Results 51 to 60 of about 63,152 (354)
Membrane Microvesicles as Potential Vaccine Candidates [PDF]
International Journal of Molecular Sciences, 2021 The prevention and control of infectious diseases is crucial to the maintenance and protection of social and public healthcare. The global impact of SARS-CoV-2 has demonstrated how outbreaks of emerging and re-emerging infections can lead to pandemics of significant public health and socio-economic burden.
Layaly Shkair +5 more
openaire +2 more sources
TH Open, 2019 Tissue factor (TF)-positive microvesicles from various sources can promote cellular proliferation or alternatively induce apoptosis, but the determining factors are unknown.
Yahya Madkhali +5 more
doaj +1 more source
Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells [PDF]
, 2015 Obesity and type 2 diabetes lead to dramatically increased risks of atherosclerosis and CHD. Multiple mechanisms converge to promote atherosclerosis by increasing endothelial oxidative stress and up-regulating expression of pro-inflammatory molecules ...
Bastard +6 more
core +2 more sources
miRNAs as Influencers of Cell-Cell Communication in Tumor Microenvironment [PDF]
, 2020 microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Conti, Ilaria +6 more
core +1 more source
Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Shedding microvesicles are membrane released vesicles derived directly from the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin that share structural and biochemical characteristics with prostasomes ...
Anders Waldenström +3 more
doaj +1 more source
Journal of Extracellular Vesicles, 2016 Extracellular vesicles (EVs), including exosomes and microvesicles (MVs), are explored for use in diagnostics, therapeutics and drug delivery. However, little is known about the relationship of protein and lipid composition of EVs and their source cells.
R. Haraszti +11 more
semanticscholar +1 more source
Experimental Hematology & Oncology, 2019 Background Microvesicles as a new device of cell–cell communication are potentially able to induce some phenotypes and genotypes of an origin cell in a target cell. We evaluate the role of leukemia microvesicles on the leukemia stem cells (LSCs)-specific
Farnaz Razmkhah +3 more
doaj +1 more source
The role of microvesicles as biomarkers in the screening of colorectal neoplasm
Cancer Medicine, 2022 Background Colorectal cancer (CRC) is the second cause of cancer death worldwide. The role of circulating microvesicles as a screening tool is a novel, yet effective approach that warrants prioritised research.
Mohammad M. R. Eddama +6 more
doaj +1 more source
ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth [PDF]
, 2017 Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer death; identifying PDAC enablers may reveal potential therapeutic targets. Expression of the actomyosin regulatory ROCK1 and ROCK2 kinases increased with tumor progression in human and ...
Anderson, Kurt I. +12 more
core +1 more source
PLoS ONE, 2012 Saliva is a useful biofluid for the early detection of disease, but how distal tumors communicate with the oral cavity and create disease-specific salivary biomarkers remains unclear.
Chang S Lau, David T W Wong
doaj +1 more source