Results 51 to 60 of about 212,558 (382)
Midbrain vasculitic aneurysms [PDF]
Neurology, 2004 This 16-year-old girl had a muscle biopsy demonstrating vasculitis seven years ago when she presented with weakness and Raynaud’s phenomenon (figure, B). Aside from occasional unexplained abdominal pain and chronic anemia, she had been well until one year ago, …
Hyung-Min, Kwon +2 more
openaire +2 more sources
Task-load-dependent activation of dopaminergic midbrain areas in the absence of reward [PDF]
, 2011 Dopamine release in cortical and subcortical structures plays a central role in reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral and cognitive operations ...
Böhler, Nico +6 more
core +2 more sources
Sequential Role of SOXB2 Factors in GABAergic Neuron Specification of the Dorsal Midbrain
Frontiers in Molecular Neuroscience, 2018 Studies proposed a model for embryonic neurogenesis where the expression levels of the SOXB2 and SOXB1 factors regulate the differentiation status of the neural stem cells. However, the precise role of the SOXB2 genes remains controversial.
Neoklis Makrides +5 more
doaj +1 more source
Frontiers in Genetics, 2021 Sonic hedgehog (Shh) signaling regulates multiple morphogenetic processes during embryonic neurogenesis and craniofacial skeletal development. Gpr161 is a known negative regulator of Shh signaling. Nullizygous Gpr161 mice are embryonic lethal, presenting
Sung-Eun Kim +12 more
doaj +1 more source
The Dopaminergic Midbrain Encodes the Expected Certainty about Desired Outcomes [PDF]
, 2014 Dopamine plays a key role in learning; however, its exact function in decision making and choice remains unclear. Recently, we proposed a generic model based on active (Bayesian) inference wherein dopamine encodes the precision of beliefs about optimal ...
Dolan, Ray +4 more
core +2 more sources
Midbrain circuits that set locomotor speed and gait selection
Nature, 2017 Locomotion is a fundamental motor function common to the animal kingdom. It is implemented episodically and adapted to behavioural needs, including exploration, which requires slow locomotion, and escape behaviour, which necessitates faster speeds.
Vittorio Caggiano +14 more
semanticscholar +1 more source
Midbrain Organoids: A New Tool to Investigate Parkinson’s Disease
Frontiers in Cell and Developmental Biology, 2020 The study of human 3D cell culture models not only bridges the gap between traditional 2D in vitro experiments and in vivo animal models, it also addresses processes that cannot be recapitulated by either of these traditional models. Therefore, it offers
Lisa M. Smits, J. Schwamborn
semanticscholar +1 more source
Iodine-123 labeled reboxetine analogues for imaging of noradrenaline transporter in brain using single photon emission computed tomography [PDF]
, 2012 Preliminary investigation of the radioiodinated (S,S)-reboxetine analogue, 123I-INER, in baboons showed this tracer to have promise for imaging the noradrenaline transporter (NAT) using single photon emission computed tomography (SPECT).
Baldwin +26 more
core +1 more source
Midbrain infarct with parkinsonism [PDF]
Neurology, 2003 A 65-year-old dextral woman with hypertension presented with a 5-day history of difficulty writing. On examination, she had impaired adduction of her left eye and micrographia. MRI demonstrated an acute to subacute lacunar infarct involving predominantly the left red nucleus …
John C, Morgan, Kapil D, Sethi
openaire +2 more sources
Cholinergic midbrain afferents modulate striatal circuits and shape encoding of action strategies
Nature Communications, 2020 Assimilation of novel strategies into a consolidated action repertoire is a crucial function for behavioral adaptation and cognitive flexibility. Acetylcholine in the striatum plays a pivotal role in such adaptation, and its release has been causally ...
Daniel Dautan +7 more
semanticscholar +1 more source