Results 41 to 50 of about 15,195 (308)

Extracellular Vesicles and Their Convergence with Viral Pathways

Advances in Virology, 2012
Extracellular vesicles (microvesicles), such as exosomes and shed microvesicles, contain a variety of molecules including proteins, lipids, and nucleic acids.
Thomas Wurdinger, NaTosha N. Gatson, Leonora Balaj, Balveen Kaur, Xandra O. Breakefield, D. Michiel Pegtel   +5 more
doaj   +1 more source

Isolation and characterization of platelet-derived extracellular vesicles

Journal of Extracellular Vesicles, 2014
Background: Platelet-derived extracellular vesicles (EVs) participate, for example, in haemostasis, immunity and development. Most studies of platelet EVs have targeted microparticles, whereas exosomes and EV characterization under various conditions ...
Maria T. Aatonen, Tiina Öhman, Tuula A. Nyman, Saara Laitinen, Mikaela Grönholm, Pia R.-M. Siljander   +5 more
doaj   +1 more source

Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer

Frontiers in Pharmacology, 2018
Exosomes and microvesicles (EMV) are lipid bilayer-enclosed structures, released by cells and involved in intercellular communication through transfer of proteins and genetic material.
Uchini S. Kosgodage, R. Mould, A. Henley, A. Nunn, G. Guy, Elizabeth Louise Thomas, J. Inal, Jimmy D Bell, S. Lange   +8 more
semanticscholar   +1 more source

Microvesicles: ROS scavengers and ROS producers [PDF]

Journal of Extracellular Vesicles, 2019
ABSTRACTThis review analyzes the relationship between microvesicles and reactive oxygen species (ROS). This relationship is bidirectional; on the one hand, the number and content of microvesicles produced by the cells are affected by oxidative stress conditions; on the other hand, microvesicles can directly and/or indirectly modify the ROS content in ...
Bodega Magro, Guillermo, Alique Aguilar, Matilde, Puebla Jiménez, Lilian, Carracedo, Julia, Ramírez Chamond, Manuel Rafael   +4 more
openaire   +6 more sources

Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis

Theranostics, 2019
Although glucocorticoids are the mainstays in the treatment of renal diseases for decades, the dose dependent side effects have largely restricted their clinical use.
T. Tang, L. Lv, Bin Wang, Jingyuan Cao, Ye Feng, Zuo-Lin Li, Min Wu, Feng-mei Wang, Yi Wen, Le-ting Zhou, H. Ni, Pingsheng Chen, N. Gu, S. Crowley, Bi-Cheng Liu   +14 more
semanticscholar   +1 more source

Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

Journal of Extracellular Vesicles, 2013
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles (EV) has highlighted the potential of these molecules and vehicles as biomarkers of disease and therapeutic targets.
Kenneth W. Witwer, Edit I. Buzás, Lynne T. Bemis, Adriana Bora, Cecilia Lässer, Jan Lötvall, Esther N. Nolte-‘t Hoen, Melissa G. Piper, Sarada Sivaraman, Johan Skog, Clotilde Théry, Marca H. Wauben, Fred Hochberg   +12 more
doaj   +1 more source

Tumoral microvesicle–activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma

The FASEB Journal, 2019
Metabolic reprogramming is a hallmark of cancer. Stromal cells could function as providers of energy metabolites for tumor cells by undergoing the “reverse Warburg effect,” but the mechanism has not been fully elucidated.
E. Jiang, Zhi Xu, Meng Wang, Tinglin Yan, Chun-Ming Huang, Xiaocheng Zhou, Qing Liu, Lin Wang, Yang Chen, Hui Wang, Ke Liu, Z. Shao, Z. Shang   +12 more
semanticscholar   +1 more source

Characterizing Extracellular Vesicles and Their Diverse RNA Contents

Frontiers in Genetics, 2020
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular communication agents that regulate physiological states by transporting
Eren M. Veziroglu, Eren M. Veziroglu, George I. Mias, George I. Mias   +3 more
doaj   +1 more source

Microvesicle-Mediated Delivery of Minicircle DNA Results in Effective Gene-Directed Enzyme Prodrug Cancer Therapy

Molecular Cancer Therapeutics, 2019
An emerging approach for cancer treatment employs the use of extracellular vesicles, specifically exosomes and microvesicles, as delivery vehicles. We previously demonstrated that microvesicles can functionally deliver plasmid DNA to cells and showed ...
M. Kanada, Bryan D Kim, J. Hardy, J. Ronald, Michael H. Bachmann, M. Bernard, G. Perez, A. Zarea, T. Ge, Alicia Withrow, Sherif Abd El-Fattah Ibrahim, Sherif Abd El-Fattah Ibrahim, Victoria Toomajian, S. Gambhir, R. Paulmurugan, C. Contag   +15 more
semanticscholar   +1 more source

Circulating Microvesicles in Regenerative Angiogenesis [PDF]

Current Trends in Biomedical Engineering & Biosciences, 2017
Extracellular microvesicles (EVs) released by different cells have been shown to facilitate the transfer of several pro-angiogenic as well as anti-antigenic factors that can regulate gene expression in endothelial cells. Our recent study has demonstrated that the profiles of cytokines and angiogenic-active factors in EVs are significantly changed in ...
Drożdż, Anna, Stępień, Ewa
openaire   +3 more sources