Results 91 to 100 of about 6,987 (195)

Proteoglycans and neuronal migration in the cerebral cortex during development and disease [PDF]

, 2015
Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many proteins including growth factors, chemokines, axon guidance molecules,
Nobuaki Maeda
core   +2 more sources

Long-Term Estrogen Receptor Beta Agonist Treatment Modifies the Hippocampal Transcriptome in Middle-Aged Ovariectomized Rats. [PDF]

, 2016
Estradiol (E2) robustly activates transcription of a broad array of genes in the hippocampal formation of middle-aged ovariectomized rats via estrogen receptors (ERalpha, ERbeta, and G protein-coupled ER).
Hrabovszky, E., Kallo, I., Liposits, Zsolt, Rodolosse, A., Sarvari, M., Solymosi, N.   +5 more
core   +1 more source

Midkine in Inflammatory and Toxic Conditions

Current Drug Delivery, 2013
Midkine (MK) is a member of midkine family which is composed of MK and pleotrophin (PTN). MK behaves like a cytokine and growth factor, promotes the proliferation, differentiation, survival, adhesion, migration of cells. MK expression usually increases during ischemia, inflammation, tissue repair, neoplastic transformation and in different toxic ...
openaire   +3 more sources

A guide to selecting high-performing antibodies for human Midkine for use in Western blot and immunoprecipitation [version 3; peer review: 2 approved]

F1000Research
Midkine is a secreted protein that acts as a growth factor or cytokine involved in cell survival and inflammatory processes. It accumulates in amyloid plaques, which are hallmarks of Alzheimer’s Disease (AD). The reproducibility of Midkine research would
Peter S. McPherson, Carl Laflamme, Aled M. Edwards, Kathleen Southern, Riham Ayoubi   +4 more
doaj   +1 more source

Targets for cancer therapy in childhood sarcomas [PDF]

, 2010
Development of chemotherapeutic treatment modalities resulted in a dramatic increase in the survival of children with many types of cancer. Still, in case of some pediatric cancer entities including rhabdomyosarcoma, osteosarcoma and Ewing's sarcoma ...
Amstutz, Armistead, Ashkenazi, Baer, Bagatell, Balasubramanian, Barlow, Baselga, Beat W. Schäfer, Bellamy, Benesch, Bennicelli, Benson, Beppu, Bernasconi, Bersani, Bettayeb, Boerner, Bolden, Bond, Bozzi, Caldas, Cao, Cen, Ciccarelli, Clayer, Coltella, Contardi, Crabbe, Croci, Cullinan, Dagher, Dalal, Dass, Dass, Dauphinot, Davicioni, Dazzi, Do, Dudley, Evdokiou, Ferracini, Ferrara, Folkman, Fouladi, Ganjavi, Ganjavi, Gee, Glade Bender, Gonzalez, Gordon, Greenberg, Guan, Guan, Guba, Helman, Hosoi, Hotta, Houghton, Houghton, Houghton, Huang, Hurtubise, Imai, Iolascon, Izeradjene, Jaboin, Jain, Jankowski, Jemal, Jin, Johnson, Kalebic, Kalebic, Karagiannis, Kaya, Kaya, Kelly, Kolb, Komdeur, Kontny, Kovar, Kubo, Kumar, Kurmasheva, Kutko, Lauricella, Lesko, Li, Li, Linabery, Lissat, Lock, Locklin, Lu, MacEwen, Mackall, Maehara, Maelandsmo, Maki, Maloney, Malumbres, Manara, Marampon, Marco Wachtel, Maris, Maris, Martins, Martins, Masood, Mateo-Lozano, McDowell, McGary, McGary, Mercer, Merchant, Migliore, Miller, Mirandola, Mitsiades, Montagut, Morris, Mu, Naka, Nakatani, Nardone, Neale, Obana, Ohali, Okada, Onisto, Park, Patane, Petak, Petricoin, Rees, Roeb, Roh, Rosenberg, Saab, Sachdev, Sakimura, Sanceau, Sarfaraz, Sato, Scotlandi, Scotlandi, Scotlandi, Scotlandi, Scotlandi, Scotlandi, Scotlandi, Scotlandi, Shapiro, Sharp, Shetty, Shor, Smith, Smith, Smithey, Sonnemann, Spreafico, Sulzbacher, Sulzbacher, Taniguchi, Taulli, Thimmaiah, Tirado, Tomek, Trotman, van den Broeke, van der Geer, Van Valen, Vivanco, Voskoglou-Nomikos, Wachtel, Walczak, Wan, Wan, Wang, Wang, Warzecha, Watanabe, Weinstein, Whitlock, Workman, Wu, Yan, Yap, Ye, Yin, Yuan, Zhang, Zhang, Zhang, Zhang   +195 more
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Monocyte‐Derived Macrophages‐Synovial Fibroblasts Crosstalk Unravels Oncostatin Signaling Network as a Driver of Synovitis in Osteoarthritis

Arthritis &Rheumatology, Volume 78, Issue 1, Page 105-118, January 2026.
Objective Osteoarthritis (OA) is a debilitating joint disease that is characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origins and functions of diverse macrophage subsets seeding the synovial joint tissue remain incompletely understood.
Damien Laouteouet, Olivier Bortolotti, Léa Marineche, Nicole Hannemann, Manon Chambon, Yaël Glasson, Anne‐Sophie Dumé, Julien De Lima, Maud Fournial, Dylan Touchet, Dany Séverac, Felicia Leccia, Christophe Duperray, Henri‐Alexandre Michaud, Farida Djouad, Benoît Le Goff, Frédéric Blanchard, Florence Apparailly, Gabriel Courties   +18 more
wiley   +1 more source

Use of retinoids during oocyte maturation diminishes apoptosis in caprine embryos [PDF]

, 2015
Exposure of caprine oocytes and embryos to retinoids enhances embryonic development, but the mechanisms governing this phenomenon have not been characterised.
Cantanhêde, Ludymila F., Chaves, Ricardo M., Conceição, Juliana C. Z., Ferreira-Silva, José C., Lima, Paulo F., Moura, Marcelo T., Oliveira, Marcos A. L., Ramos-Deus, Pamela, Silva, Priscila G. C.   +8 more
core   +1 more source

Role of Macrophages in Cardiac Remodeling: Cues From Zebrafish Heart

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
The figure illustrates the role of macrophage polarization in cardiac damage and repair, highlighting monocyte to M0, M1, and M2 macrophage differentiation. M1 macrophages, in response to pro‐inflammatory cytokines (e.g., IFNγ, TNF‐α, IL‐6), are involved in fibrosis and scarring in the heart.
Himanshu Gaur, Maram Hasan, Huseyin C. Yalcin   +2 more
wiley   +1 more source

Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration

eLife, 2020
Formation of a specialized wound epidermis is required to initiate salamander limb regeneration. Yet little is known about the roles of the early wound epidermis during the initiation of regeneration and the mechanisms governing its development into the ...
Stephanie L Tsai, Clara Baselga-Garriga, Douglas A Melton   +2 more
doaj   +1 more source

Oocytes recovered from cows treated with retinol become unviable as blastocysts produced in vitro [PDF]

, 2011
Retinoids have been shown to enhance developmental competence of the oocyte in cattle, sheep and pigs. In this study we investigated whether exogenous retinol stimulates the bovine oocyte during its intrafollicular growth and the time limits of exposure ...
Alonso, Cristina, Duque, Paloma, Díez, Carmen, Facal, Nieves, Fernández, Itziar, Goyache, Félix, Gómez, Enrique, Hidalgo, C.O. (Carlos), Ikeda, S., Prendes, J.M. (J.), Rodríguez, Aida   +10 more
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