Results 81 to 90 of about 136,839 (238)
Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study [PDF]
, 2016 Background: The use of midazolam for dental care in patients with intellectual disability is poorly documented. The purpose of this study was to determine which method of premedication is more effective for these patients, 0.15 mg/kg of intramuscular ...
Boku, Aiji +5 more
core +1 more source
Sedation for Gastrointestinal Endoscopic Procedures in the Elderly: Getting Safer but Still Not Nearly Safe Enough [PDF]
, 2006 Previously published UK reports showed that excessively large doses of benzodiazepines and opiates were being commonly used to sedate elderly patients for gastrointestinal (GI) endoscopy. This unsafe practice has lead to avoidable morbidity and mortality.
Bell, G. D. +8 more
core
Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective [PDF]
, 2019 Over the past two decades, the pig has gained attention as a potential model for human drug metabolism. Cytochrome P450 enzymes (CYP450), a superfamily of biotransformation enzymes, are pivotal in drug metabolism.
Croubels, Siska +7 more
core +1 more source
Pediatric Critical Care Medicine, 2016 Objective: To describe pediatric patients with convulsive refractory status epilepticus in whom there is intention to use an IV anesthetic for seizure control. Design: Two-year prospective observational study evaluating patients (age range, 1 mo to 21 yr)
R. Tasker +19 more
semanticscholar +1 more source
NE contribution to rebooting unconsciousness caused by midazolam
eLifeThe advent of midazolam holds profound implications for modern clinical practice. The hypnotic and sedative effects of midazolam afford it broad clinical applicability.
LeYuan Gu +14 more
doaj +1 more source
Medicine Science, 2018 To compare the effects of ketamine+midazolam or ketamine+propofol on analgesia, sedation and recovery time in children premedicated with midazolam for circumcision operations.
Hatice Toprak +4 more
doaj +1 more source
CHRI sis at the NICU: The Medley with Midazolam [PDF]
, 2021 Approximately 1.5 million neonates undergo anesthesia for surgical procedures in the United States every year1. Midazolam is a commonly used anesthetic agent used in the Neonatal Intensive Care Unit (NICU).
Bhakat, Reeyan +3 more
core +1 more source
Journal of International Medical Research, 2016 Objective A prospective, double-blind, randomized controlled trial to compare the effect of preoperative midazolam or ketamine on the incidence of emergence agitation (EA) following sevoflurane anaesthesia in children.
K. Kim +5 more
semanticscholar +1 more source
Epilepsia, 2015 Benzodiazepines (BZD) are recommended as first‐line treatment for status epilepticus (SE), with lorazepam (LZP) and midazolam (MDZ) being the most widely used drugs and part of current treatment guidelines.
V. Alvarez +6 more
semanticscholar +1 more source
Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans
Frontiers in Genetics, 2020 Human CYP3A enzymes (including CYP3A4 and CYP4A5) metabolize about 40% of all drugs and numerous other environmental and endogenous substances. CYP3A activity is highly variable within and between humans.
Johannes Matthaei +13 more
doaj +1 more source