Results 81 to 90 of about 145,146 (385)

Rapid Design of Efficient Mn3O4‐Based Photocatalysts by Machine Learning and Density Functional Theory Calculations

Advanced Energy and Sustainability Research, EarlyView.
A rapid design strategy is presented for efficient Al‐doped Mn3O4‐based photocatalysts by integrating density functional theory calculations, machine learning (ML) modeling, and experiments. The optimized Al0.5Mn2.5O4/35 wt%‐Ag3PO4 heterojunctions achieved a 27‐fold improvement in methylene blue degradation under visible light compared to pristine ...
Haoxin Mai, Xuying Li, Tu C. Le, Salvy P. Russo, David A. Winkler, Dehong Chen, Rachel A. Caruso   +6 more
wiley   +1 more source

A Comparison of Moderate Oral Sedation Drug Regimens for Pediatric Dental Treatment: A Pilot Study [PDF]

, 2017
Purpose: Compare moderate oral sedation of pediatric patients using Hydroxyzine and Meperidine with either Diazepam or Midazolam in management of pediatric dental patients. Methods: Randomized, double-blind, crossover pilot study of patients 3 to 7 years
Parikh, Ojas A
core   +1 more source

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]

, 2010
Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt, Bebia, Chang, de Morais, Dominique Maiter, Dorota Tomalik-Scharte, Fl  ck, Fuhr, Gomes, Hannah E Ivison, Henderson, Jetter, Julia Kirchheiner, Kelley, Kirchheiner, Kranendonk, Nebert, Nicolo, Parkinson, Porter, Ribes, Sachse, Tantcheva-Po  r, Tomalik-Scharte, Uwe Fuhr, Wiebke Arlt   +25 more
core   +2 more sources

Exploring Potentially Inappropriate Medication Use on Elderly Patients in a General Medicine Ward Using 2023 AGS Beers Criteria

AGING MEDICINE, EarlyView.
This study found that 54% of elderly inpatients were prescribed at least one potentially inappropriate medication (PIM) based on the 2023 AGS Beers Criteria. Among identified PIMs, 32.2% were medications to avoid, and 52.8% required cautious use. Polypharmacy and chronic kidney disease (CKD) were key predictors of PIM use.
Subash Karki, Rahi Bikram Thapa, Rajeev Shrestha   +2 more
wiley   +1 more source

Comparison of the effects of ketamine-midazolam and ketamin-propofol anesthesia on recovery of circumcision operations

Medicine Science, 2018
To compare the effects of ketamine+midazolam or ketamine+propofol on analgesia, sedation and recovery time in children premedicated with midazolam for circumcision operations.
Hatice Toprak, Canan Kocaoglu, Eyup Aydogan, Mehmet Sargin, Sadik Ozmen   +4 more
doaj   +1 more source

Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans

Frontiers in Genetics, 2020
Human CYP3A enzymes (including CYP3A4 and CYP4A5) metabolize about 40% of all drugs and numerous other environmental and endogenous substances. CYP3A activity is highly variable within and between humans.
Johannes Matthaei, Wagner Hugo Bonat, Reinhold Kerb, Mladen Vassilev Tzvetkov, Jakob Strube, Stefanie Brunke, Cordula Sachse-Seeboth, Daniel Sehrt, Ute Hofmann, Jacob von Bornemann Hjelmborg, Matthias Schwab, Matthias Schwab, Matthias Schwab, Jürgen Brockmöller   +13 more
doaj   +1 more source

Vocal learning promotes patterned inhibitory connectivity. [PDF]

, 2017
Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear.
Brainard, Michael S, Cheung, Chung Yan J, Miller, Mark N   +2 more
core   +2 more sources

In Situ Graph Reasoning and Knowledge Expansion Using Graph‐PRefLexOR

Advanced Intelligent Discovery, EarlyView.
Graph‐PRefLexOR is a novel framework that enhances language models with in situ graph reasoning, symbolic abstraction, and recursive refinement. By integrating graph‐based representations into generative tasks, the approach enables interpretable, multistep reasoning.
Markus J. Buehler
wiley   +1 more source

Anti-cancer effect of midazolam via downregulating YWHAH in papillary thyroid cancer cells

Discover Oncology
The work is aimed to investigate whether midazolam functions in thyroid cancer and reveal the potential mechanism of action. Cell viability was detected by CCK-8 method when treated by varying doses of midazolam to detect the cytotoxicity of midazolam on
Yang Li, Ai-Ping Tan, Yu-Shan Zhong
doaj   +1 more source

Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]

, 2012
Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape, B. Zwissler, Barton RG, Cain SM, Eisenberg E, Fontana JL, H. Kertscho, Habler OP, Haller M, Herweling A, Holt JP, Ickx BE, Kampe S, Kemming GI, Kim J, Koskolou MD, Levy PS, M. Lossen, Madjdpour C, Marik PE, McCall M, Meier J, Meier JM, Meier JM, Meier JM, Meisner FG, Messmer KF, Muldoon SM, Naguib M, O. Habler, O. Horn, P. Stein, Pape A, Pape A, Pape A, Perez V, Pittman RN, Richardson RS, Russell WC, S. Kutschker, Schumacker PT, van der Linden P, van der Linden P, van Woerkens EC, Vernon DD, Werlhof V, Zollinger A   +46 more
core   +1 more source