Changes in neural progenitor lineage composition during astrocytic differentiation of human iPSCs [PDF]
eLifeThe regional specificity of stem cell-derived astrocytes is believed to be an important prerequisite for their application in disease modelling and cell-based therapies.
Zongze Li +7 more
doaj +2 more sources
Frontiers in Nutrition, 2023 IntroductionAccumulating evidence suggests that increased neural responses during the anticipation of high-calorie food play an important role in the tendency to overeat. A promising method for counteracting enhanced food anticipation in overeating might
Lieneke K. Janssen +9 more
doaj +1 more source
Responses to dichotic tone-in-noise stimuli in the inferior colliculus
Frontiers in Neuroscience, 2022 Human listeners are more sensitive to tones embedded in diotic noise when the tones are out-of-phase at the two ears (N0Sπ) than when they are in-phase (N0S0).
Langchen Fan +5 more
doaj +1 more source
Application and progress of transcranial substantial ultrasound in Parkinson's disease
Frontiers in Neurology, 2022 Parkinson's disease (PD) is a common nervous system disease, mainly manifested as motor retardation, resting tremor, etc. (1). The clinical features of early PD patients are not characteristic, and diagnosis is very difficult.
Xishun Ma +3 more
doaj +1 more source
Dissociation of task engagement and arousal effects in auditory cortex and midbrain
eLife, 2021 Both generalized arousal and engagement in a specific task influence sensory neural processing. To isolate effects of these state variables in the auditory system, we recorded single-unit activity from primary auditory cortex (A1) and inferior colliculus
Daniela Saderi +4 more
doaj +1 more source
An approach for identifying brainstem dopaminergic pathways using resting state functional MRI. [PDF]
, 2014 Here, we present an approach for identifying brainstem dopaminergic pathways using resting state functional MRI. In a group of healthy individuals, we searched for significant functional connectivity between dopamine-rich midbrain areas (substantia nigra;
D'Esposito, Mark +3 more
core +7 more sources
eLife, 2020 Ascending visual projections similar to the mammalian thalamocortical pathway are found in a wide range of vertebrate species, but their homology is debated. To get better insights into their evolutionary origin, we examined the developmental origin of a
Solal Bloch +12 more
doaj +1 more source
The VTA dopaminergic system as diagnostic and therapeutical target for Alzheimer's disease
Frontiers in Psychiatry, 2022 Neuropsychiatric symptoms (NPS) occur in nearly all patients with Alzheimer's Disease (AD). Most frequently they appear since the mild cognitive impairment (MCI) stage preceding clinical AD, and have a prognostic importance. Unfortunately, these symptoms
Paraskevi Krashia +4 more
doaj +1 more source
Nox2 dependent redox-regulation of microglial response to amyloid-β stimulation and microgliosis in aging [PDF]
, 2020 Microglia express constitutively a Nox2 enzyme that is involved in neuroinflammation by the generation of reactive oxygen species (ROS). Amyloid β (Aβ) plays a crucial role in Alzheimer’s disease.
Fan, Lampson M. +4 more
core +2 more sources
Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users. [PDF]
, 2015 Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors influence amphetamine-induced dopamine release and that dopamine is involved in ...
Dean, AC +5 more
core +4 more sources