Results 31 to 40 of about 18,155 (253)

Lymphatic and Blood Endothelial Extracellular Vesicles: A Story Yet to Be Written

open access: yesLife, 2022
Extracellular vesicles (EVs), such as exosomes, microvesicles, and apoptotic bodies, are cell-derived, lipid bilayer-enclosed particles mediating intercellular communication and are therefore vital for transmitting a plethora of biological signals.
Johanna Trisko   +4 more
doaj   +1 more source

Circulating Extracellular Vesicles and Endothelial Damage in Sickle Cell Disease

open access: yesFrontiers in Physiology, 2020
Endothelial damage is central to the pathogenesis of many of the complications of sickle cell disease. Circulating extracellular vesicles (EVs) have been implicated in modulating endothelial behavior in a variety of different, diseases with vascular ...
Gabrielle Lapping-Carr   +3 more
doaj   +1 more source

Syncytiotrophoblast extracellular microvesicle profiles in maternal circulation for noninvasive diagnosis of preeclampsia

open access: yesScientific Reports, 2020
Preeclampsia is the most common placental pathology in pregnant females, with increased morbidity and mortality incurred on the mother and the fetus. There is a need for improved biomarkers for diagnosis and monitoring of this condition.
L. Levine   +12 more
semanticscholar   +1 more source

Urinary Microvesicle-Bound Uromodulin: A Potential Molecular Biomarker in Diabetic Kidney Disease

open access: yesJournal of Diabetes Research, 2017
This study was designed to investigate the changes of urinary microvesicle-bound uromodulin and total urinary uromodulin levels in human urine and the correlations with the severity of diabetic kidney disease (DKD).
Neng-jun Lou   +6 more
doaj   +1 more source

Effect of storage on physical and functional properties of extracellular vesicles derived from neutrophilic granulocytes [PDF]

open access: yesJournal of Extracellular Vesicles, 2014
Aim: To carry out a systematic study on the effect of different storage conditions on the number as well as the physical and functional properties of antibacterial extracellular vesicles (EVs) derived from human neutrophilic granulocytes.
Ákos M. Lőrincz   +6 more
doaj   +1 more source

A potential role of microvesicle-containing miR-223/142 in lung inflammation

open access: yesThorax, 2019
Background Uncontrolled lung inflammation is one of the prominent features in the pathogenesis of lung infection- associated acute lung injury (ALI).
Duo Zhang   +6 more
semanticscholar   +1 more source

CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections

open access: yesFrontiers in Immunology, 2019
The protective roles of endosomal toll-like receptors (TLRs) and cytosolic nucleic acid sensors are well elucidated, but the pathogenic host factors during viral infections remain unclear. Spleen tyrosine kinase (Syk)-coupled C-type lectins (CLECs) CLEC2
Pei-Shan Sung   +4 more
doaj   +1 more source

Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis

open access: yesTheranostics, 2019
Although glucocorticoids are the mainstays in the treatment of renal diseases for decades, the dose dependent side effects have largely restricted their clinical use.
T. Tang   +14 more
semanticscholar   +1 more source

Extracellular Vesicles and Their Convergence with Viral Pathways

open access: yesAdvances in Virology, 2012
Extracellular vesicles (microvesicles), such as exosomes and shed microvesicles, contain a variety of molecules including proteins, lipids, and nucleic acids.
Thomas Wurdinger   +5 more
doaj   +1 more source

Circulating Thrombomodulin: Release Mechanisms, Measurements, and Levels in Diseases and Medical Procedures

open access: yesTH Open, 2022
Thrombomodulin (TM) is a type-I transmembrane protein that is mainly expressed on endothelial cells and plays important roles in many biological processes. Circulating TM of different forms are also present in biofluids, such as blood and urine.
Mallorie Boron   +3 more
doaj   +1 more source

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