Results 41 to 50 of about 7,018 (211)
Frontiers in Endocrinology, 2022 IntroductionCurrently there are no biomarkers that are predictive of when patients with type-2 diabetes (T2D) will progress to more serious kidney disease i.e., diabetic nephropathy (DN).
Carla Harkin +11 more
doaj +1 more source
Mesenchymal stem cells with overexpression of midkine enhance cell survival and attenuate cardiac dysfunction in a rat model of myocardial infarction [PDF]
, 2014 Introduction. Elevated midkine (MK) expression may contribute to ventricular remodeling and ameliorate cardiac dysfunction after myocardial infarction (MI).
Chen, S.-L. (Shao-Liang) +4 more
core +10 more sources
Embryological Origin of Human Smooth Muscle Cells Influences Their Ability to Support Endothelial Network Formation. [PDF]
, 2016 UNLABELLED: Vascular smooth muscle cells (SMCs) from distinct anatomic locations derive from different embryonic origins. Here we investigated the respective potential of different embryonic origin-specific SMCs derived from human embryonic stem cells ...
Bargehr, Johannes +7 more
core +2 more sources
Sakarya Tıp Dergisi, 2017 Objective: Hypertension (HT) is one of the risk factors associated with dementia. Our aim was to research cognitive functions in patients with HT and its relationship to midkine levels in serum.
Eda Celik Guzel +8 more
doaj +1 more source
Frontiers in Physiology, 2017 Mycophenolic acid (MPA) is prescribed to prevent allograft rejection in organ transplanted patients. However, its use is sporadically linked to leak flux diarrhea and other gastrointestinal (GI) disturbances in around 75% of patients through yet unknown ...
Niamat Khan +7 more
doaj +1 more source
Midkine Deficiency Attenuates Lipopolysaccharide-Induced Pulmonary Inflammation. [PDF]
Int J Mol SciMidkine (MDK) is a multifunctional heparin-binding growth factor, and has been shown to regulate cell growth, survival and migration. It also plays important roles in several inflammatory diseases such as sepsis. However, the role of MDK in the lungs has not yet been elucidated.
Tanino Y +8 more
europepmc +3 more sources
Pleiotrophin as a central nervous system neuromodulator, evidences from the hippocampus [PDF]
, 2015 Pleiotrophin (PTN) is a secreted growth factor, and also a cytokine, associated with the extracellular matrix, which has recently starting to attract attention as a significant neuromodulator with multiple neuronal functions during development.
González Castillo, Celia +4 more
core +2 more sources
Marine Drugs, 2022 Different classes of phytochemicals were previously isolated from the Red Sea algae Hypnea musciformis as sterols, ketosteroids, fatty acids, and terpenoids. Herein, we report the isolation of three fatty acids—docosanoic acid 4, hexadecenoic acid 5, and
Sameh S. Elhady +13 more
doaj +1 more source
Midkine mediates intercellular crosstalk between drug-resistant and drug sensitive neuroblastoma cells in vitro and in vivo [PDF]
, 2013 Resistance to cytotoxic agents has long been known to be a major limitation in the treatment of human cancers. Although many mechanisms of drug resistance have been identified, chemotherapies targeting known mechanisms have failed to lead to effective ...
Chou, Pauline M +9 more
core +3 more sources
Neuroinflammation and Its Resolution: From Molecular Mechanisms to Therapeutic Perspectives [PDF]
, 2020 Neuroinflammation, the complex immune response of the central nervous system (CNS), when sustained, is a common denominator in the etiology and course of all major neurological diseases, including neurodevelopmental, neurodegenerative, and psychiatric ...
Berwian +11 more
core +2 more sources