Results 21 to 30 of about 212,558 (382)
Application and progress of transcranial substantial ultrasound in Parkinson's disease
Frontiers in Neurology, 2022 Parkinson's disease (PD) is a common nervous system disease, mainly manifested as motor retardation, resting tremor, etc. (1). The clinical features of early PD patients are not characteristic, and diagnosis is very difficult.
Xishun Ma +3 more
doaj +1 more source
Nature Communications, 2021 Three-dimensional brain organoids have emerged as a valuable model system for studies of human brain development and pathology. Here we establish a midbrain organoid culture system to study the developmental trajectory from pluripotent stem cells to ...
A. Fiorenzano +13 more
semanticscholar +1 more source
Neurology, 2009 A 31-year-old man who had been shot with a nail gun was unresponsive at presentation, with unequal, nonreactive pupils. The frontal sinus and right frontal pole were debrided …
Tamara, Lazic, John, Strugar
openaire +2 more sources
An approach for identifying brainstem dopaminergic pathways using resting state functional MRI. [PDF]
, 2014 Here, we present an approach for identifying brainstem dopaminergic pathways using resting state functional MRI. In a group of healthy individuals, we searched for significant functional connectivity between dopamine-rich midbrain areas (substantia nigra;
D'Esposito, Mark +3 more
core +7 more sources
Dissociation of task engagement and arousal effects in auditory cortex and midbrain
eLife, 2021 Both generalized arousal and engagement in a specific task influence sensory neural processing. To isolate effects of these state variables in the auditory system, we recorded single-unit activity from primary auditory cortex (A1) and inferior colliculus
Daniela Saderi +4 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance The origin and mode of action of dopamine on hippocampus-dependent memory have been a matter of interest for many years. The latest research has pointed toward the locus coeruleus as the main source of hippocampal dopamine, while inputs from
T. Tsetsenis +8 more
semanticscholar +1 more source
eLife, 2020 Ascending visual projections similar to the mammalian thalamocortical pathway are found in a wide range of vertebrate species, but their homology is debated. To get better insights into their evolutionary origin, we examined the developmental origin of a
Solal Bloch +12 more
doaj +1 more source
The VTA dopaminergic system as diagnostic and therapeutical target for Alzheimer's disease
Frontiers in Psychiatry, 2022 Neuropsychiatric symptoms (NPS) occur in nearly all patients with Alzheimer's Disease (AD). Most frequently they appear since the mild cognitive impairment (MCI) stage preceding clinical AD, and have a prognostic importance. Unfortunately, these symptoms
Paraskevi Krashia +4 more
doaj +1 more source
Nox2 dependent redox-regulation of microglial response to amyloid-β stimulation and microgliosis in aging [PDF]
, 2020 Microglia express constitutively a Nox2 enzyme that is involved in neuroinflammation by the generation of reactive oxygen species (ROS). Amyloid β (Aβ) plays a crucial role in Alzheimer’s disease.
Fan, Lampson M. +4 more
core +2 more sources
The dopaminergic midbrain participates in human episodic memory formation: Evidence from genetic imaging [PDF]
, 2006 Recent data from animal studies raise the possibility that dopaminergic neuromodulation promotes the encoding of novel stimuli. We investigated a possible role for the dopaminergic midbrain in human episodic memory by measuring how polymorphisms in ...
Bernstein, HG +9 more
core +1 more source