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Microvesicles [PDF]

open access: yesCurrent Opinion in Endocrinology, Diabetes & Obesity, 2012
Microvesicles (also known as microparticles) are small membranous structures that are released from platelets and cells upon activation or during apoptosis. Microvesicles have been found in blood, urine, synovial fluid, extracellular spaces of solid organs, atherosclerotic plaques, tumors, and elsewhere.
Ming-Lin, Liu, Kevin Jon, Williams
openaire   +2 more sources

Endothelial cells release microvesicles that harbour multivesicular bodies and secrete exosomes

open access: yesbioRxiv, 2022
Extracellular vesicles (EVs) released by resting endothelial cells support vascular homeostasis. To better understand endothelial cell EV biogenesis, we examined cultured human umbilical vein endothelial cells (HUVECs) prepared by rapid freezing, freeze ...
Jennifer D. Petersen   +4 more
semanticscholar   +1 more source

P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells

open access: yesCell Death and Disease, 2021
Tumor growth and metastatic spreading are heavily affected by the P2X7 receptor as well as microvesicles and exosomes release into the tumor microenvironment. P2X7 receptor stimulation is known to trigger vesicular release from immune and central nervous
A. Pegoraro   +11 more
semanticscholar   +1 more source

Extracellular Vesicles in Hematological Disorders

open access: yesRambam Maimonides Medical Journal, 2014
Extracellular vesicles (EVs), comprised of exosomes, microparticles, apoptotic bodies, and other microvesicles, are shed from a variety of cells upon cell activation or apoptosis.
Anat Aharon   +3 more
doaj   +1 more source

Extracellular vesicles: Exosomes, microvesicles, and friends

open access: yesJournal of Cell Biology, 2013
Cells release into the extracellular environment diverse types of membrane vesicles of endosomal and plasma membrane origin called exosomes and microvesicles, respectively.
G. Raposo, W. Stoorvogel
semanticscholar   +1 more source

Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]

open access: yes, 2003
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike   +9 more
core   +1 more source

R(h)oads to microvesicles [PDF]

open access: yesSmall GTPases, 2012
A novel form of cell-to-cell communication involving the formation and shedding of large vesicular structures, called microvesicles (MVs), from the surfaces of highly aggressive forms of human cancer cells has been attracting increasing amounts of attention. This is in large part due to the fact that MVs contain a variety of cargo that is not typically
Antonyak, Marc A.   +2 more
openaire   +2 more sources

Characterization of physical properties of tissue factor–containing microvesicles and a comparison of ultracentrifuge-based recovery procedures

open access: yesJournal of Extracellular Vesicles, 2014
Microvesicles were isolated from the conditioned media of 3 cell lines (MDA-MB-231, AsPC-1 and A375) by ultracentrifugation at a range of relative centrifugal forces, and the tissue factor (TF) protein and activity, microvesicle number, size distribution
Camille Ettelaie   +3 more
doaj   +1 more source

Microvesicles as vehicles for tissue regeneration: Changing of the guards [PDF]

open access: yes, 2016
Purpose of Review: Microvesicles (MVs) have been recognised as mediators of stem cell function, enabling and guiding their regenerative effects. Recent Findings: MVs constitute one unique size class of extracellular vesicles (EVs) directly shed from ...
Davies, R. Wayne   +3 more
core   +1 more source

MICROVESICLES AND THROMBOSIS IN OBSTETRIC-GYNECOLOGICAL COMPLICATIONS

open access: yesАкушерство, гинекология и репродукция, 2016
Microvesicles (MVs), including microparticles and exosomes, are secreted from a variety of cells. They are present in the blood circulation under normal physiological conditions, and their levels increase in a wide range of disease states.
A. Aharon, B. Brenner
doaj   +1 more source

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