Results 71 to 80 of about 15,195 (308)
Thromboinflammatory effects of RBC microvesicles [PDF]
Blood, 2020 In this issue of Blood, Noubouossie et al provide new insights into potential mechanisms for thromboinflammatory complications associated with red blood cell (RBC) transfusions. By using leukoreduced RBC units to isolate RBC microvesicles (RBC-MVs), they document that RBC-MVs activate factor IX (FIX) via 2 distinct pathways: (1) the canonical ...
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ARRDC1 as a mediator of microvesicle budding [PDF]
Proceedings of the National Academy of Sciences, 2012 Eukaryotic cells critically depend on the formation, budding, and scission of membrane-bounded vesicles for many key processes: internalization of cell surface receptors, delivery of cargo proteins to multivesicular bodies (MVBs) and lysosomes for degradation, transport of newly synthesized proteins between intracellular organelles and their delivery ...
Lillian S. Kuo, Eric O. Freed
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Advancement of science, 2018 A novel metal–organic particle (MOP) based nanodrug formed by mild self‐assembly of chemotherapeutic drugs, including banoxantrone and doxorubicin, through Cu(II)‐mediated coordination effects, is reported.
Da Zhang +10 more
semanticscholar +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, EarlyView.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source
Extracellular Vesicle MicroRNA Transfer in Lung Diseases
Frontiers in Physiology, 2017 MicroRNAs (miRNAs) are single-stranded, small non-coding RNAs that ate involved in the transcriptional and post-transcriptional regulation of gene expression.
Jie Chen, Chengping Hu, Pinhua Pan
doaj +1 more source
Effect of storage on physical and functional properties of extracellular vesicles derived from neutrophilic granulocytes [PDF]
Journal of Extracellular Vesicles, 2014 Aim: To carry out a systematic study on the effect of different storage conditions on the number as well as the physical and functional properties of antibacterial extracellular vesicles (EVs) derived from human neutrophilic granulocytes.
Ákos M. Lőrincz +6 more
doaj +1 more source
Cellular phenotype switching and microvesicles [PDF]
Advanced Drug Delivery Reviews, 2010 Cell phenotype alteration by cell-derived vesicles presents a new aspect for consideration of cell fate. Accumulating data indicates that vesicles from many cells interact with or enter different target cells from other tissues, altering their phenotype toward that of the cell releasing the vesicles.
Jason M. Aliotta, Peter J. Quesenberry
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Adipose-Derived Stem Cells Induce Angiogenesis via Microvesicle Transport of miRNA-31
Stem Cells Translational Medicine, 2016 Cell secretion is an important mechanism for stem cell‐based therapeutic angiogenesis, along with cell differentiation to vascular endothelial cells or smooth muscle cells.
Ting Kang +8 more
semanticscholar +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey +5 more
wiley +1 more source