Results 21 to 30 of about 59,785 (337)

Neutrophil microvesicles and their role in disease [PDF]

open access: yesThe International Journal of Biochemistry & Cell Biology, 2021
Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo derived from their parental cell during formation, including proteases, micro-RNAs and lipids and ...
Reece Dow, Victoria Ridger
openaire   +3 more sources

Microvesicles Transfer Mitochondria and Increase Mitochondrial Function in Brain Endothelial Cells

open access: yesbioRxiv, 2021
We have demonstrated, for the first time that microvesicles, a sub-type of extracellular vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer polarized mitochondria to recipient BECs in culture and to neurons in mice ...
A. D'Souza   +15 more
semanticscholar   +1 more source

R(h)oads to microvesicles [PDF]

open access: bronzeSmall GTPases, 2012
A novel form of cell-to-cell communication involving the formation and shedding of large vesicular structures, called microvesicles (MVs), from the surfaces of highly aggressive forms of human cancer cells has been attracting increasing amounts of attention. This is in large part due to the fact that MVs contain a variety of cargo that is not typically
Marc A. Antonyak   +2 more
openalex   +3 more sources

The Immunomodulatory Role of Syncytiotrophoblast Microvesicles

open access: goldPLoS ONE, 2011
Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards 'type 2' cytokine production ...
Jennifer H. Southcombe   +3 more
openalex   +8 more sources

Microvesicles and Viral Infection [PDF]

open access: yesJournal of Virology, 2011
ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
Nancy Raab-Traub, David G. Meckes
openaire   +3 more sources

Circulating Microvesicles Are Elevated Acutely following Major Burns Injury and Associated with Clinical Severity. [PDF]

open access: yesPLoS ONE, 2016
Microvesicles are cell-derived signaling particles emerging as important mediators and biomarkers of systemic inflammation, but their production in severe burn injury patients has not been described.
Kieran P O'Dea   +6 more
doaj   +1 more source

Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots [PDF]

open access: yes, 2013
This study describes a simple technique that improves a recently developed 3D sub-diffraction imaging method based on three-photon absorption of commercially available quantum dots.
A Franceschetti   +28 more
core   +12 more sources

Microvesicles as immune orchestra conductors

open access: greenBlood, 2008
In this issue of Blood, Sprague and colleagues report that platelet-derived membrane vesicles (PDMVs) orchestrate an immune response sufficient to deliver CD154 signals, which stimulate antigen-specific IgG production and modulate germinal-center formation, by cooperating with responses elucidated by CD4+ T cells.
Mariusz Z. Ratajczak
openalex   +5 more sources

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