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Membrane Microvesicles as Potential Vaccine Candidates [PDF]
International Journal of Molecular Sciences, 2021 The prevention and control of infectious diseases is crucial to the maintenance and protection of social and public healthcare. The global impact of SARS-CoV-2 has demonstrated how outbreaks of emerging and re-emerging infections can lead to pandemics of significant public health and socio-economic burden.
Layaly Shkair +5 more
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Sorting Mechanisms for MicroRNAs into Extracellular Vesicles and Their Associated Diseases
Cells, 2020 Extracellular vesicles (EV) are secretory membranous elements used by cells to transport proteins, lipids, mRNAs, and microRNAs (miRNAs). While their existence has been known for many years, only recently has research begun to identify their function in ...
Michael Groot, Heedoo Lee
doaj +1 more source
Neural Regeneration Research, 2015 MicroRNA-124 contributes to neurogenesis through regulating its targets, but its expression both in the brain of Huntington′s disease mouse models and patients is decreased.
Tian Liu +3 more
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Journal of Extracellular Vesicles, 2022 The development of a new large‐scale purification protocol is required for research on the reliable bioactivity and drug discovery of extracellular vesicles (EVs).
Naohiro Seo +9 more
doaj +1 more source
Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets [PDF]
, 2019 © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Antwi-Baffour, Samuel +5 more
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Frontiers in Endocrinology, 2017 Tumors evolve in complex and dynamic microenvironments that they rely on for sustained growth, invasion, and metastasis. Within this space, tumor cells and non-malignant cells are in frequent communication.
Ryan Sullivan +10 more
doaj +1 more source
Immunoregulatory Effects of Stem Cell-Derived Extracellular Vesicles on Immune Cells
Frontiers in Immunology, 2020 Recent investigations on the regulatory action of extracellular vesicles (EVs) on immune cells in vitro and in vivo have sparked interest on the subject.
Min Xie +6 more
doaj +1 more source
Membrane Ballooning in Aggregated Platelets is Synchronised and Mediates a Surge in Microvesiculation:Synchronised ballooning and microvesiculation [PDF]
, 2017 Human platelet transformation into balloons is part of the haemostatic response and thrombus architecture. Here we reveal that in aggregates of platelets in plasma, ballooning in multiple platelets occurs in a synchronised manner.
Agbani, Ejaife +3 more
core +2 more sources
Thromboinflammatory effects of RBC microvesicles [PDF]
Blood, 2020 In this issue of Blood, Noubouossie et al provide new insights into potential mechanisms for thromboinflammatory complications associated with red blood cell (RBC) transfusions. By using leukoreduced RBC units to isolate RBC microvesicles (RBC-MVs), they document that RBC-MVs activate factor IX (FIX) via 2 distinct pathways: (1) the canonical ...
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Microvesicles and Cancer Associated Thrombosis [PDF]
Seminars in Thrombosis and Hemostasis, 2019 AbstractMicrovesicles (MVs) are small membrane enclosed structures released into the extracellular space by virtually all cell types. Their composition varies according to the cell origin and the stimulus which caused their formation. They harbor functional molecules and participate in intercellular communication.
Lacroix, Romaric +8 more
openaire +4 more sources