Results 71 to 80 of about 16,274 (290)
Microvesicles as Mediators of Tissue Regeneration [PDF]
Translational Research, 2014 The use of stem cells in the treatment of various diseases and injuries has received increasing interest during the past decade. Injected stem cells, such as mesenchymal stem cells, stimulate tissue repair largely through the secretion of soluble factors that regulate various processes of tissue regeneration, including inflammatory responses, apoptosis,
Keith, Sabin, Nobuaki, Kikyo
openaire +2 more sources
International Journal of General Medicine, 2023 Procoagulant microvesicles (MVs) are submicron membrane fragments released from activated cells and cells undergoing apoptosis. The procoagulant activity of MVs is enhanced in the presence of tissue factor (TF). MVs and TF are active mediators that induce pro-inflammatory response and prothrombotic tendency and have been linked to the severity of ...
Aymen M Madkhali +9 more
openaire +4 more sources
Frontiers in Immunology, 2018 Inflammatory lung responses are one of the characterized features in the pathogenesis of many lung diseases, including acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD).
Heedoo Lee +4 more
doaj +1 more source
Characterizing Extracellular Vesicles and Their Diverse RNA Contents
Frontiers in Genetics, 2020 Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular communication agents that regulate physiological states by transporting
Eren M. Veziroglu +3 more
doaj +1 more source
Advanced Science, EarlyView.This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
Extracellular vesicles in multiple sclerosis: what are they telling us?
Frontiers in Cellular Neuroscience, 2014 Extracellular vesicles (EVs) are membrane-bound particles secreted by almost all cell types. They are classified depending on their biogenesis and size into exosomes and microvesicles or according to their cell origin.
Matías eSáenz-Cuesta +5 more
doaj +1 more source
Advanced Science, EarlyView.This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir +7 more
wiley +1 more source
Plasma Membrane Lipid Domains as Platforms for Vesicle Biogenesis and Shedding?
Biomolecules, 2018 Extracellular vesicles (EVs) contribute to several pathophysiological processes and appear as emerging targets for disease diagnosis and therapy. However, successful translation from bench to bedside requires deeper understanding of EVs, in particular ...
Hélène Pollet +3 more
doaj +1 more source
, 2014 NAFLD is the most common chronic liver disease, frequently associated with diabetes. Both of these insulin resistant states have increased cardiovascular risk factors associated, and a prevalent cause of mortality in these diseases.
Englyst, Nicola +2 more
core +1 more source
The Fusion Loops of the Initial Prefusion Conformation of Herpes Simplex Virus 1 Fusion Protein Point Toward the Membrane [PDF]
, 2017 All enveloped viruses, including herpesviruses, must fuse their envelope with the host membrane to deliver their genomes into target cells, making this essential step subject to interference by antibodies and drugs.
Atanasiu, D +8 more
core +1 more source