 2020
Preeclampsia is the most common placental pathology in pregnant females, with increased morbidity and mortality incurred on the mother and the fetus. There is a need for improved biomarkers for diagnosis and monitoring of this condition.
L. Levine, Andreas Habertheuer, Chirag Ram, L. Korutla, N. Schwartz, Robert Hu, Sanjana Reddy, A. Freas, P. Zielinski, Joey Harmon, S. Molugu, S. Parry, P. Vallabhajosyula   +12 more
semanticscholar   +1 more source

Microvesicles Correlated with Components of Metabolic Syndrome in Men with Type 2 Diabetes Mellitus and Lowered Testosterone Levels But Were Unaltered by Testosterone Therapy

Journal of Diabetes Research, 2017
Aims. To investigate how circulating microvesicle phenotypes correlate with insulin sensitivity, body composition, plasma lipids, and hepatic fat accumulation.
Jaco Botha, Line Velling Magnussen, Morten Hjuler Nielsen, Tine Bo Nielsen, Kurt Højlund, Marianne Skovsager Andersen, Aase Handberg   +6 more
doaj   +1 more source

Microvesicles as Mediators of Tissue Regeneration [PDF]

Translational Research, 2014
The use of stem cells in the treatment of various diseases and injuries has received increasing interest during the past decade. Injected stem cells, such as mesenchymal stem cells, stimulate tissue repair largely through the secretion of soluble factors that regulate various processes of tissue regeneration, including inflammatory responses, apoptosis,
Nobuaki Kikyo, Keith Sabin
openaire   +3 more sources

Urinary Microvesicle-Bound Uromodulin: A Potential Molecular Biomarker in Diabetic Kidney Disease

Journal of Diabetes Research, 2017
This study was designed to investigate the changes of urinary microvesicle-bound uromodulin and total urinary uromodulin levels in human urine and the correlations with the severity of diabetic kidney disease (DKD).
Neng-jun Lou, Yi-hong Ni, Hong-ying Jia, Jing-ti Deng, Lu Jiang, Feng-jie Zheng, Ai-li Sun   +6 more
doaj   +1 more source