Results 41 to 50 of about 15,493 (301)

Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer

open access: yesFrontiers in Pharmacology, 2018
Exosomes and microvesicles (EMV) are lipid bilayer-enclosed structures, released by cells and involved in intercellular communication through transfer of proteins and genetic material.
Uchini S. Kosgodage   +8 more
semanticscholar   +1 more source

Characterizing Extracellular Vesicles and Their Diverse RNA Contents

open access: yesFrontiers in Genetics, 2020
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular communication agents that regulate physiological states by transporting
Eren M. Veziroglu   +3 more
doaj   +1 more source

Tumoral microvesicle–activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma

open access: yesThe FASEB Journal, 2019
Metabolic reprogramming is a hallmark of cancer. Stromal cells could function as providers of energy metabolites for tumor cells by undergoing the “reverse Warburg effect,” but the mechanism has not been fully elucidated.
E. Jiang   +12 more
semanticscholar   +1 more source

Natural IgM antibodies inhibit microvesicle-driven coagulation and thrombosis.

open access: yesBlood, 2020
Thrombosis and the complications associated with it are a major cause of morbidity and mortality worldwide. Microvesicles (MVs), a class of extracellular vesicles, are increasingly recognized as mediators of coagulation and biomarkers of thrombotic risk.
G. Obermayer   +12 more
semanticscholar   +1 more source

Red Blood Cell Homeostasis: Mechanisms and Effects of Microvesicle Generation in Health and Disease

open access: yesFrontiers in Physiology, 2018
Red blood cells (RBCs) generate microvesicles to remove damaged cell constituents such as oxidized hemoglobin and damaged membrane constituents, and thereby prolong their lifespan.
J. K. F. Leal   +2 more
semanticscholar   +1 more source

Membrane Microvesicles as Potential Vaccine Candidates [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The prevention and control of infectious diseases is crucial to the maintenance and protection of social and public healthcare. The global impact of SARS-CoV-2 has demonstrated how outbreaks of emerging and re-emerging infections can lead to pandemics of significant public health and socio-economic burden.
Toshana L. Foster   +6 more
openaire   +3 more sources

Microvesicle-Mediated Delivery of Minicircle DNA Results in Effective Gene-Directed Enzyme Prodrug Cancer Therapy

open access: yesMolecular Cancer Therapeutics, 2019
An emerging approach for cancer treatment employs the use of extracellular vesicles, specifically exosomes and microvesicles, as delivery vehicles. We previously demonstrated that microvesicles can functionally deliver plasmid DNA to cells and showed ...
M. Kanada   +15 more
semanticscholar   +1 more source

Microvesicles as major biomarkers? [PDF]

open access: yesNature Reviews Cancer, 2012
A sensitive method to detect and monitor glioblastomas through the analysis of microvesicles in the blood is reported inNature Medicine.
openaire   +2 more sources

Circulating Microvesicles in Regenerative Angiogenesis [PDF]

open access: yesCurrent Trends in Biomedical Engineering & Biosciences, 2017
Extracellular microvesicles (EVs) released by different cells have been shown to facilitate the transfer of several pro-angiogenic as well as anti-antigenic factors that can regulate gene expression in endothelial cells. Our recent study has demonstrated that the profiles of cytokines and angiogenic-active factors in EVs are significantly changed in ...
Drożdż, Anna, Stępień, Ewa
openaire   +3 more sources

The role of exosomes in peripheral nerve regeneration

open access: yesNeural Regeneration Research, 2015
Peripheral nerve injuries remain problematic to treat, with poor functional recovery commonly observed. Injuries resulting in a nerve gap create specific difficulties for axonal regeneration.
Rosanna C Ching, Paul J Kingham
doaj   +1 more source

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